Citation Impact
Citing Papers
Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis
2008
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma
2012
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
2007 StandoutScience
Extracellular HMGB1 as a Proinflammatory Cytokine
2004
Coregulation of Neurite Outgrowth and Cell Survival by Amphoterin and S100 Proteins through Receptor for Advanced Glycation End Products (RAGE) Activation
2000
In Skeletal Muscle Advanced Glycation End Products (AGEs) Inhibit Insulin Action and Induce the Formation of Multimolecular Complexes Including the Receptor for AGEs
2008
Purification and Characterization of Mouse Soluble Receptor for Advanced Glycation End Products (sRAGE)
2004
S100A7 and the progression of breast cancer
2004
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis
2005
RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response
2002
The intracrine hypothesis and intracellular peptide hormone action
2003
Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells
2005
HMGB1 is a potent trigger of arthritis
2004
Proteases in invasion: matrix metalloproteinases
2001
Necroptosis and its role in inflammation
2015 StandoutNature
Inflammatory links between obesity and metabolic disease
2011 Standout
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
The biology of the receptor for advanced glycation end products and its ligands
2000
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts
2001
Expression of receptors for advanced glycation end‐products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer
2001
Alarmins: awaiting a clinical response
2012
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
The biology of RAGE and its ligands: Uncovering mechanisms at the heart of diabetes and its complications
2007
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Receptor for Advanced Glycation End Products (RAGE) Signaling Induces CREB-dependent Chromogranin Expression during Neuronal Differentiation
2002
Cell death, BAX activation, and HMGB1 release during infection with Chlamydia
2004
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1
2004
Increased expression of HMGB1 is associated with poor prognosis in human bladder cancer
2012
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
2003
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
2002 StandoutNobel
HMGB1: guiding immunity from within
2005
Atherosclerosis and diabetes: The rage connection
2000
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
The grateful dead: damage‐associated molecular pattern molecules and reduction/oxidation regulate immunity
2007
Pattern Recognition Receptors and Inflammation
2010 Standout
Proteomic identification of differently expressed proteins responsible for osteoblast differentiation from human mesenchymal stem cells
2007
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
2001
Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke
2010
RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
2005
Severe Sepsis and Septic Shock
2013 Standout
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Regulation of monocyte migration by amphoterin (HMGB1)
2004
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism
2005
Osteoarthritis
2015 Standout
Inflammation and insulin resistance
2006 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Senescent cells as a source of inflammatory factors for tumor progression
2010
Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells
2005
Pathologies Involving the S100 Proteins and Rage
2007
Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function
2004
Central role of RAGE-dependent neointimal expansion in arterial restenosis
2003
RAGE (receptor for advanced glycation end products): a central player in the inflammatory response
2004
Down-regulation of Lysyl Oxidase-induced Tumorigenic Transformation in NRK-49F Cells Characterized by Constitutive Activation of Ras Proto-oncogene
2001
Targeting HMGB1 in inflammation
2009
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
2004
Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner
2003
High mobility group box chromosomal protein 1: A novel proinflammatory mediator in synovitis
2002
RAGE is the Major Receptor for the Proinflammatory Activity of HMGB1 in Rodent Macrophages
2005
Tempering the wrath of RAGE: An emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation
2009
Differential effects between amphoterin and advanced glycation end products on colon cancer cells
2003
The immunology of stroke: from mechanisms to translation
2011 Standout
Receptor for Advanced Glycation End Products Plays a More Important Role in Cellular Survival than in Neurite Outgrowth during Retinoic Acid-induced Differentiation of Neuroblastoma Cells
2002
Regulation of Vascular Endothelial Growth Factor Expression by Advanced Glycation End Products
2001
Hyaluronan synthesis and degradation in cartilage and bone
2007
HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers
2018
