Standout Papers
Citation Impact
Citing Papers
The lattice as allosteric effector: Structural studies of αβ- and γ-tubulin clarify the role of GTP in microtubule assembly
2008
Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor–dependent signaling pathways in renal collecting duct cells
2010
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus
2006 StandoutNobel
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
2013 Science
A TOG:αβ-tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
2012 Science
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
Identification of the homologous beige and Chediak–Higashi syndrome genes
1996 Nature
Phosphodiesterase 4D and Protein Kinase A Type II Constitute a Signaling Unit in the Centrosomal Area
2001
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers
2010
The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis
1992
Neuronal phosphoproteins
1987
Functional architecture of the nicotinic acetylcholine receptor: A prototype of ligand-gated ion channels
1993
Changing the Structural Context of a Functional β-Hairpin
1996
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
Regulatory T Cells
2000 StandoutNobel
The TiPS lecture the nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels
1990
Regional regulation of microtubule dynamics in polarized, motile cells
1999
Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen‐activated protein (MAP) kinase and MAP‐kinase‐activated kinases 1 and 2
1993
New Insights into the Mechanisms of Cytomotive Actin and Tubulin Filaments
2011
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Structural Basis of Interprotofilament Interaction and Lateral Deformation of Microtubules
2010
Historical review: A brief history and personal retrospective of seven-transmembrane receptors
2004 StandoutNobel
Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives
2006
The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin
2011
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Three-dimensional structure of Escherichia coli RNA polymerase holoenzyme determined by electron crystallography
1989 StandoutNatureNobel
Regulation of neurotransmitter receptor desensitization by protein phosphorylation
1990
Nucleotide-Dependent Lateral and Longitudinal Interactions in Microtubules
2013
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
1991 StandoutNatureNobel
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly
2005 Nature
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization
1988 StandoutNatureNobel
Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
1990 StandoutNatureNobel
Membrane traffic in polarized neurons
1998
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
2002 StandoutNatureNobel
Accessory protein regulation of microtubule dynamics throughout the cell cycle
1999
The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
1988 StandoutNobel
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
Three-dimensional structure of yeast RNA polymerase II at 16 Å resolution
1991 StandoutNobel
Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex
1999 StandoutNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends
2012
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Separation of Signal Transduction and Adaptation Functions of the Aspartate Receptor in Bacterial Sensing
1983 Science
Rotational mobility of the membrane‐bound acetylcholine receptor of torpedo electric organ measured by phosphorescence depolarisation
1980
Studies of the composition of purified Torpedo californica acetylcholine receptor and of its subunits
1979
Phosphorylation of the receptor for immunoglobulin E
1982
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Subunit structure and peptide mapping of junctional and extrajunctional acetylcholine receptors from rat muscle
1979
Calmodulin-stimulated phosphorylation of 17 beta-estradiol receptor on tyrosine.
1984
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes
1981 StandoutNatureNobel
Direct structural localization of two toxin-recognition sites on an ACh receptor protein
1982 StandoutNatureNobel
Structure and function of an acetylcholine receptor
1982
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Analysis of Autoimmunity through Experimental Models of Thyroiditis and Allergic Encephalomyelitis
1980
Structural changes in alkaline-treated postsynaptic membranes from Torpedo marmorata are not due to lipid hydrolysis
1982
Experimental Approaches to Understanding the Role of Protein Phosphorylation in the Regulation of Neuronal Function
1983
A postsynaptic Mr 58,000 (58K) protein concentrated at acetylcholine receptor-rich sites in Torpedo electroplaques and skeletal muscle.
1987
Azotobacter vinelandii ferredoxin I. Aspartate 15 facilitates proton transfer to the reduced [3Fe-4S] cluster.
1993
Presence of a protein immunologically related to lamin B in the postsynaptic membrane of Torpedo marmorata electrocyte.
1989
Formation of disulfide-linked oligomers of acetylcholine receptor in membrane from Torpedo electric tissue
1979
Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization
1986 Nature
Structural details of membrane-bound acetylcholine receptor from Tropedo marmorata.
1980 StandoutNobel
Change in state of phosphorylation of acetylcholine receptor during maturation of the electromotor synapse in Torpedo marmorata electric organ.
1981
β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization
1993 StandoutScienceNobel
Neural Science
2000 StandoutNobel
Phosphorylation of Ion channels
1985
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
1983 StandoutNatureNobel
Identification of exposed and buried determinants of the membrane-bound acetylcholine receptor from Torpedo californica
1981
Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.
1983
Molecular Forms and Hydrodynamic Properties of Acetylcholine Receptor from Electric Tissue
1981
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Developmental Regulation of Nicotinic Acetylcholine Receptors
1987
Role of acetylcholine receptor subunits in gating of the channel
1985 StandoutNatureNobel
Location of a δ-subunit region determining ion transport through the acetylcholine receptor channel
1986 StandoutNatureNobel
Modulation of acetylcholine receptor states by thiol modification
1980
Fluorescence energy transfer between cobra alpha-toxin molecules bound to the acetylcholine receptor.
