Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
2008 StandoutScience
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
2010 StandoutScience
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
2012
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
2015
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
2010
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
I PP2A 1 Affects Tau Phosphorylation via Association with the Catalytic Subunit of Protein Phosphatase 2A
2008
Tau Isoform Composition Influences Rate and Extent of Filament Formation
2012
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
2009
Therapeutic strategies for tau mediated neurodegeneration
2012
Behavioral phenotypes of amyloid‐based genetically modified mouse models of Alzheimer's disease
2005
A decade of modeling Alzheimer's disease in transgenic mice
2006
Synapses and Alzheimer's Disease
2012 StandoutNobel
Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
2005
Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice
2006
Inflammatory processes in Alzheimer's disease
2007
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition
2009
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
2015
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity
2012
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
2007 Standout
Natural oligomers of the amyloid-β protein specifically disrupt cognitive function
2004
Aβ Oligomers – a decade of discovery
2007 Standout
Alzheimer Disease-specific Conformation of Hyperphosphorylated Paired Helical Filament-Tau Is Polyubiquitinated through Lys-48, Lys-11, and Lys-6 Ubiquitin Conjugation
2006
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Intramaze and Extramaze Cue Processing in Adult APPSWE Tg2576 Transgenic Mice.
2004
Autophagic degradation of tau in primary neurons and its enhancement by trehalose
2011
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
2012 Nature
Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease
2005
A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice
2016
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance
2013
Tau phosphorylation and aggregation in Alzheimer's disease pathology
2006
The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
2008
apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
2008
Alpha-synuclein and transgenic mouse models
2004
A Hundred Years of Alzheimer's Disease Research
2006
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
2015
Mechanisms of Protein Seeding in Neurodegenerative Diseases
2012
Reduction of Soluble Aβ and Tau, but Not Soluble Aβ Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles
2006
TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
2007
Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease
2003
Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action
2014
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
2010
Autophagy: Renovation of Cells and Tissues
2011 Standout
Alzheimer's Disease: The Amyloid Cascade Hypothesis
1992 StandoutScience
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
2007 Standout
A Dynamic Relationship between Intracellular and Extracellular Pools of Aβ
2006
Tau in physiology and pathology
2015 Standout
Efficacy of small‐molecule glycogen synthase kinase‐3 inhibitors in the postnatal rat model of tau hyperphosphorylation
2007
Exclusive association and simultaneous appearance of congophilic plaques and AT8-positive dystrophic neurites in Tg2576 mice suggest a mechanism of senile plaque formation and progression of neuritic dystrophy in Alzheimer?s disease
2004
Treatment with an Amyloid-β Antibody Ameliorates Plaque Load, Learning Deficits, and Hippocampal Long-Term Potentiation in a Mouse Model of Alzheimer's Disease
2005
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
2010
Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases
2007
Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
2012
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice
2006
Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements
2007
Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)
2005
Caspase activation precedes and leads to tangles
2010 Nature
Neurovascular regulation in the normal brain and in Alzheimer's disease
2004 Standout
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
2005
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Glial and neuronal control of brain blood flow
2010 StandoutNature
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
2010
Alzheimer's Disease-Like Tau Neuropathology Leads to Memory Deficits and Loss of Functional Synapses in a Novel Mutated Tau Transgenic Mouse without Any Motor Deficits
2006
ADDLs and the signaling web that leads to Alzheimer’s disease
2010
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Probing the Biology of Alzheimer's Disease in Mice
2010
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
2011
Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease
2008
Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death
2006
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
2007
APP Processing and Synaptic Function
2003
β-Amyloid-induced Dynamin 1 Degradation Is Mediated by N-Methyl-D-Aspartate Receptors in Hippocampal Neurons
2006
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
2010
Alzheimer's Disease
2010 Standout
Energy Inhibition Elevates β-Secretase Levels and Activity and Is Potentially Amyloidogenic in APP Transgenic Mice: Possible Early Events in Alzheimer's Disease Pathogenesis
2005
Does my mouse have Alzheimer's disease?
2002
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
2003
Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
2012
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
2006
Accelerated Plaque Accumulation, Associative Learning Deficits, and Up-regulation of α7 Nicotinic Receptor Protein in Transgenic Mice Co-expressing Mutant Human Presenilin 1 and Amyloid Precursor Proteins
2002
Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration
2009
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
2008
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
2012
Fyn Kinase Modulates Synaptotoxicity, But Not Aberrant Sprouting, in Human Amyloid Precursor Protein Transgenic Mice
2004
Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice
2009
Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice
2007
A Decade of Tau Transgenic Animal Models and Beyond
2007
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
2012
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
In VivoMicrodialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
2011
Aβ-Induced Vascular Oxidative Stress and Attenuation of Functional Hyperemia in Mouse Somatosensory Cortex
2004
Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
2014
Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease
2004
A network dysfunction perspective on neurodegenerative diseases
2006 Nature
Increased levels of granular tau oligomers: An early sign of brain aging and Alzheimer's disease
2006
Antibodies against β‐amyloid reduce aβ oligomers, glycogen synthase kinase‐3β activation and τ phosphorylation in vivo and in vitro
2005
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Acute γ-Secretase Inhibition Improves Contextual Fear Conditioning in the Tg2576 Mouse Model of Alzheimer's Disease
2005
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
The molecular pathology of Alzheimer's disease
1991 Standout
A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer’s Disease
2008
Femtomole Immunodetection of Synthetic and Endogenous Amyloid-β Oligomers and Its Application to Alzheimer's Disease Drug Candidate Screening
2003
Aging Analysis Reveals Slowed Tau Turnover and Enhanced Stress Response in a Mouse Model of Tauopathy
2008
Post-translational modifications of tau protein: Implications for Alzheimer's disease
2011
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
The Aging Brain
2008
Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia
2009
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Neuroimmunological Processes in Parkinson’s Disease and their Relation to α-Synuclein: Microglia as the Referee between Neuronal Processes and Peripheral Immunity
2013
Transcriptional neoteny in the human brain
2009 StandoutNobel
Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits
2003
A Century of Alzheimer's Disease
2006 StandoutScience
Immunotherapy Targeting Pathological Tau Protein in Alzheimer's Disease and Related Tauopathies
2008
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection
2010
Mechanisms of memory loss in Aβ and tau mouse models
2005
Self-Assembly of Aβ1-42into Globular Neurotoxins
2003
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity
2007
Alzheimer’s Disease: The Challenge of the Second Century
2011
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
2002
Extracellular Vesicles Containing P301L Mutant Tau Accelerate Pathological Tau Phosphorylation and Oligomer Formation but Do Not Seed Mature Neurofibrillary Tangles in ALZ17 Mice
2016
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
2006
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
2006
Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease
2005
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
2012
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
2007
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
2007
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Converging Pathogenic Mechanisms in Vascular and Neurodegenerative Dementia
2003
Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
2013
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Pathological tau: a loss of normal function or a gain in toxicity?
2005
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Trimeric Tau Is Toxic to Human Neuronal Cells at Low Nanomolar Concentrations
2013
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Ami Mariash being referenced
Motor dysfunction and gliosis with preserved dopaminergic markers in human α-synuclein A30P transgenic mice
2002
Altered short-term hippocampal synaptic plasticity in mutant α-synuclein transgenic mice
2003
Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks
2004
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Spot 14 Gene Deletion Increases Hepatic de Novo Lipogenesis
2001
The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease
2002