Citation Impact

Citing Papers

Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
De novo design of a transmembrane Zn 2+ -transporting four-helix bundle
2014 Science
Computational design of a protein crystal
2012
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Generative models for graph-based protein design
2019
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
A statistical framework for analyzing deep mutational scanning data
2017
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core
2012
A De Novo Protein Binding Pair By Computational Design and Directed Evolution
2011 StandoutNobel
De novo designed peptides for biological applications
2011
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display
2009
Automated design of specificity in molecular recognition
2002
Probing Designability via a Generalized Model of Helical Bundle Geometry
2010
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
A de novo peptide hexamer with a mutable channel
2011
Optimization of specificity in a cellular protein interaction network by negative selection
2003 Nature
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
BCL-2 family proteins: changing partners in the dance towards death
2017
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
2012 StandoutNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Hotspot-Centric De Novo Design of Protein Binders
2011 StandoutNobel
De novo design of orthogonal peptide pairs forming parallel coiled‐coil heterodimers
2010
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
Theoretical and Computational Protein Design
2011
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Backrub-Like Backbone Simulation Recapitulates Natural Protein Conformational Variability and Improves Mutant Side-Chain Prediction
2008
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Multistate approaches in computational protein design
2012
Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands
2009
The Design of Coiled-Coil Structures and Assemblies
2005
Computational Design of a PAK1 Binding Protein
2010
Transient Protein-Protein Interactions: Structural, Functional, and Network Properties
2010
Synthetic protein switches: design principles and applications
2014
Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments
2013
An accurate binding interaction model in de novo computational protein design of interactions: If you build it, they will bind
2013
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
Synthetic protein–protein interaction domains created by shuffling Cys 2 His 2 zinc‐fingers
2006
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
ExCage
2014 StandoutNobel
Molecular Determinants of Bim(BH3) Peptide Binding to Pro-Survival Proteins
2012
Detection of Antibodies in Blood Plasma Using Bioluminescent Sensor Proteins and a Smartphone
2016
Solvent-Free Organic Synthesis
2000 StandoutNobel
Single-molecule observation of helix staggering, sliding, and coiled coil misfolding
2012
Emergent Ion-Gated Binding of Cationic Host–Guest Complexes within Cationic M12L24 Molecular Flasks
2014 StandoutNobel
Squaring the Circle in Peptide Assembly: From Fibers to Discrete Nanostructures by de Novo Design
2012
Computational design of water-soluble α-helical barrels
2014 Science
Toward High-Resolution de Novo Structure Prediction for Small Proteins
2005 StandoutScienceNobel
De Novo Design of Four-Helix Bundle Metalloproteins: One Scaffold, Diverse Reactivities
2019
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Stable Carbenes
1999 Standout
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
2016 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer
2011
Protein design: Past, present, and future
2015
A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
2012
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Computational design and experimental verification of a symmetric protein homodimer
2015
COMPUTER-BASED DESIGN OF NOVEL PROTEIN STRUCTURES
2005
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Computational Design of Virus-Like Protein Assemblies on Carbon Nanotube Surfaces
2011 Science
Computational design of a symmetric homodimer using β-strand assembly
2011
De novo design of protein logic gates
2020 StandoutScienceNobel
Highly Anisotropic Stability and Folding Kinetics of a Single Coiled Coil Protein under Mechanical Tension
2011
RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design
2011 StandoutNobel
A Set of de Novo Designed Parallel Heterodimeric Coiled Coils with Quantified Dissociation Constants in the Micromolar to Sub-nanomolar Regime
2013

Works of Amy E. Keating being referenced

Comprehensive Identification of Human bZIP Interactions with Coiled-Coil Arrays
2003 Science
Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL
2010
Design of protein-interaction specificity gives selective bZIP-binding peptides
2009 Nature
Multistate Protein Design Using CLEVER and CLASSY
2013
X‐ray vs. NMR structures as templates for computational protein design
2009
Design of a Heterospecific, Tetrameric, 21-Residue Miniprotein with Mixed α/β Structure
2005
Cluster expansion models for flexible‐backbone protein energetics
2009
Structure-Based Redesign of the Binding Specificity of Anti-Apoptotic Bcl-xL
2012
Designing specific protein–protein interactions using computation, experimental library screening, or integrated methods
2012
Modeling Backbone Flexibility to Achieve Sequence Diversity: The Design of Novel α-Helical Ligands for Bcl-xL
2007
Mcl‐1–Bim complexes accommodate surprising point mutations via minor structural changes
2010
Structural specificity in coiled-coil interactions
2008
Protein binding specificity versus promiscuity
2010
Predicting specificity in bZIP coiled-coil protein interactions
2004
Computing van der Waals energies in the context of the rotamer approximation
2007
SORTCERY—A High–Throughput Method to Affinity Rank Peptide Ligands
2014
Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1
2019
Structure-based Prediction of bZIP Partnering Specificity
2005
Enriching Peptide Libraries for Binding Affinity and Specificity Through Computationally Directed Library Design
2017
Predicting helix orientation for coiled‐coil dimers
2008
SYNZIP Protein Interaction Toolbox: in Vitro and in Vivo Specifications of Heterospecific Coiled-Coil Interaction Domains
2012
Increasing the affinity of selective bZIP‐binding peptides through surface residue redesign
2014
Networks of bZIP Protein-Protein Interactions Diversified Over a Billion Years of Evolution
2013 Science
Gating as a Control Element in Constrictive Binding and Guest Release by Hemicarcerands
1996 Science
Control of Carbene Reactivity by Crystals. A Highly Selective 1,2-H Shift in the Solid-to-Solid Reaction of 1-(4‘-Biphenylyl)-2-phenyldiazopropane to (Z)-1-(4‘-Biphenylyl)-2-phenylpropene
1997
A Set of Computationally Designed Orthogonal Antiparallel Homodimers that Expands the Synthetic Coiled-Coil Toolkit
2014
Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils
2001
Orientation and Oligomerization Specificity of the Bcr Coiled-Coil Oligomerization Domain
2005
Peptide Ligands for Pro-survival Protein Bfl-1 from Computationally Guided Library Screening
2013
Transforming a Nonselective Carbene Rearrangement into a Highly Selective Process by Using Crystalline Media
1996
A Synthetic Coiled-Coil Interactome Provides Heterospecific Modules for Molecular Engineering
2010
Experimental Proof of the Non-Least-Motion Cycloadditions of Dichlorocarbene to Alkenes:  Kinetic Isotope Effects and Quantum Mechanical Transition States
1999
In Silico and in Vitro Elucidation of BH3 Binding Specificity toward Bcl-2
2012
Origins of Stereoselective Carbene 1,2-Shifts and Cycloadditions of 1,2-Dichloroethylidene:  A Theoretical Model Based on CBS-Q and B3LYP Calculations
1997
Rankless by CCL
2026