Standout Papers

CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca <sup>2+... 2001 2026 2009 2017 1.1k
  1. CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca 2+ Entry (2006)
    Monika Vig, Christine Peinelt et al. Science
  2. LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability (2001)
    Monica J. S. Nadler, Meredith C. Hermosura et al. Nature

Citation Impact

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Outer Pore Architecture of a Ca2+-selective TRP Channel
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The Recombinant Human TRPV6 Channel Functions as Ca2+Sensor in Human Embryonic Kidney and Rat Basophilic Leukemia Cells
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Irritant-evoked activation and calcium modulation of the TRPA1 receptor
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QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells
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The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
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Piezo proteins are pore-forming subunits of mechanically activated channels
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Structure–functional intimacies of transient receptor potential channels
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2-Aminoethoxydiphenyl Borate Activates and Sensitizes the Heat-Gated Ion Channel TRPV3
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Voltage‐dependent conductance changes in the store‐operated Ca2+ current ICRAC in rat basophilic leukaemia cells
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Ca2+ Modulation of Ca2+ Release-Activated Ca2+ Channels Is Responsible for the Inactivation of Its Monovalent Cation Current
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Fast Calcium-Dependent Inactivation of Calcium Release-Activated Calcium Current (CRAC) in RBL-1 Cells
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Biochemical and Functional Characterization of Orai Proteins
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PIP2 and PIP3 interact with N-terminus region of TRPM4 channel
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Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
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Store-Operated Calcium Channels
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Ca2+-dependent capacitance increases in rat basophilic leukemia cells following activation of store-operated Ca2+ entry and dialysis with high-Ca2+-containing intracellular solution
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Homo- and heteromeric assembly of TRP channel subunits
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Orai1 is an essential pore subunit of the CRAC channel
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Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
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Respiring mitochondria determine the pattern of activation and inactivation of the store-operated Ca2+ current ICRAC
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Regulation of the Ca2+ Sensitivity of the Nonselective Cation Channel TRPM4
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Interaction of STIM1 with Endogenously Expressed Human Canonical TRP1 upon Depletion of Intracellular Ca2+ Stores
2006
TRPV3 is a calcium-permeable temperature-sensitive cation channel
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Slow Feedback Inhibition of Calcium Release-activated Calcium Current by Calcium Entry
1998
Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain
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2000
Delayed Activation of the Store-operated Calcium Current Induced by Calreticulin Overexpression in RBL-1 Cells
1998
TRP Channel Proteins and Signal Transduction
2002
Structure of the mammalian TRPM7, a magnesium channel required during embryonic development
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Structure and Regulation of Voltage-Gated Ca2+ Channels
2000 Standout
Diethylstilbestrol is a potent inhibitor of store-operated channels and capacitative Ca(2+) influx.
2004
Diethylstilbestrol Is a Potent Inhibitor of Store-Operated Channels and Capacitative Ca2+ Influx
2004
PERMEATION AND SELECTIVITY OF TRP CHANNELS
2005
Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry
2003
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients
2005
Physiological Features of Visceral Smooth Muscle Cells, With Special Reference to Receptors and Ion Channels
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TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells
2009
Ion Channels and Their Functional Role in Vascular Endothelium
2001
The TRP Superfamily of Cation Channels
2005
Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels
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Receptor-activated Ca2+ inflow in animal cells: a variety of pathways tailored to meet different intracellular Ca2+ signalling requirements
1999
Regulation of CRAC Channel Activity by Recruitment of Silent Channels to a High Open-probability Gating Mode
2006
Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals
2007 StandoutNobel
Mg2+-dependent Gating and Strong Inward Rectification of the Cation Channel TRPV6
2003
Regulation of Ca2+ release-activated Ca2+channels by INAD and Ca2+ influx factor
2003
Capacitative Ca2+ Entry Is Closely Linked to the Filling State of Internal Ca2+ Stores: A Study Using Simultaneous Measurements of ICRAC and Intraluminal [Ca2+]
1998
Immobilizing the Moving Parts of Voltage-Gated Ion Channels
2000
The identification of a volume‐regulated anion channel: an amazingOdyssey
2015
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids
1999
Distinct Properties of CRAC and MIC Channels in RBL Cells
2002
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions
2006
A store-operated nonselective cation channel in lymphocytes is activated directly by Ca2+ influx factor and diacylglycerol
2001
TRPA1: A Gatekeeper for Inflammation
2012
Phototransduction in Drosophila melanogaster
2001
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
2019 Science
Stimulation of GLP-1 Secretion Downstream of the Ligand-Gated Ion Channel TRPA1
2014
PLC-γ: an old player has a new role
2002
Capacitative calcium entry in the nervous system
2003
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Calcium Signaling Mechanisms in T Lymphocytes
2001
Critical Role for Transient Receptor Potential Channel TRPM4 in Myogenic Constriction of Cerebral Arteries
2004
TRP Channels
2007 Standout
Genome-wide RNAi screen of Ca 2+ influx identifies genes that regulate Ca 2+ release-activated Ca 2+ channel activity
2006
Capacitative Calcium Entry Deficits and Elevated Luminal Calcium Content in Mutant Presenilin-1 Knockin Mice
2000
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Toward a Consensus on the Operation of Receptor-Induced Calcium Entry Signals
2004
Evidence that Ca2+-release-activated Ca2+ channels in rat hepatocytes are required for the maintenance of hormone-induced Ca2+ oscillations
2003
Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel
2002
The molecular choreography of a store-operated calcium channel
2007 Nature
Ca2+ Regulation of TRP Ion Channels
2018
Physiology of Microglia
2011 Standout
Evidence for the involvement of a small subregion of the endoplasmic reticulum in the inositol trisphosphate receptor-induced activation of Ca2+ inflow in rat hepatocytes
1999
Single Channel Properties and Regulated Expression of Ca2+ Release-Activated Ca2+ (Crac) Channels in Human T Cells
2000

