Citation Impact
Citing Papers
CTLA-4 blockade increases IFNγ-producing CD4 + ICOS hi cells to shift the ratio of effector to regulatory T cells in cancer patients
2008
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help
2003 StandoutScienceNobel
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
2016 StandoutNobel
The ICOS/ICOSL Pathway Is Required for Optimal Antitumor Responses Mediated by Anti–CTLA-4 Therapy
2011
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
PECAM-1 (CD31) Homophilic Interaction Up-Regulates α6β1 on Transmigrated Neutrophils In Vivo and Plays a Functional Role in the Ability of α6 Integrins to Mediate Leukocyte Migration through the Perivascular Basement Membrane
2002
Functionally specialized junctions between endothelial cells of lymphatic vessels
2007 Standout
Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells
2014
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
Increased Frequency of ICOS+ CD4 T Cells as a Pharmacodynamic Biomarker for Anti-CTLA-4 Therapy
2013 StandoutNobel
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
2005 StandoutNature
CD28 Controls Differentiation of Regulatory T Cells from Naive CD4 T Cells
2008
CD43 Regulates Th2 Differentiation and Inflammation
2008
ICOS is critical for T helper cell–mediated lung mucosal inflammatory responses
2001
Expansion and Function of CD8+ T Cells Expressing Ly49 Inhibitory Receptors Specific for MHC Class I Molecules
2004 StandoutNobel
Harnessing the exosome-induced immune response for cancer immunotherapy
2014
The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
2001
New regulatory co-receptors: inducible co-stimulator and PD-1
2002 StandoutNobel
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
2003
Mapping autoimmunity genes
1999
T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
2008
Regulation of endothelial cell contacts during leukocyte extravasation
2002
A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells
2008
Phenotypical and functional specialization of FOXP3+ regulatory T cells
2011
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
2008
Acceleration of the onset of collagen‐induced arthritis by a deficiency of platelet endothelial cell adhesion molecule 1
2003
Membrane vesicles as conveyors of immune responses
2009 Standout
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination
2002
The immunological synapse for B-cell memory: the role of the ICOS and its ligand for the longevity of humoral immunity
2003
Enhanced Susceptibility to Endotoxic Shock and Impaired STAT3 Signaling in CD31-Deficient Mice
2005
Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory
2001
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses
2003
Regulation of immune and autoimmune responses by ICOS
2003
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
2005 Standout
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Regulation of immune responses by extracellular vesicles
2014 Standout
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide
1999
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
B7S1, a Novel B7 Family Member that Negatively Regulates T Cell Activation
2003
Getting to the site of inflammation: the leukocyte adhesion cascade updated
2007 Standout
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
B7-H2 Is a Costimulatory Ligand for CD28 in Human
2011
Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis
2004
PD‐1 ligands expressed on myeloid‐derived APC in the CNS regulate T‐cell responses in EAE
2008
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Mini‐review: Transendothelial migration of leukocytes: through the front door or around the side of the house?
2004
Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
2002
The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T cell function
2001
The B7–CD28 superfamily
2002
Role of ICOS versus CD28 in antiviral immunity
2002
The right place at the right time: novel B7 family members regulate effector T cell responses
2002
B7DC/PDL2 Promotes Tumor Immunity by a PD-1–independent Mechanism
2003
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency
2009
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses
2011
Effector and Memory CTL Differentiation
2006
Different susceptibilities of PECAM-deficient mouse strains to spontaneous idiopathic pneumonitis
2006
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
A Role for Inducible Costimulator Protein in the CD28- Independent Mechanism of Resistance to Toxoplasma gondii
2002
Cutting Edge: Inducible Costimulator Protein Regulates Both Th1 and Th2 Responses to Cutaneous Leishmaniasis
2002
The B7 Family and Cancer Therapy: Costimulation and Coinhibition
2007 StandoutNobel
CD4+CD25+ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion
2004
THE B7 FAMILY REVISITED
2005 Standout
ICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated withHelicobacter pylori
2016 StandoutNobel
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
Inducible Costimulator Protein Controls the Protective T Cell Response Against Listeria monocytogenes
2002
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Constitutive Expression of the B7h Ligand for Inducible Costimulator on Naive B Cells Is Extinguished after Activation by Distinct B Cell Receptor and Interleukin 4 Receptor–mediated Pathways and Can Be Rescued by CD40 Signaling
2002
The Inducible Costimulator Plays the Major Costimulatory Role in Humoral Immune Responses in the Absence of CD28
2004
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
ICOS Controls the Pool Size of Effector-Memory and Regulatory T Cells
2008
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy.
2010 StandoutNobel
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+T cells
2002
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
ICOS Deficiency Is Associated with a Severe Reduction of CXCR5+CD4 Germinal Center Th Cells
2006
Absence of Monocyte Chemoattractant Protein 1 in Mice Leads to Decreased Local Macrophage Recruitment and Antigen-Specific T Helper Cell Type 1 Immune Response in Experimental Autoimmune Encephalomyelitis
2001
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
2001 StandoutNobel
B7h is required for T cell activation, differentiation, and effector function
2003
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities
2016 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Anti-CTLA-4 therapy results in higher CD4 + ICOS hi T cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues
2009
Impaired germinal center formation and recall T-cell–dependent immune responses in mice lacking the costimulatory ligand B7-H2
2003
Cutting Edge: Critical Role of Inducible Costimulator in Germinal Center Reactions
2001
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement
2014
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses
2002
B7-Dc, a New Dendritic Cell Molecule with Potent Costimulatory Properties for T Cells
2001
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
2007 StandoutNobel
Platelet Endothelial Cell Adhesion Molecule Deficiency or Blockade Significantly Reduces Leukocyte Emigration in a Majority of Mouse Strains
2004
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Inducible Costimulatory Molecule-B7-Related Protein 1 Interactions Are Important for the Clonal Expansion and B Cell Helper Functions of Naive, Th1, and Th2 T Cells
2003
Characterization of Mouse and Human B7-H3 Genes
2002
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus
2000
Murine B7-H3 Is a Negative Regulator of T Cells
2004
Works of Amy E. Juedes being referenced
No Significant CTL Cross-Priming by Dendritic Cell-Derived Exosomes during Murine Lymphocytic Choriomeningitis Virus Infection
2009
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice
2002
Kinetics and Cellular Origin of Cytokines in the Central Nervous System: Insight into Mechanisms of Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis
2000
B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization.
1998
Resident and Infiltrating Central Nervous System APCs Regulate the Emergence and Resolution of Experimental Autoimmune Encephalomyelitis
2001
T-bet Controls Autoaggressive CD8 Lymphocyte Responses in Type 1 Diabetes
2004
Antigen-driven effector CD8 T cell function regulated by T-bet
2003
Cutting Edge: B Cell-Deficient Mice Develop Experimental Allergic Encephalomyelitis with Demyelination After Myelin Oligodendrocyte Glycoprotein Sensitization
1998
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice
2002
Selective Retention of Activated CD8+ T Cells by the Normal Liver
1999