Citation Impact
Citing Papers
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Qualitative and quantitative abnormalities in splenic dendritic cell populations in NOD mice
2004
Human CD1-restricted T cell recognition of lipids from pollens
2005
CD1d-dependent Activation of NKT Cells Aggravates Atherosclerosis
2004
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo
2005
Modulation of CD1d-restricted NKT cell responses by using N- acyl variants of α-galactosylceramides
2005
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
Glycolipid antigen induces long-term natural killer T cell anergy in mice
2005
Distinct Cytokine Profiles of Neonatal Natural Killer T Cells after Expansion with Subsets of Dendritic Cells
2001
Understanding autoimmune diabetes: insights from mouse models
2002
CD1d-restricted mouse Vα14 and human Vα24 T cells: lymphocytes of innate immunity
2000
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature
The Interleukin-4 Enhancer CNS-2 Is Regulated by Notch Signals and Controls Initial Expression in NKT Cells and Memory-Type CD4 T Cells
2006 StandoutNobel
Testing the NKT cell hypothesis of human IDDM pathogenesis
2002
Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice
2003
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD
1997
Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes
1998 Nature
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
The many paths to asthma: phenotype shaped by innate and adaptive immunity
2010
Extravascular T-cell recruitment requires initiation begun by Vα14+ NKT cells and B-1 B cells
2004
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
2003
The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice
2001
Regulatory T Cells
2000 StandoutNobel
Innate immunity conferred by toll‐like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal–induced inflammation
2005
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
CD1d deficiency exacerbates inflammatory dermatitis in MRL‐lpr/lpr mice
2004
Prolonged IFN-γ–producing NKT response induced with α-galactosylceramide–loaded DCs
2002 StandoutNobel
Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer
2002
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
2010
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis
1999
Gene expression in NKT cells: defining a functionally distinct CD1d-restricted T cell subset
2001
Animal models of autoimmunity and their relevance to human diseases
2000 StandoutNobel
NKT cells: what's in a name?
2004
The third function of the thymus
2000
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Multiple immuno-regulatory defects in type-1 diabetes
2002
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells
2002
Mechanisms of inflammation in gout
2005
The PD‐1 pathway in tolerance and autoimmunity
2010 Standout
Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted γδ T cells
2006
Naturally anergic and suppressive CD25+CD4+ T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
2000 StandoutNobel
B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes
2000 Standout
Interactions between Mycoplasmas and the Immune System
1989
CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance
2002
Asthma phenotypes: the evolution from clinical to molecular approaches
2012 Standout
Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus
2003
CD4+ Invariant T-Cell–Receptor+ Natural Killer T Cells in Bronchial Asthma
2006
NKT Cells Inhibit the Onset of Diabetes by Impairing the Development of Pathogenic T Cells Specific for Pancreatic β Cells
2002
The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells
2004
QUANTIFICATION OF MURINE CYTOKINE mRNAs USING REAL TIME QUANTITATIVE REVERSE TRANSCRIPTASE PCR
1999
Regulatory Natural Killer T Cells Protect against Spontaneous and Recurrent Type 1 Diabetes
2002
NKT cells: facts, functions and fallacies
2000
Regulatory T cells in the control of immune pathology
2001
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
2008
Control of immune pathology by regulatory T cells
1998
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
2009 Standout
NKT cells derive from double-positive thymocytes that are positively selected by CD1d
2001
Genetic Control of Diabetes Progression
1997
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
Positive and Negative Selection of T Cells
2003
The Regulatory Role of Vα14 NKT Cells in Innate and Acquired Immune Response
2003
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
CD161 (NKR-P1A) Costimulation of CD1d-dependent Activation of Human T Cells Expressing Invariant Vα24JαQ T Cell Receptor α Chains
1998
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Haploinsufficiency of mTR results in defects in telomere elongation
2002 StandoutNobel
Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site
1999
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-γ in IL-12/IL-18-stimulated mouse macrophage populations
2004
Expansion and Hyperactivity of CD1d-Restricted NKT Cells during the Progression of Systemic Lupus Erythematosus in (New Zealand Black × New Zealand White)F1 Mice
2005
Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis
1996
Granulocyte-macrophage colony-stimulating factor augmentation of T-cell receptor-dependent and T-cell receptor-independent thymocyte proliferation
1994
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets
2001
The Biology of NKT Cells
2006 Standout
Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus
2003
The Vα14 NKT Cell TCR Exhibits High-Affinity Binding to a Glycolipid/CD1d Complex
2002
Expression of CD1d Under the Control of a MHC Class Ia Promoter Skews the Development of NKT Cells, But Not CD8+ T Cells
2003
Regulatory T Cells in Autoimmmunity
2000
Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway
2000
Activated NKT Cells Inhibit Autoimmune Diabetes through Tolerogenic Recruitment of Dendritic Cells to Pancreatic Lymph Nodes
2005