1984
Organization of acetylcholine receptors in quick-frozen, deep-etched, and rotary-replicated Torpedo postsynaptic membrane.
1979
Insights into microtubule nucleation from the crystal structure of human γ-tubulin
2005 Nature
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Disulfide bond cross-linked dimer in acetylcholine receptor from Torpedo californica
1977
A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques.
1980
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
1987 StandoutNatureNobel
Peptide extraction by alkaline treatment is accompanied by rearrangement of the membrane‐bound acetylcholine receptor from torpedo marmorata
1980
Mapping of the cAMP-dependent phosphorylation sites on the acetylcholine receptor.
1986
Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy
2012
Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+channels of Aplysia sensory neurones in cell-free membrane patches
1985 StandoutNatureNobel
Immunospecific identification and three-dimensional structure of a membrane-bound acetylcholine receptor from Torpedo californica
1979
Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M r 95,000 receptor subunit is its own kinase
1983
Relative locations of the beta and delta chains of the acetylcholine receptor determined by electron microscopy of isolated receptor trimer.
1981
Receptor stability and channel conversion in the subsynaptic membrane of the developing mammalian neuromuscular junction
1980
MICROTUBULE POLYMERIZATION DYNAMICS
1997 Standout
Selective phosphorylation of the IgE receptor in antigen-stimulated rat mast cells.
1983
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein
2001 StandoutNobel
Acetylcholine Receptor: Complex of Homologous Subunits
1980 Science
Consequences of alkaline treatment for the ultrastructure of the acetylcholine-receptor-rich membranes from Torpedo marmorata electric organ.
1981
A Tunnel in the Large Ribosomal Subunit Revealed by Three-Dimensional Image Reconstruction
1987 StandoutScienceNobel
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
2002
Functional Equivalence of Monomeric and Dimeric Forms of Purified Acetylcholine Receptors from Torpedo californica in Reconstituted Lipid Vesicles
1980
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides.
1979
Three-Dimensional Structure of Cholera Toxin Penetrating a Lipid Membrane
1988 StandoutScienceNobel
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
1988 StandoutNatureNobel
Three-dimensional structure determination by electron microscopy of two-dimensional crystals
1982 StandoutNobel
Phosphorylation of the nicotinic acetylcholine receptor by an endogenous tyrosine-specific protein kinase.
1984
Crystalline arrays of membrane-bound acetylcholine receptor.
1981
Dimeric arrangement and structure of the membrane-bound acetylcholine receptor studied by electron microscopy.
1982 StandoutNobel
Forskolin increases the rate of acetylcholine receptor desensitization at rat soleus endplates.
1986
A voltage-gated anion channel from the electric organ of Torpedo californica.
1979
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor
1986 StandoutNatureNobel
Quaternary structure of the acetylcholine receptor
1985 Nature
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Co-translational membrane integration of calcium pump protein without signal sequence cleavage
1981 StandoutNatureNobel
Works of André Sobel being referenced
The Stathmin/Tubulin Interaction in Vitro
1997
A single amino acid difference distinguishes the human and the rat sequences of stathmin, a ubiquitous intracellular phosphoprotein associated with cell regulations
1990
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
2004 StandoutNature
Structural basis for the regulation of tubulin by vinblastine
2005 Nature
The phosphorylation of stathmin by MAP kinase
1993
Stathmin: a relay phosphoprotein for multiple signal transduction?
1991
Stathmin Family Proteins Display Specific Molecular and Tubulin Binding Properties
2001
The 4 Å X-Ray Structure of a Tubulin:Stathmin-like Domain Complex
2000
In vitro phosphorylation of the acetylcholine receptor
1977 Nature
Stathmin: A Tubulin-Sequestering Protein Which Forms a Ternary T2S Complex with Two Tubulin Molecules
1997
Reconstitution of a functional acetylcholine regulator under defined conditions
1979
Interaction of the Acetylcholine (Nicotinic) Receptor Protein from Torpedo marmorata Electric Organ with Monolayers of Pure Lipids
1978
The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network
1998
N-Terminal Stathmin-like Peptides Bind Tubulin and Impede Microtubule Assembly
2005
Reconstitution of a Functional Acetylcholine Receptor
1980
Selective labelling by [3H]trimethisoquin azide of polypeptide chains present in acetylcholine receptor‐rich membranes from Torpedo marmorata
1980
A morphological study of the cholinergic receptor protein from Torpedo marmorata in its membrane environment and in its detergent-extracted purified form
1978
Purification and Characterization of the Cholinergic Receptor Protein in its Membrane-Bound and Detergent-Soluble Forms from the Electric Organ of Torpedo marmorata
1977
Large‐Scale Purification of the Acetylcholine‐Receptor Protein in Its Membrane‐Bound and Detergent‐Extracted Forms from Torpedo marmorata Electric Organ
1977
Serine 16 of Stathmin as a Cytosolic Target for Ca2+/Calmodulin-Dependent Kinase II After CD2 Triggering of Human T Lymphocytes
1998