Citation Impact
Citing Papers
Structural insights into peptide bond formation
2002 StandoutNobel
The ribosome as an entropy trap
2004
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome
2008 StandoutScienceNobel
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
The RNA Helicases AtMTR4 and HEN2 Target Specific Subsets of Nuclear Transcripts for Degradation by the Nuclear Exosome in Arabidopsis thaliana
2014
tRNA selection and kinetic proofreading in translation
2004 Nobel
The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome
2001
The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity
2005
A conformational switch controls hepatitis delta virus ribozyme catalysis
2004 StandoutNatureNobel
Mapping Functionally Important Motifs SPF and GGQ of the Decoding Release Factor RF2 to the Escherichia coli Ribosome by Hydroxyl Radical Footprinting
2003
In vivo determination of RNA Structure-Function relationships: analysis of the 790 loop in ribosomal RNA 1 1Edited by D. E. Draper
1997
Disordered RNA chaperone proteins: from functions to disease
2005
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits
2002 StandoutNobel
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
2000 StandoutNatureNobel
A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
1998 StandoutNobel
Ribozyme-catalysed amino-acid transfer reactions
1996 StandoutNatureNobel
Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451
2005
Essential Mechanisms in the Catalysis of Peptide Bond Formation on the Ribosome
2005
The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA
1992 StandoutNatureNobel
Structure of the 30S ribosomal subunit
2000 StandoutNatureNobel
High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
2001 StandoutNobel
The Path to Perdition Is Paved with Protons
2002
Important Contribution to Catalysis of Peptide Bond Formation by a Single Ionizing Group within the Ribosome
2002
The Active Site of the Ribosome Is Composed of Two Layers of Conserved Nucleotides with Distinct Roles in Peptide Bond Formation and Peptide Release
2004
A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome
1995 Nature
Mutations at nucleotides G2251 and U2585 of 23 S rRNA perturb the peptidyl transferase center of the ribosome
1997
Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts
1997
Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns
1990 StandoutNatureNobel
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
[3H]-p-Azidopuromycin photoaffinity labeling of Escherichia coli ribosomes: evidence for site-specific interaction at U-2504 and G-2502 in domain V of 23S ribosomal RNA
1988
Peptide bond formation on the ribosome: structure and mechanism
2003
Structure of a bacterial 30S ribosomal subunit at 5.5 Å resolution
1999 StandoutNatureNobel
After the ribosome structures: How does peptidyl transferase work?
2003 StandoutNobel
Movement of the 3′‐end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics
1997
A cryo-electron microscopic study of ribosome-bound termination factor RF2
2003 StandoutNatureNobel
Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide
2001 Nature
Peptide bond formation does not involve acid-base catalysis by ribosomal residues
2006
Mononucleotide derivatives as ribosomal P-site substrates reveal an important contribution of the 2'-OH to activity
2003
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit
1999 StandoutNatureNobel
The Critical Role of the Universally Conserved A2602 of 23S Ribosomal RNA in the Release of the Nascent Peptide during Translation Termination
2003
On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes
2003 StandoutNobel
Multiple alignment using simulated annealing: branch point definition in human mRNA splicing
1992
Structural Insights into the Roles of Water and the 2′ Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction
2005 StandoutNobel
From peptide‐bond formation to cotranslational folding: dynamic, regulatory and evolutionary aspects
2004 StandoutNobel
Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine
1995 StandoutNatureNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Ribosomal crystallography: Peptide bond formation and its inhibition
2003 StandoutNobel
Transit of tRNA through the Escherichia coli ribosome: cross‐linking of the 3′ end of tRNA to ribosomal proteins at the P and E sites
2002
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Base-Pairing between 23S rRNA and tRNA in the Ribosomal A Site
1999
Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features
1998 Nobel
Mutually exclusive splicing of α-tropomyosin exons enforced by an unusual lariat branch point location: Implications for constitutive splicing
1989
Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide‐bond formation, chirality discrimination and antibiotics synergism
2004 StandoutNobel
An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination
2007
High-resolution Structures of Ribosomal Subunits: Initiation, Inhibition, and Conformational Variability
2001 StandoutNobel
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
The Elongation Phase of Protein Synthesis
1996
How are tRNAs and mRNA arranged in the ribosome? An attempt to correlate the stereochemistry of the tRNA-mRNA interaction with constraints imposed by the ribosomal topography
1992
A Protein Component at the Heart of an RNA Machine: The Importance of Protein L27 for the Function of the Bacterial Ribosome
2005
Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites
1989
Symmetry at the active site of the ribosome: structural and functional implications
2005 StandoutNobel
Solid phase synthesis and binding affinity of peptidyl transferase transition state mimics containing 2'-OH at P-site position A76
2004
Ribosomal Tolerance and Peptide Bond Formation
2003 StandoutNobel
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Ribosomal antibiotics: structural basis for resistance, synergism and selectivity
2004 StandoutNobel
The Role of 23S Ribosomal RNA Residue A2451 in Peptide Bond Synthesis Revealed by Atomic Mutagenesis
2008
Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression
2003 StandoutNobel
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
2005 StandoutNatureNobel
Preparation and activity of synthetic unmodified mammalian tRNAi Met in initiation of translation in vitro
2001
The role of the mammalian branchpoint sequence in pre-mRNA splicing.