Works of Andrea Fleig being referenced

TRPM7 Provides an Ion Channel Mechanism for Cellular Entry of Trace Metal Ions
2002
CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca 2+ Entry
2006 StandoutScience
TRPM5 is a transient Ca 2+ -activated cation channel responding to rapid changes in [Ca 2+ ] i
2003
TRPM4 Regulates Calcium Oscillations After T Cell Activation
2004 Science
TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice
2013
TRPM4 controls insulin secretion in pancreatic β-cells
2006
TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization
2002
InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase
2000 Nature
TRPM7 is essential for Mg2+ homeostasis in mammals
2010
LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability
2001 StandoutNature
The TRPM ion channel subfamily: molecular, biophysical and functional features
2004
Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor.
1996
TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
2008
Cyclic ADP-Ribose and Hydrogen Peroxide Synergize with ADP-Ribose in the Activation of TRPM2 Channels
2005
CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel
2006
Regulation of Vertebrate Cellular Mg2+ Homeostasis by TRPM7
2003
Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches
1994
Silent calcium channels generate excessive tail currents and facilitation of calcium currents in rat skeletal myoballs.
1996
Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils
2008
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
2001 Nature
Calcium Release-activated Calcium Current (I CRAC) Is a Direct Target for Sphingosine
1998
The Store-Operated Calcium Current ICRAC: Nonlinear Activation by InsP3 and Dissociation from Calcium Release
1997
Lipopolysaccharide‐induced down‐regulation of Ca2+release‐activated Ca2+currents (ICRAC) but not Ca2+‐activated TRPM4‐like currents (ICAN) in cultured mouse microglial cells
2007
The TRPM6 Kinase Domain Determines the Mg·ATP Sensitivity of TRPM7/M6 Heteromeric Ion Channels
2014
The calcium‐permeable non‐selective cation channel TRPM2 is modulated by cellular acidification
2010
CRACM1, CRACM2, and CRACM3 Are Store-Operated Ca2+ Channels with Distinct Functional Properties
2007
CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties
2001
Dissociation of the store‐operated calcium current ICRAC and the Mg‐nucleotide‐regulated metal ion current MagNuM
2002
TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD
2006
Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity
2003
Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain
2004
Regulation of TRPM2 by Extra- and Intracellular Calcium
2007
TRPM2 Functions as a Lysosomal Ca2+-Release Channel in β Cells
2009
Store-Operated Calcium Entry: A Tough Nut to CRAC
2004
Dendritic cell maturation and chemotaxis is regulated by TRPM2‐mediated lysosomal Ca 2+ release
2011
Transient Receptor Potential 1 Regulates Capacitative Ca2+ Entry and Ca2+ Release from Endoplasmic Reticulum in B Lymphocytes
2002
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
2006
Emerging Roles of TRPM Channels
2004
Nicotinic acid adenine dinucleotide phosphate and cyclic ADP‐ribose regulate TRPM2 channels in T lymphocytes
2006
TRPM7 Channel Is Regulated by Magnesium Nucleotides via its Kinase Domain
2006
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