Citation Impact
Citing Papers
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Cytotoxicity by tumor necrosis factor is mediated by both p55 and p70 receptors
1993
Cutting Edge: Functional Interactions Between Toll-Like Receptor (TLR) 2 and TLR1 or TLR6 in Response to Phenol-Soluble Modulin
2001
Toll receptors and pathogen resistance
2003
Recognition of Gram-negative bacteria and endotoxin by the innate immune system
1999
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
1995 Standout
Ribosome-inactivating proteins from plants
1993
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
2006 Standout
Lipopolysaccharide Is in Close Proximity to Each of the Proteins in Its Membrane Receptor Complex
2001
The Hallmarks of Cancer
2000 Standout
Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
2007
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages
2018
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
CD36 is a sensor of diacylglycerides
2005 StandoutNatureNobel
Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products
1999
Expression of both TNF-α receptor subtypes is essential for optimal skin tumour development
2003
Apo2L/TRAIL and its death and decoy receptors
2003
Naive and memory B cells in T-cell-dependent and T-independent responses
2001
Enzymatically Deacylated Lipopolysaccharide (LPS) Can Antagonize LPS at Multiple Sites in the LPS Recognition Pathway
1995
The Ways of Endocytosis
1989
Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes
1999
Cell-mediated cytotoxicity
1993 StandoutNobel
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1998 Nature
Toll-like receptors: critical proteins linking innate and acquired immunity
2001 Standout
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy
2003
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
1993
Toll-like receptors and innate immunity
2009
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice
1994 Nature
Cancer-related inflammation
2008 StandoutNature
TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways
1996 Standout
Combinatorial Signal Perception in the BMP Pathway
2017
Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling
2005
Annexin VI is required for budding of clathrin-coated pits
1992 StandoutNobel
E5531, a synthetic non‐toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide
1999
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
2002
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
1998 Nature
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor.
1990 StandoutNobel
Toll-Like Receptors
2003 Standout
Interleukin-10 and the immune response against cancer: a counterpoint
2005
T Cell-Independent Antigens Type 2
1995
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.
1995
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40
1995 Science
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
1998
Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein.
1995
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.
1994
Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.
1995
Regulation of Toll-Like Receptor 2 Expression by Macrophages FollowingMycobacterium aviumInfection
2000
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact
1997
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.
1989
Lipopolysaccharides fromLegionellaandRhizobiumstimulate mouse bone marrow granulocytes via Toll-like receptor 2
2002
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
2003
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
1991 Standout
NFκB and Sp1 Elements Are Necessary for Maximal Transcription of Toll-like Receptor 2 Induced byMycobacterium avium
2001
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
2000 Standout
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
2007
Toll-Like Receptor 2 Is Required for Innate, But Not Acquired, Host Defense to Borrelia burgdorferi
2002
Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent
2002
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2
2000
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Interleukin 12: A key modulator of immune function
1994
Chlamydia pneumoniae and Chlamydial Heat Shock Protein 60 Stimulate Proliferation of Human Vascular Smooth Muscle Cells via Toll-Like Receptor 4 and p44/p42 Mitogen-Activated Protein Kinase Activation
2001
Neutrophil Extracellular Traps Kill Bacteria
2004 StandoutScience
Lipopolysaccharide-Induced IL-18 Secretion from Murine Kupffer Cells Independently of Myeloid Differentiation Factor 88 That Is Critically Involved in Induction of Production of IL-12 and IL-1β
2001
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36
2008
Effects of cytoplasmic acidification on clathrin lattice morphology.
1989
Induction of Cross-Tolerance by Lipopolysaccharide and Highly Purified Lipoteichoic Acid Via Different Toll-Like Receptors Independent of Paracrine Mediators
2001
Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice
1996
Protective Roles of Mast Cells Against Enterobacterial Infection Are Mediated by Toll-Like Receptor 4
2001
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
LPS-binding proteins and receptors
1998
De novo design of protein logic gates
2020 StandoutScienceNobel
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Tissue Expression of Human Toll-Like Receptors and Differential Regulation of Toll-Like Receptor mRNAs in Leukocytes in Response to Microbes, Their Products, and Cytokines
2002
Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span
2003
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Works of Anders Sundan being referenced
Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B
2015
Toll-like receptors mediate proliferation and survival of multiple myeloma cells
2006
Soluble CD14 from urine copurifies with a potent inducer of cytokines
1994
REGULATION OF APO-2 LIGAND/TRAIL EXPRESSION IN NK CELLS—INVOLVEMENT IN NK CELL-MEDIATED CYTOTOXICITY
1999
Isolation andin vitro, expression of the ricin A-chain gene: effect of deletions on biological activity
1989
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells
2011
Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88
2004
Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities
1994
REGULATION OF FAS AND FAS-LIGAND EXPRESSION IN NK CELLS BY CYTOKINES AND THE INVOLVEMENT OF FAS-LIGAND IN NK/LAK CELL-MEDIATED CYTOTOXICITY
1997
The involvement of CD14 in stimulation of cytokine production by uronic acid polymers
1993
Distinct Roles of the Two Tumor Necrosis Factor (TNF) Receptors in Modulating TNF and Lymphotoxin α Effects
1996
Gene expression and secretion of cytokines and cytokine receptors from highly purified CD56+ natural killer cells stimulated with interleukin‐2, interleukin‐7 and interleukin‐12
1993
Elevated Levels of Serum-Soluble CD14 in Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Correlation to Disease Progression and Clinical Events
1998
Differential expression of Toll-like receptor 2 in human cells
2001
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway.
1982
Human Toll-Like Receptor 2 Mediates Monocyte Activation byListeria monocytogenes, But Not by Group B Streptococci or Lipopolysaccharide
2000
Elevated Levels of Serum-Soluble CD14 in Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Correlation to Disease Progression and Clinical Events
1998
Tumor necrosis factor receptor p75 mediates cell-specific activation of nuclear factor kappa B and induction of human cytomegalovirus enhancer.
1994
Binding and regulation of cellular functions by monoclonal antibodies against human tumor necrosis factor receptors.
1990
Inflammatory Response After Open Heart Surgery
2002
Synergistic effects of interleukin 4 and interleukin 12 on NK cell proliferation
1993
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
1985
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss
2017
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells
1985
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments.
1984
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
1983
Direct molecular cloning and expression of two distinct abrin A-chains.
1991
Soluble CD14 participates in the response of cells to lipopolysaccharide.
1992