Andrea Ecker

Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells

The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma

The re-emergence of natural products for drug discovery in the genomics era

The Molecular Signatures Database Hallmark Gene Set Collection

Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine

Hypoxia and the extracellular matrix: drivers of tumour metastasis

Target identification and mechanism of action in chemical biology and drug discovery

Identification and validation of genes involved in cervical tumourigenesis

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

Resisting viral infection: the gene by gene approach

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence

An Overexpression Screen of Toxoplasma gondii Rab-GTPases Reveals Distinct Transport Routes to the Micronemes

Targeting autophagy in cancer

Discovery and resupply of pharmacologically active plant-derived natural products: A review

Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib

The role of Stat5 transcription factors as tumor suppressors or oncogenes

Molecular Docking and Structure-Based Drug Design Strategies

STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain

Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective

Loss of STAT3 in murine NK cells enhances NK cell–dependent tumor surveillance

Antimalarial drug discovery: targeting protein kinases

Plasmodium berghei: Plasmodium perforin-like protein 5 is required for mosquito midgut invasion in Anopheles stephensi

Reverse genetics screen identifies six proteins important for malaria development in the mosquito

Plasmodium berghei calcium‐dependent protein kinase 3 is required for ookinete gliding motility and mosquito midgut invasion

The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor

Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence

How Can we Identify Parasite Genes that Underlie Antimalarial Drug Resistance?