Citation Impact
Citing Papers
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence
2021
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Mice with hyper-long telomeres show less metabolic aging and longer lifespans
2019
Hallmarks of Cancer: The Next Generation
2011 Standout
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
2012
Linking functional decline of telomeres, mitochondria and stem cells during ageing
2010 Nature
The DNA-damage response in human biology and disease
2009 StandoutNature
Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing
2013 StandoutNobel
Combinatory approaches prevent preterm birth profoundly exacerbated by gene-environment interactions
2013
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins
2015
Senescence-messaging secretome: SMS-ing cellular stress
2009
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
2011
Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
2012
Cellular senescence: when bad things happen to good cells
2007 Standout
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Telomeres: history, health, and hallmarks of aging
2021
The genetics of ageing
2010 StandoutNature
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status
2010
p53 — a Jack of all trades but master of none
2009
The emerging role of lncRNAs in cancer
2015 Standout
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
Cellular Senescence in Cancer and Aging
2007 Standout
Long Noncoding RNAs in Cancer Pathways
2016 Standout
Increased p53 activity does not accelerate telomere‐driven ageing
2006
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models
2021
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
2009
OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research
2011
Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage
2015
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
The Epigenomics of Cancer
2007 Standout
Axis of ageing: telomeres, p53 and mitochondria
2012
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Models, mechanisms and clinical evidence for cancer dormancy
2007
New plays in the p53 theater
2010
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
2009
How stem cells age and why this makes us grow old
2007
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Progeria syndromes and ageing: what is the connection?
2010
Age to survive: DNA damage and aging
2008
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
Metabolic Regulation by p53 Family Members
2013
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
2012
Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis
2011
Stems Cells and the Pathways to Aging and Cancer
2008
p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice
2009
The common biology of cancer and ageing
2007 Nature
Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence
2009
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
2010 Nature
Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2
2012
Two faces of p53: aging and tumor suppression
2007
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
EMT: 2016
2016 Standout
Emerging models and paradigms for stem cell ageing
2011
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
2006 Nature
Angiocrine functions of organ-specific endothelial cells
2016 Nature
Modulation of intracellular ROS levels by TIGAR controls autophagy
2009
Role of shelterin in cancer and aging
2010
The Inflammasomes
2010 Standout
The role of senescent cells in ageing
2014 StandoutNature
The telomerase activator TA‐65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
2011
Clonal evolution in cancer
2012 StandoutNature
The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity
2015
Nuclear envelope alterations generate an aging‐like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
2010
The Hallmarks of Aging
2013 Standout
eEF1A Mediates the Nuclear Export of SNAG-Containing Proteins via the Exportin5-Aminoacyl-tRNA Complex
2013
The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity
2012
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
DNA damage response and cellular senescence in tissues of aging mice
2009
The role of telomeres and telomerase in stem cell aging
2010
The Regulation of INK4/ARF in Cancer and Aging
2006
Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
2012
Frailty in elderly people
2013 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
2008
p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice
2013
Feedback between p21 and reactive oxygen production is necessary for cell senescence
2010
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Maternally Expressed Gene 3, an Imprinted Noncoding RNA Gene, Is Associated with Meningioma Pathogenesis and Progression
2010
Epithelial-mesenchymal transitions: insights from development
2012
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Biological mechanisms of aging predict age‐related disease co‐occurrence in patients
2022
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Four faces of cellular senescence
2011 Standout
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Stress-Induced Phosphorylation of PACT Reduces Its Interaction with TRBP and Leads to PKR Activation
2011
Preterm labor: One syndrome, many causes
2014 StandoutScience
Mouse Models to Disentangle the Hallmarks of Human Aging
2018
Impact of Protein Kinase PKR in Cell Biology: from Antiviral to Antiproliferative Action
2006
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction
2021
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres
2018
Heightened uterine mammalian target of rapamycin complex 1 (mTORC1) signaling provokes preterm birth in mice
2011
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53
2009
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Works of Ander Matheu being referenced
Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis
2012
Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation
2011
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
2008
Regulation of the INK4a/ARF Locus by Histone Deacetylase Inhibitors
2005
Antiviral action of the tumor suppressor ARF
2006
Anti‐aging activity of the Ink4/Arf locus
2009
Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging
2004
Delayed ageing through damage protection by the Arf/p53 pathway
2007 Nature
Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature
2014
Inactivation of Imprinted Genes Induced by Cellular Stress and Tumorigenesis
2005
Autophagy in stem cell aging
2017
The Arf/p53 Pathway in Cancer and Aging
2008