High mobility group box 1 protein, a cue for stem cell recruitment
2004
The receptor for advanced glycation end‐products (RAGE) directly binds to ERK by a D‐domain‐like docking site
2003
Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
2004
Origin and physiological roles of inflammation
2008 StandoutNature
Addicted to Death
2004
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
2005 Standout
The RAGE Axis and Endothelial Dysfunction: Maladaptive Roles in the Diabetic Vasculature and Beyond
2005
Oligomeric and Fibrillar Species of Amyloid-β Peptides Differentially Affect Neuronal Viability
2002 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Points of control in inflammation
2002 StandoutNature
Getting to the site of inflammation: the leukocyte adhesion cascade updated
2007 Standout
Idiopathic pulmonary fibrosis
2011 Standout
S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
2001 Standout
Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)
2008
Advanced glycation end-products: a review
2001 Standout
NEW EMBO MEMBERS' REVIEW: The double life of HMGB1 chromatin protein: architectural factor and extracellular signal
2001
Receptor for Advanced Glycation End Products Is Subjected to Protein Ectodomain Shedding by Metalloproteinases
2008
Hepatoma-derived Growth Factor Is a Neurotrophic Factor Harbored in the Nucleus
2004
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects
2003
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation
2011
Molecular Mechanisms of Amyloidosis
2003 Standout
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
2009 Standout
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Significant (re)location: how to use chromatin and/or abundant proteins as messages of life and death
2004
HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain
2003
Central role of RAGE-dependent neointimal expansion in arterial restenosis
2003
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Chronic Vascular Inflammation in Patients With Type 2 Diabetes
2005
Increased Expression of the DNA-Binding Cytokine HMGB1 in Human Atherosclerotic Lesions
2004
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-α and NF-κB
2005
Blockade of Late Stages of Autoimmune Diabetes by Inhibition of the Receptor for Advanced Glycation End Products
2004
Advanced Glycation End Products
2006 Standout
Early Release of HMGB-1 from Neurons after the Onset of Brain Ischemia
2007
Clinical Implications of Extracellular HMGA1 in Breast Cancer
2019
Cutting Edge: Extracellular High Mobility Group Box-1 Protein Is a Proangiogenic Cytokine
2006
Alternative splicing of the murine receptor for advanced glycation end‐products (RAGE) gene
2009
The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells
2001
Glycation, Inflammation, and RAGE
2003
Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis
2000
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins
2003
Activation of gene expression in human neutrophils by high mobility group box 1 protein
2003
Borna Disease Virus Phosphoprotein Binds a Neurite Outgrowth Factor, Amphoterin/HMG-1
2001
Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes
2005 Standout
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
2010
Rho GTPases and leucocyte-induced endothelial remodelling
2005
Oxidative Stress and Diabetic Complications
2010 Standout
RAGE Regulates the Metabolic and Inflammatory Response to High-Fat Feeding in Mice
2014
Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging
2020
Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells
2003
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
2001
HMGB1 and RAGE in Inflammation and Cancer
2010
RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
2009
Exogenous High-Mobility Group Box 1 Protein Induces Myocardial Regeneration After Infarction via Enhanced Cardiac C-Kit + Cell Proliferation and Differentiation
2005
Overexpression of high mobility group box 1 in gastrointestinal stromal tumors with KIT mutation.
2003
Mechanisms of Diabetic Complications
2013 Standout
Understanding RAGE, the receptor for advanced glycation end products
2005
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Geometric cues for directing the differentiation of mesenchymal stem cells
2010 Standout
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
2004 Standout
RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways
2004
Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis.
2002
Dual roles for HMGB1: DNA binding and cytokine
2001
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
2018 Standout
DAMPs, PAMPs and alarmins: all we need to know about danger
2006 Standout
Physiology of Microglia
2011 Standout
S100B binding to RAGE in microglia stimulates COX-2 expression
2006
RAGE Axis
2004
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
2001
Works of Amy Lu being referenced
PDGFRα reporter activity identifies periosteal progenitor cells critical for bone formation and fracture repair
2022
Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases
2000 Nature