Citation Impact
Citing Papers
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Adenomatous polyposis coli‐deficient zebrafish are susceptible to digestive tract neoplasia
2006
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis
1999
Apc1638N: A mouse model for familial adenomatous polyposis–associated desmoid tumors and cutaneous cysts
1998
APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis
2000
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Probing p53 biological functions through the use of genetically engineered mouse models
2005
Molecular genetics of implantation in the mouse
1997
Efficient recovery of ENU-induced mutations from the zebrafish germline.
1994
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
1999
Inflammation and cancer
2002 StandoutNature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
A forward-genetic approach for analysis of the immune system
2003 StandoutNobel
TCF transcription factors: molecular switches in carcinogenesis
1999
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
2010 StandoutNature
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
2010
Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer
2005
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
1995
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Inducible in vivo genome editing with CRISPR-Cas9
2015
Positional Cloning of the Mouse Circadian Gene
1997
Alleles of the APC gene: An attenuated form of familial polyposis
1993
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
The Hallmarks of Cancer
2000 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Gene function in mouse embryogenesis: get set for gastrulation
2007
Mechanisms of carcinogenesis and the mutant mouse
1996
Tracing Cell Fates in Human Colorectal Tumors from Somatic Microsatellite Mutations
1998
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
2001 Nature
Mutations in the APC tumour suppressor gene cause chromosomal instability
2001
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling
2002
Fibre-supplemented foods may damage your health
1996
Linking Colorectal Cancer to Wnt Signaling
2000
Mutations of theAPC adenomatous polyposis coli) gene
1993
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
1996 Standout
Genetic predisposition to colorectal cancer
2004
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Genes and development: molecular and logical themes.
1990 StandoutNobel
Smad3 Mutant Mice Develop Metastatic Colorectal Cancer
1998
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
1993
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
2005 Nature
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
Piroxicam and Acarbose as Chemopreventive Agents for Spontaneous Intestinal Adenomas in APC Gene 1309 Knockout Mice
1998
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
EphB receptor activity suppresses colorectal cancer progression
2005 Nature
Protease sensors for bioimaging
2003
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
2009
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
1993
Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene
1999
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
2009 StandoutNobel
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
1998
Of fin and fur: mutational analysis of vertebrate embryonic development.
1992
β-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds
2002 Standout
Mammalian DNA Mismatch Repair
1999
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
The Von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer
2004 StandoutNobel
APC mutations in colorectal tumors with mismatch repair deficiency.
1996
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.
1995
Nonsteroidal Anti-Inflammatory Drugs and Cancer Prevention
2000
Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
2001 Standout
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
2002
Of Flies and Fishes
1994 StandoutScienceNobel
Antioncogenes and human cancer.
1993
Simple and efficient production of embryonic stem cell-embryo chimeras by coculture.
1993 StandoutNobel
Wnt signaling and cancer
2000 Standout
Independent Photoreceptive Circadian Clocks Throughout Drosophila
1997 StandoutScienceNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Innate Immune Inflammatory Response against Enteric Bacteria Helicobacter hepaticus Induces Mammary Adenocarcinoma in Mice
2006
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene.
1995
Evidence against dominant negative mechanisms of intestinal polyp formation by Apc gene mutations.
1995
A Novel Mutation in CD83 Results in the Development of a Unique Population of CD4+ T Cells
2004 StandoutNobel
The Mouse Clock Mutation Behaves as an Antimorph and Maps Within the W19H Deletion, Distal of Kit
1997
beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex.
1996 StandoutNobel
Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin
1995 Science
Mutation ofPten/Mmac1in mice causes neoplasia in multiple organ systems
1999
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage
2004
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
2008
APC binds to the novel protein EB1.
1995
Vitamin B 2 -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
1998 StandoutNobel
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
The chromosomal distribution of mouse odorant receptor genes.
1996 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects
1993 Science
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2
1999 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
1995
Pathologic progression of autochthonous prostate cancer in the TRAMP model
1999
Apoptosis and APC in colorectal tumorigenesis.
1996
Synergy Between Tumor Suppressor APC and the β-Catenin-Tcf4 Target Tcf1
1999 Science
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis.
1996
Association of the APC Tumor Suppressor Protein with Catenins
1993 Science
Works of Amy Moser being referenced
Studies of neoplasia in the Min mouse1C57BL/6J Min/+ mice are available worldwide from The Jackson Laboratory, Bar Harbor, ME 04609, USA.1
1997
The Adenomatous Polyposis Coli Gene of the Mouse in Development and Neoplasia
1994
ApcMin: A mouse model for intestinal and mammary tumorigenesis
1995
Homozygosity for the Minallele of Apc results in disruption of mouse development prior to gastrulation
1995
Mapping of Multiple Intestinal Neoplasia (Min) to Proximal Chromosome 18 of the Mouse
1993
Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam.
1996
Loss of Apc+ in intestinal adenomas from Min mice.
1994
The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system.
1992
Genetic Evaluation of Candidate Genes for the Mom1 Modifier of Intestinal Neoplasia in Mice
1996
Mapping to molecular resolution in the T to H-2 region of the mouse genome with a nested set of meiotic recombinants.
1989
A Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse
1990 Science
Effects of ENU dosage on mouse strains
2000
Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia.
1993
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.
1993
Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status.
1997
N-ethyl-N-nitrosourea treatment of multiple intestinal neoplasia (Min) mice: age-related effects on the formation of intestinal adenomas, cystic crypts, and epidermoid cysts.
1995
Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene
1992 Science
Tumorigenesis in the multiple intestinal neoplasia mouse: Redundancy of negative regulators and specificity of modifiers
2000