Standout Papers
Citation Impact
Citing Papers
RGS-PX1, a GAP for Gα s and Sorting Nexin in Vesicular Trafficking
2001 Science
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
Similar Structures and Shared Switch Mechanisms of the β2-Adrenoceptor and the Parathyroid Hormone Receptor
1999
Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ
2013 Standout
A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms
2008 StandoutNobel
Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets
2011
Regulatory GTPases
1995
Mechanochemistry: opportunities for new and cleaner synthesis
2011 Standout
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
GTPase activation of elongation factor EF‐Tu by the ribosome during decoding
2009 StandoutNobel
Molecular Dynamics Analysis of Structural Factors Influencing Back Door Pi Release in Myosin
2004
A Novel Gαq/11-selective Inhibitor
2004
End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation
2013
Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy
2008 StandoutNobel
Structural insights into cognate versus near‐cognate discrimination during decoding
2011 StandoutNobel
Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights
2007
An improved hydrogen bond potential: Impact on medium resolution protein structures
2002
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Trafficking Patterns of β-Arrestin and G Protein-coupled Receptors Determined by the Kinetics of β-Arrestin Deubiquitination
2003 StandoutNobel
An Orientation-dependent Hydrogen Bonding Potential Improves Prediction of Specificity and Structure for Proteins and Protein–Protein Complexes
2003 StandoutNobel
The Importance of Structural Transitions of the Switch II Region for the Functions of Elongation Factor Tu on the Ribosome
2001
Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits
2007 StandoutNobel
Mesoporous Materials for Drug Delivery
2007 Standout
The Conformation of Bound GMPPNP Suggests a Mechanism for Gating the Active Site of the SRP GTPase
2001
Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP.
1999
Seven-transmembrane receptors
2002 StandoutNobel
Sequential Binding of Agonists to the β2 Adrenoceptor
2003 StandoutNobel
Dynamics of the Upper 50-kDa Domain of Myosin V Examined with Fluorescence Resonance Energy Transfer
2005 StandoutNobel
GTP Hydrolysis Mechanism of Ras-like GTPases
2004
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits
1996 Nobel
Mutations in GNA11 in Uveal Melanoma
2010 Standout
Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis
1997 Nobel
Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins
1995 StandoutNobel
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase
2006 StandoutNobel
Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome
2010 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Close agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculations
2004 StandoutNobel
3d Transition Metals for C–H Activation
2018 Standout
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome
2011 StandoutNobel
Vanadium in Modern Organic Synthesis
1997
Biological Phosphoryl-Transfer Reactions: Understanding Mechanism and Catalysis
2011
On the Mechanism of Hydrolysis of Phosphate Monoesters Dianions in Solutions and Proteins
2006 StandoutNobel
Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
2009 StandoutNobel
Analyzing Free Energy Relationships for Proton Translocations in Enzymes: Carbonic Anhydrase Revisited
2004 StandoutNobel
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Phosphate Ester Hydrolysis in Aqueous Solution: Associative versus Dissociative Mechanisms
1998 StandoutNobel
Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Mechanism of Molybdenum Nitrogenase
1996 Standout
fw2.2 : A Quantitative Trait Locus Key to the Evolution of Tomato Fruit Size
2000 StandoutScience
Vanadium(II) complexes as efficient reagents for direct construction of asymmetric quaternary carbons from carbonyl compounds
1995
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
Trajectories of the ribosome as a Brownian nanomachine
2014 StandoutNobel
Solid-State NMR Study of Ibuprofen Confined in MCM-41 Material
2006
Addressing Open Questions about Phosphate Hydrolysis Pathways by Careful Free Energy Mapping
2012 StandoutNobel
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation Free Energies
2008 StandoutNobel
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex
2012 StandoutNobel
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation
2011 StandoutNobel
Mechanisms of signaling and related enzymes
1997
GTPase-Activating Proteins for Heterotrimeric G Proteins: Regulators of G Protein Signaling (RGS) and RGS-Like Proteins
2000
Mechanisms of signaling and related enzymes
1997
Structural Insights Into the Signal Recognition Particle
2004 StandoutNobel
On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution
2008 StandoutNobel
Stereoselective Pinacol Coupling in Aqueous Media
1996
G PROTEIN MECHANISMS: Insights from Structural Analysis
1997
G proteins, effectors and GAPs: structure and mechanism
1997
A Subclass of Ras Proteins That Regulate the Degradation of IκB
2000 Science
Structural flexibility of the Gαs α-helical domain in the β 2 -adrenoceptor Gs complex
2011 StandoutNobel
How Does GAP Catalyze the GTPase Reaction of Ras?: A Computer Simulation Study
2000 StandoutNobel
Formation and Characterization of Crystals Containing a Pleuromutilin Derivative, Succinic Acid and Water
2008
Works of Andre Raw being referenced
Quality by Design: Concepts for ANDAs
2008
Regulatory considerations of pharmaceutical solid polymorphism in Abbreviated New Drug Applications (ANDAs)
2003
Structure of the GDP–Pi complex of Gly203→Ala Giα1: a mimic of the ternary product complex of Gα-catalyzed GTP hydrolysis
1996 Nobel
Mechanism of GTP hydrolysis by G-protein alpha subunits.
1994 StandoutNobel
Synthesis of cis-1,2-cyclobutanediols via intramolecular pinacol coupling of 4-oxo aldehydes
1991
Structural and Biochemical Characterization of the GTPγS-, GDP·Pi-, and GDP-Bound Forms of a GTPase-Deficient Gly42 → Val Mutant of Giα1
1997 Nobel