1988
The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 Å resolution
2000
Progress Toward an Understanding of the Structure and Enzymatic Mechanism of the Large Ribosomal Subunit
2001 StandoutNobel
Ribosome Structure and the Mechanism of Translation
2002 StandoutNobel
Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns
1989 Nature
Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template
2004 StandoutNatureNobel
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Evidence against stabilization of the transition state oxyanion by a pKa-perturbed RNA base in the peptidyl transferase center
2002
Crystal Structure of the Ribosome at 5.5 Å Resolution
2001 StandoutScience
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
The Structure of Ribosomal RNA: A Three‐Dimensional Jigsaw Puzzle
1995
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
2006 StandoutNobel
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel
Mapping the rRNA neighborhood of the acceptor end of tRNA in the ribosome.
1996
Review
1998
Characterization of functionally active subribosomal particles from Thermus aquaticus
1999
Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes
1982 Nature
Higher order structural elements in ribosomal RNAs: pseudo-knots and the use of noncanonical pairs.
1990
Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes
1986
The Structural Basis of Large Ribosomal Subunit Function
2003 StandoutNobel
The Role of Disordered Ribosomal Protein Extensions in the Early Steps of Eubacterial 50 S Ribosomal Subunit Assembly
2009
The Search and Its Outcome: High-Resolution Structures of Ribosomal Particles from Mesophilic, Thermophilic, and Halophilic Bacteria at Various Functional States
2002 StandoutNobel
A Single Adenosine with a Neutral p K a in the Ribosomal Peptidyl Transferase Center
2000 Science
Sequence at the Site of Attachment of an Affinity‐Label Derivative of Puromycin on 23‐S Ribosomal RNA of Escherichia coli Ribosomes
1978
pH-dependent conformational flexibility within the ribosomal peptidyl transferase center.
2001
Kinetic Isotope Effect Analysis of the Ribosomal Peptidyl Transferase Reaction
2005
Labeling the peptidyltransferase center of the Escherichia coli ribosome with photoreactive tRNA(Phe) derivatives containing azidoadenosine at the 3' end of the acceptor arm: a model of the tRNA-ribosome complex.
1989
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Direct Visualization of A-, P-, and E-Site Transfer RNAs in the Escherichia coli Ribosome
1996 StandoutScienceNobel
RNA-Protein Interactions in 30 S Ribosomal Subunits: Folding and Function of 16 S rRNA
1989 Science
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Catalytic Strategies of the Hepatitis Delta Virus Ribozymes
2002
Ribosome-Catalyzed Peptide-Bond Formation with an A-Site Substrate Covalently Linked to 23 S Ribosomal RNA
1998 Science
RIBOSOMES AND TRANSLATION
1997
Ribosomal components from Escherichia coli 50 S subunits involved in the reconstitution of peptidyltransferase activity.
1981
Distance moved by transfer RNA during translocation from the A site to the P site on the ribosome
1982
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit
2001
Specific Interactions in RNA Enzyme-Substrate Complexes
1989 StandoutScienceNobel
Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes
1982
The potential for manipulating RNA with pentatricopeptide repeat proteins
2013
Functional aspects of ribosomal architecture: symmetry, chirality and regulation
2004 StandoutNobel
Binding of Aminoacyl‐tRNA to Reconstituted Subparticles of Escherichia coli Large Ribosomal Subunits
1976
Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptide
2006
Introns increase transcriptional efficiency in transgenic mice.
1988
Unusual Resistance of Peptidyl Transferase to Protein Extraction Procedures
1992 Science
Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA.
1991
Erythromycin resistance by ribosome modification
1995
UACUAAC is the preferred branch site for mammalian mRNA splicing.
1989
Three recognition events at the branch-site adenine.
1996
The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA.
1988
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
The process of mRNA–tRNA translocation
2007 StandoutNobel
Topological arrangement of two transfer RNAs on the ribosome
1983
Identification of Binding Sites on the E. Coli Ribosome by Affinity Labeling
1977
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
1984 StandoutNatureNobel
Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination
1985 StandoutNatureNobel
The decoding region of 16S RNA; a cross-linking study of the ribosomal A, P and E sites using tRNA derivatized at position 32 in the anticodon loop.
1994
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
1990 StandoutScienceNobel
Works of Andrea Barta being referenced
Lead-catalysed specific cleavage of ribosomal RNAs
1997
Strategies for RNA folding and assembly
2004
Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex.
1992
Alternative splicing in plants – coming of age
2012
Metal ion probing of rRNAs: Evidence for evolutionarily conserved divalent cation binding pockets
1998
Interactions of Arabidopsis RS Domain Containing Cyclophilins with SR Proteins and U1 and U11 Small Nuclear Ribonucleoprotein-specific Proteins Suggest Their Involvement in Pre-mRNA Splicing
2004
Molecular aspects of the ribosomal peptidyl transferase
2002
Primary structure and evolution of rat growth hormone gene.
1981
Unusual branch point selection in processing of human growth hormone pre-mRNA.
1988
Photo‐Induced Crosslinking between Phenylalanine Transfer RNA and Messenger RNA on the Escherichia coli Ribosome
1980
Photoaffinity labelling of 23 S RNA at the donor‐site of the Escherichia coli ribosome
1975
Mechanism of Ribosomal Peptide Bond Formation
2001 Science
Mechanism of translocation: relative arrangement of tRNA and mRNA on the ribosome.
1980
A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition
2001
Unusual Branch Point Selection in Processing of Human Growth Hormone Pre-mRNA
1988
Identification of a site on 23S ribosomal RNA located at the peptidyl transferase center.
1984
Photo-affinity labelling at the peptidyl transferase centre reveals two different positions for the A- and P-sites in domain V of 23S rRNA.
1988
Periodic Conformational Changes in rRNA
2000