Citation Impact
Citing Papers
Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index
2010
Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer
2008 Standout
mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt
2006 Standout
Molecular Classification and Prognostication of Adrenocortical Tumors by Transcriptome Profiling
2009
A Pivotal Role for Heat Shock Protein 90 in Ewing Sarcoma Resistance to Anti-Insulin-like Growth Factor 1 Receptor Treatment: In vitro and In vivo Study
2008
Metastasis: from dissemination to organ-specific colonization
2009 Standout
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Role of insulin-like growth factor 1 receptor signalling in cancer
2005
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
2009 Standout
Insulin-Like Growth Factor 2 in Development and Disease: A Mini-Review
2012
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
2003
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Myeloid-derived suppressor cells coming of age
2018 Standout
Stepping out of the flow: capillary extravasation in cancer metastasis
2007
Dysregulation of growth factor signaling in human hepatocellular carcinoma
2006
IGF-I mediated survival pathways in normal and malignant cells
2006
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
2009 Standout
Contribution of platelets to tumour metastasis
2011 Standout
Synthesis of aryl-heteroaryl ureas (AHUs) based on 4-aminoquinoline and their evaluation against the insulin-like growth factor receptor (IGF-1R)
2010
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
Acromegaly: Re-thinking the cancer risk
2007
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
2009 Standout
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
Cushing's syndrome
2015 Standout
Long‐term effects of calorie or protein restriction on serum IGF‐1 and IGFBP‐3 concentration in humans
2008
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
GSVA: gene set variation analysis for microarray and RNA-Seq data
2013 Standout
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Obesity and cancer: Pathophysiological and biological mechanisms
2008
Tumor-Associated Macrophages: From Mechanisms to Therapy
2014 Standout
Isolation of rare circulating tumour cells in cancer patients by microchip technology
2007 StandoutNature
Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions
2008
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib
2006
The current status of IGF-I assays – A 2009 update
2009
Modulation of response to radiation of human lung cancer cells following insulin-like growth factor 1 receptor inactivation
2004
Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms
2009
Acromegaly: An Endocrine Society Clinical Practice Guideline
2014 Standout
Insulin analogues display IGF‐I‐like mitogenic and anti‐apoptotic activities in cultured cancer cells
2009
Translation of new cancer treatments from pet dogs to humans
2008 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Magnetic nanoparticles in MR imaging and drug delivery
2008 Standout
Remodelling the extracellular matrix in development and disease
2014 Standout
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
2002
Emerging Biological Principles of Metastasis
2017 Standout
Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines
2009
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
2009
Effects of Insulin-like Growth Factor Binding Protein-3 and Farnesyltransferase Inhibitor SCH66336 on Akt Expression and Apoptosis in Non-Small-Cell Lung Cancer Cells
2004
Microenvironmental regulation of metastasis
2008 Standout
PAPP-A and the IGF system
2016
Type IV collagen-initiated signals provide survival and growth cues required for liver metastasis
2011
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
The role of PAPP-A in the IGF system: location, location, location
2015
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance
2009 Standout
IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype
2011
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
2004 Standout
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Involvement of p38α Mitogen-activated Protein Kinase in Lung Metastasis of Tumor Cells
2006
The Host Inflammatory Response Promotes Liver Metastasis by Increasing Tumor Cell Arrest and Extravasation
2007
Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes
2009
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Oral Consumption of Green Tea Polyphenols Inhibits Insulin-Like Growth Factor-I–Induced Signaling in an Autochthonous Mouse Model of Prostate Cancer
2004
In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase
2004
Resistance to age-dependent thymic atrophy in long-lived mice that are deficient in pregnancy-associated plasma protein A
2009
Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies
2010
Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1
2007
The Type 1 Insulin-Like Growth Factor Receptor Pathway
2008
Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
2005 Standout
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
2017
Diabetes and Cancer
2010 Standout
Potential Applications for Circulating Tumor Cells Expressing the Insulin-Like Growth Factor-I Receptor
2007
A randomized controlled trial of octreotide pamoate long-acting release and carboplatin versus carboplatin alone in dogs with naturally occurring osteosarcoma: evaluation of insulin-like growth factor suppression and chemotherapy.
2002
Spermidine in health and disease
2018 StandoutScience
Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement
2013 Standout
Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease
2009
Mechanisms of Diabetic Complications
2013 Standout
The Initial Hours of Metastasis: The Importance of Cooperative Host–Tumor Cell Interactions during Hematogenous Dissemination
2012
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
2012 Standout
Disrupting insulin-like growth factor signaling as a potential cancer therapy
2007
Insulin-like Growth Factor-I–Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells
2008
VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice
2013
The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance
2008
Adrenocortical Carcinoma
2013
Phase I Dose Escalation Study of the Anti–Insulin-Like Growth Factor-I Receptor Monoclonal Antibody CP-751,871 in Patients with Refractory Solid Tumors
2007
Insulin-Like Growth Factor I Controls a Mutually Exclusive Association of RACK1 with Protein Phosphatase 2A and β1 Integrin To Promote Cell Migration
2006
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Signalling pathways of insulin-like growth factors (IGFs) and IGF binding protein-3
2011
Works of Amir Samani being referenced
Characterization of the Host Proinflammatory Response to Tumor Cells during the Initial Stages of Liver Metastasis
2005
The Role of the IGF-I Receptor in the Regulation of Matrix Metalloproteinases, Tumor Invasion and Metastasis
2003
Inhibition of the type I insulin-like growth factor receptor expression and signaling: Novel strategies for antimetastatic therapy
2000
Cooperative Regulation of the Invasive and Metastatic Phenotypes by Different Domains of the Type I Insulin-like Growth Factor Receptor β Subunit
2001
Inhibition of Carcinoma Cell Growth and Metastasis by a Vesicular Stomatitis Virus G-Pseudotyped Retrovector Expressing Type I Insulin-Like Growth Factor Receptor Antisense
2001
The Receptor for the Type I Insulin-like Growth Factor and its Ligands Regulate Multiple Cellular Functions That Impact on Metastasis
2001
Loss of Tumorigenicity and Metastatic Potential in Carcinoma Cells Expressing the Extracellular Domain of the Type 1 Insulin-Like Growth Factor Receptor
2004
The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
2007