Sequential production of interferon-γ by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide
2002
Hepatitis B vaccination for patients with chronic renal failure
2004
Dynamics of Pathogenic and Suppressor T Cells in Autoimmune Diabetes Development
2003
Induction of Regulatory Properties in Dendritic Cells by Vα14 NKT Cells
2005
Cutting Edge: NKT Cell Development Is Selectively Impaired in Fyn- Deficient Mice
1999
Activation of Natural Killer T Cells by α-Galactosylceramide Rapidly Induces the Full Maturation of Dendritic Cells In Vivo and Thereby Acts as an Adjuvant for Combined CD4 and CD8 T Cell Immunity to a Coadministered Protein
2003 StandoutNobel
Activation of Natural Killer T Cells Potentiates or Prevents Experimental Autoimmune Encephalomyelitis
2001
Loss of IFN-γ Production by Invariant NK T Cells in Advanced Cancer
2001
In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes
2004
Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide
2001
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers
2000
Cyclophosphamide-Induced Type-1 Diabetes in the NOD Mouse Is Associated with a Reduction of CD4+CD25+Foxp3+ Regulatory T Cells
2006
CD1d-Specific NK1.1+ T Cells with a Transgenic Variant TCR
2000
Contact with Thymic Epithelial Cells as a Prerequisite for Cytokine-Enhanced Human Immunodeficiency Virus Type 1 Replication in Thymocytes
1998 StandoutNobel
Spiralin, a mycoplasmal membrane lipoprotein, induces T-cell-independent B-cell blastogenesis and secretion of proinflammatory cytokines
1997 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Testing the NKT cell hypothesis of human IDDM pathogenesis
2002
Multiple immuno-regulatory defects in type-1 diabetes
2002
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
CD1d-restricted Recognition of Synthetic Glycolipid Antigens by Human Natural Killer T Cells
1998
A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors.
2002
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Natural Killer T Cell Activation Protects Mice Against Experimental Autoimmune Encephalomyelitis
2001
Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+CD8−CD3+Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7
1999 StandoutNobel
Role of CD1d in Coxsackievirus B3-Induced Myocarditis
2003
A Natural Killer T (NKT) Cell Developmental Pathway Involving a Thymus-dependent NK1.1−CD4+ CD1d-dependent Precursor Stage
2002
Isolation, Structure Elucidation, and Synthesis of a Macrophage Stimulatory Lipopeptide from Mycoplasma fermentans Acting at Picomolar Concentration
1997
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Critical contribution of IFN-gamma and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of alpha-galactosylceramide.
2001
MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function
1997
Quantitative and Qualitative Differences in the In Vivo Response of NKT Cells to Distinct α- and β-Anomeric Glycolipids
2004
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution
1998
THE NOD MOUSE: A Model of Immune Dysregulation
2004
Glycolipid activation of invariant T cell receptor + NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4 + T cells
2006
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Invariant NKT Cells Exacerbate Type 1 Diabetes Induced by CD8 T Cells
2005
Production of Profibrotic Cytokines by Invariant NKT Cells Characterizes Cirrhosis Progression in Chronic Viral Hepatitis
2004
High-Level Replication of Human Immunodeficiency Virus in Thymocytes Requires NF-κB Activation through Interaction with Thymic Epithelial Cells
1999 StandoutNobel
Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− Thymocytes
1999
The Role of Innate Immunity in Autoimmunity
2004
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Failure to Censor Forbidden Clones of CD4 T Cells in Autoimmune Diabetes
2002
The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells
2004
CD4+ T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti–Myelin Basic Protein T Cell Receptor Transgenic Mice
1998 Nobel
CD1d on Myeloid Dendritic Cells Stimulates Cytokine Secretion from and Cytolytic Activity of Vα24JαQ T Cells: A Feedback Mechanism for Immune Regulation
2000
Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes
1998
CD1: Antigen Presentation and T Cell Function
2004
A Critical Role for Natural Killer T Cells in Immunosurveillance of Methylcholanthrene-induced Sarcomas
2002
Nonredundant Roles for CD1d-restricted Natural Killer T Cells and Conventional CD4+ T Cells in the Induction of Immunoglobulin E Antibodies in Response to Interleukin 18 Treatment of Mice
2003
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
1999 StandoutNobel
NKT Cell Stimulation with Glycolipid Antigen In Vivo: Costimulation-Dependent Expansion, Bim-Dependent Contraction, and Hyporesponsiveness to Further Antigenic Challenge
2005
How defects in central tolerance impinge on a deficiency in regulatory T cells
2005
Cd1-Restricted Nk T Cells Protect Nonobese Diabetic Mice from Developing Diabetes
2001
Distinct Roles of Dendritic Cells and B Cells in Va14Ja18 Natural T Cell Activation In Vivo
2005
Distinct Subsets of CD1d-restricted T Cells Recognize Self-antigens Loaded in Different Cellular Compartments
1999
Requirements for CD1d Recognition by Human Invariant Vα24+ CD4−CD8− T Cells
1997
Activating Immunity in the Liver. I. Liver Dendritic Cells (but Not Hepatocytes) Are Potent Activators of IFN-γ Release by Liver NKT Cells
2001
CD1d-expressing Dendritic Cells but Not Thymic Epithelial Cells Can Mediate Negative Selection of NKT Cells
2003
Genetic Control of NKT Cell Numbers Maps to Major Diabetes and Lupus Loci
2003
Mycoplasma membrane lipoproteins induced proinflammatory cytokines by a mechanism distinct from that of lipopolysaccharide
1996
Works of André Herbelin being referenced
Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate "active tolerance" in the nonobese diabetic mouse.
