Standout Papers
Citation Impact
Citing Papers
Matrix stiffness reverses the effect of actomyosin tension on cell proliferation
2012
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
2012 StandoutNobel
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
2020 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
2013
Talin determines the nanoscale architecture of focal adhesions
2015
Filamin A–β1 Integrin Complex Tunes Epithelial Cell Response to Matrix Tension
2009
Linear viscoelastic behavior of subcutaneous adipose tissue
2008
Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Collagen density promotes mammary tumor initiation and progression
2008
Cell mechanics and the cytoskeleton
2010 StandoutNature
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Mechanical regulation of cell function with geometrically modulated elastomeric substrates
2010
Cell–matrix adhesion
2007
Viscoelastic Retraction of Single Living Stress Fibers and Its Impact on Cell Shape, Cytoskeletal Organization, and Extracellular Matrix Mechanics
2006
The third dimension bridges the gap between cell culture and live tissue
2007 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
2013 Standout
The physics of cancer: the role of physical interactions and mechanical forces in metastasis
2011
Designing materials to direct stem-cell fate
2009 Nature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Hypoxia/reoxygenation: A dynamic regulator of lysyl oxidase‐facilitated breast cancer migration
2007
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Dynamic interplay between the collagen scaffold and tumor evolution
2010
Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens
2012 StandoutNobel
Mechanotransduction gone awry
2008
Forcing form and function: biomechanical regulation of tumor evolution
2010
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
2009 Standout
Cancer Metastasis: Building a Framework
2006 Standout
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
2012
Mechanotransduction and extracellular matrix homeostasis
2014 Standout
Proteoglycans: Master modulators of paracrine fibroblast–carcinoma cell interactions
2009
Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices
2009
Fibroblast Adaptation and Stiffness Matching to Soft Elastic Substrates
2007
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression
2014
Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells
2009
The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis
2013
Mechanotransduction from the ECM to the genome: Are the pieces now in place?
2007
Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis
2007
Collagen-based cell migration models in vitro and in vivo
2009
Conformal piezoelectric systems for clinical and experimental characterization of soft tissue biomechanics
2015
The bladder extracellular matrix. Part I: architecture, development and disease
2009
A focal adhesion protein‐based mechanochemical checkpoint regulates cleft progression during branching morphogenesis
2011
Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
2011
Dynamics and regulation of contractile actin–myosin networks in morphogenesis
2010
Extracellular Matrix Degradation and Remodeling in Development and Disease
2011 Standout
Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
2014
Tensional Homeostasis in Single Fibroblasts
2014
Physical biology of the cancer cell glycocalyx
2018
The extracellular matrix in development and morphogenesis: A dynamic view
2009
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
The rationale for targeting the LOX family in cancer
2012
The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells
2013
Moving from static to dynamic complexity in hydrogel design
2012
Why the stroma matters in breast cancer
2012
Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy
2012
Matrix regulation of idiopathic pulmonary fibrosis: the role of enzymes
2013
Stretchy Proteins on Stretchy Substrates: The Important Elements of Integrin-Mediated Rigidity Sensing
2010
Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth
2011
Biomechanics and biophysics of cancer cells☆
2007
A tense situation: forcing tumour progression
2009 Standout
Exploring the Link Between Human Embryonic Stem Cell Organization and Fate Using Tension-Calibrated Extracellular Matrix Functionalized Polyacrylamide Gels
2012
Integrin Clustering Is Driven by Mechanical Resistance from the Glycocalyx and the Substrate
2009
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2
2011
A survey on deep learning in medical image analysis
2017 Standout
Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia
2008
Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening
2009
Biomechanical regulation of cell orientation and fate
2008
Remodelling the extracellular matrix in development and disease
2014 Standout
Matrices with Compliance Comparable to that of Brain Tissue Select Neuronal over Glial Growth in Mixed Cortical Cultures
2006
Mechanotransduction of keratinocytes in culture and in the epidermis
2007
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
2012
Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression
2010
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Local force and geometry sensing regulate cell functions
2006 Standout
Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells
2009
Stromal induction of breast cancer: Inflammation and invasion
2007
Capturing complex 3D tissue physiology in vitro
2006 Standout
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
2013
Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration
2012
Substrate Modulus Directs Neural Stem Cell Behavior
2008
Three-Dimensional Traction Force Microscopy: A New Tool for Quantifying Cell-Matrix Interactions
2011
Non-Linear Elasticity of Extracellular Matrices Enables Contractile Cells to Communicate Local Position and Orientation
2009
Demystifying the Effects of a Three‐Dimensional Microenvironment in Tissue Morphogenesis
2007
Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage
2009
Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis
2011
Cancer as an evolutionary and ecological process
2006 Standout
Hydrogels with tunable stress relaxation regulate stem cell fate and activity
2015 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Intrinsic extracellular matrix properties regulate stem cell differentiation
2009
Cancer Dissemination—Lessons from Leukocytes
2010
Three-dimensional context regulation of metastasis
2008
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Soft biological materials and their impact on cell function
2006
Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth
2010
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart
2008 Standout
Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension
2010
The hard life of soft cells
2009
Measurement of mechanical tractions exerted by cells in three-dimensional matrices
2010
Mechanotransduction in development: a growing role for contractility
2008
TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration
2020
Long-range mechanical force enables self-assembly of epithelial tubular patterns
2012
α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini
2007
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1
2012
Mechanical control of tissue and organ development
2010
Balancing forces: architectural control of mechanotransduction
2011
Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways
2006
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
The extracellular matrix at a glance
2010 Standout
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Lab-on-Skin: A Review of Flexible and Stretchable Electronics for Wearable Health Monitoring
2017 Standout
Mechanically Activated Integrin Switch Controls α 5 β 1 Function
2009 Science
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Matrix Elasticity, Cytoskeletal Tension, and TGF-β: The Insoluble and Soluble Meet
2008
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Mechanisms of Mechanotransduction
2006
Cellular mechanotransduction: putting all the pieces together again
2006
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis
2016 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Designing Cell-Compatible Hydrogels for Biomedical Applications
2012 StandoutScience
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
2017 StandoutNobel
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
2011 Standout
Paradoxical roles for lysyl oxidases in cancer—A prospect
2007
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Plasticity of cell migration: a multiscale tuning model
2009
In situforce mapping of mammary gland transformation
2011
MECHANOTRANSDUCTION INVOLVING MULTIMODULAR PROTEINS: Converting Force into Biochemical Signals
2006
Breast cancer cell-derived matrix supports vascular morphogenesis
2012
Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer
2006
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues
2009
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
2010
Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry
2014 StandoutNobel
Activation of fibroblasts in cancer stroma
2010
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
2006 Standout
Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness
2012
Works of Amit Gefen being referenced
Are in vivo and in situ brain tissues mechanically similar?
2004
Assessment of mechanical conditions in sub-dermal tissues during sitting: A combined experimental-MRI and finite element approach
2006
Tensional homeostasis and the malignant phenotype
2005 Standout
Age-Dependent Changes in Material Properties of the Brain and Braincase of the Rat
2003
Viscoelastic Properties of Ovine Adipose Tissue Covering the Gluteus Muscles
2007
Automatic detection of cell divisions (mitosis) in live-imaging microscopy images using Convolutional Neural Networks
2015
Mechanics of the normal woman's breast
2007
Mechanical compression-induced pressure sores in rat hindlimb: muscle stiffness, histology, and computational models
2004