1998
A Distinct IL-18-Induced Pathway to Fully Activate NK T Lymphocytes Independently from TCR Engagement
1999
Early quantitative and functional deficiency of NK1+‐like thymocytes in the NOD mouse
1996
α‐Galactosylceramide‐induced iNKT cells suppress experimental allergic asthma in sensitized mice: Role of IFN‐γ
2005
Autoimmune diabetes: How many steps for one disease?
1997
Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
2001
Inhibition and prevention of monosodium urate monohydrate crystal–induced acute inflammation in vivo by transforming growth factor β1
1996
Ligand-activated natural killer T lymphocytes promptly produce IL-3 and GM-CSF in vivo: relevance to peripheral myeloid recruitment
2002
NKT Cell-Plasmacytoid Dendritic Cell Cooperation via OX40 Controls Viral Infection in a Tissue-Specific Manner
2009
IL-7 reverses NK1+ Tcell-defective IL-4 production in the non-obese diabetic mouse
1996
NK1.1+ T cells from IL-7-deficient mice have a normal distribution and selection but exhibit impaired cytokine production
1996
The pro‐Th2 cytokine IL‐33 directly interacts with invariant NKT and NK cells to induce IFN‐γ production
2009
Characterization of thymic cell subpopulations involved in IL-1- or GM-CSF-induced IL-6 production.
1992
IL-7 is requisite for IL-1-induced thymocyte proliferation. Involvement of IL-7 in the synergistic effects of granulocyte-macrophage colony-stimulating factor or tumor necrosis factor with IL-1.
1992
Cutting Edge: Invariant Vα14 NKT Cells Are Required for Allergen-Induced Airway Inflammation and Hyperreactivity in an Experimental Asthma Model
2003
Cutting Edge: Vα14-Jα281 NKT Cells Naturally Regulate Experimental Autoimmune Encephalomyelitis in Nonobese Diabetic Mice
2002
Genetic and Functional Analysis of theNkt1Locus Using Congenic NOD Mice
2006
MHC class I-selected CD4-CD8-TCR-alpha beta+ T cells are a potential source of IL-4 during primary immune response.
1995
IL-18 Enhances IL-4 Production by Ligand-Activated NKT Lymphocytes: A Pro-Th2 Effect of IL-18 Exerted Through NKT Cells
2001
Functional bioassays for B cell growth factors using polyclonally activated murine spleen B cells.
1989
Interleukin 7 induces preferential expansion of V beta 8.2+CD4-8- and V beta 8.2+CD4+8- murine thymocytes positively selected by class I molecules.
1994
Protection Against Diabetes and Improved NK/NKT Cell Performance in NOD.NK1.1 Mice Congenic at the NK Complex
2001
Early defect of immunoregulatory T cells in autoimmune diabetes.
1996
Endogenous granulocyte-macrophage colony-stimulating factor is involved in IL-1- and IL-7-induced murine thymocyte proliferation.
1994
Mycoplasma arginini TUH-14 membrane lipoproteins induce production of interleukin-1, interleukin-6, and tumor necrosis factor alpha by human monocytes
1994
CD11c+ Eosinophils in the Murine Thymus: Developmental Regulation and Recruitment upon MHC Class I-Restricted Thymocyte Deletion
2000
A natural protective function of invariant NKT cells in a mouse model of innate‐cell‐driven lung inflammation
2010
A Subset of NKT Cells That Lacks the NK1.1 Marker, Expresses CD1d Molecules, and Autopresents the α-Galactosylceramide Antigen
2000
Mature Mainstream TCRαβ+CD4+ Thymocytes Expressing L-Selectin Mediate “Active Tolerance” in the Nonobese Diabetic Mouse
1998
Immune deficiency of the uremic patient.
1990
IL-7 Up-Regulates IL-4 Production by Splenic NK1.1+ and NK1.1− MHC Class I-Like/CD1-Dependent CD4+ T Cells
1999
Fas/Fas Ligand Interactions Promote Activation-Induced Cell Death of NK T Lymphocytes
2000