Standout Papers
Citation Impact
Citing Papers
Epidermal Growth Factor Receptors with Tyrosine Kinase Domain Mutations Exhibit Reduced Cbl Association, Poor Ubiquitylation, and Down-regulation but Are Efficiently Internalized
2007
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Tracking of Quantum Dot-labeled CFTR Shows Near Immobilization by C-Terminal PDZ Interactions
2006
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Presenilin/γ-secretase-dependent processing of β-amyloid precursor protein regulates EGF receptor expression
2007
Vascular Endothelial Growth Factor Receptor-1 Contributes to Resistance to Anti–Epidermal Growth Factor Receptor Drugs in Human Cancer Cells
2008
Cargo sorting into multivesicular bodies in vitro
2009 StandoutNobel
Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth
2010
Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study
2009
Alzheimer's disease: synapses gone cold
2011
ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration
2008
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis
2012
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
2011 Nature
The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory
2015
Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstituted in Vitro System
2009
ErbB receptors and signaling pathways in cancer
2009
EGFR Antagonists in Cancer Treatment
2008 Standout
Inhibition of Oncogenic Epidermal Growth Factor Receptor Kinase Triggers Release of Exosome-like Extracellular Vesicles and Impacts Their Phosphoprotein and DNA Content
2015
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor
2012
Systems Biology of Growth Factor‐Induced Receptor Endocytosis
2008
Specificity in Signal Transduction
2004
Development of a Method for the Purification and Culture of Rodent Astrocytes
2011
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Derailed endocytosis: an emerging feature of cancer
2008
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Microglial immune checkpoint mechanisms
2018
Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release
2013 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons
2011 StandoutNobel
Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism
2002 Standout
Hyaluronan: from extracellular glue to pericellular cue
2004 Standout
Mechanical coupling maintains the fidelity of NMDA receptor–mediated currents
2014
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
The Role of Ionotropic Glutamate Receptors in Childhood Neurodevelopmental Disorders: Autism Spectrum Disorders and Fragile X Syndrome
2014
Direct lineage conversions: unnatural but useful?
2011
Gating Modes in AMPA Receptors
2010
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
ErbBs in lung cancer
2008
ESCRTing proteins in the endocytic pathway
2007
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Signaling from endosomes: Location makes a difference
2008
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Regulation of neural progenitor cell development in the nervous system
2008
Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons
2011
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation
2013 StandoutNobel
Cellular Reprogramming: Recent Advances in Modeling Neurological Diseases
2011
Mechanisms of Modal Activation of GluA3 Receptors
2011
Quantitative modeling perspectives on the ErbB system of cell regulatory processes
2008
Therapies Directed Against Epidermal Growth Factor Receptor in Aerodigestive Carcinomas
2007
Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions
2011
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Endocytosis and intracellular trafficking of ErbBs
2008
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics
2017
An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors
2003
Efficient induction of functional neurons from adult human fibroblasts
2011
Small molecules enable highly efficient neuronal conversion of human fibroblasts
2012
Accelerating progress in induced pluripotent stem cell research for neurological diseases
2012
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes
2014
Modeling psychiatric disorders at the cellular and network levels
2012
The ESCRT Pathway
2011
Sprouty proteins, masterminds of receptor tyrosine kinase signaling
2008
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Induced Neuronal Cells: How to Make and Define a Neuron
2011 StandoutNobel
The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond
2007
The insulin and EGF receptor structures: new insights into ligand-induced receptor activation
2007
Synaptic AMPA receptor composition in development, plasticity and disease
2016
EGFR endocytosis requires its kinase activity and N-terminal transmembrane dimerization motif
2013
Molecular Roadblocks for Cellular Reprogramming
2012
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Mechanisms for oncogenic activation of the epidermal growth factor receptor
2007
Historical Origins of Transdifferentiation and Reprogramming
2011
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
The role of EGF ‐EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment
2013
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Clues from cell metabolism
2010 StandoutNatureNobel
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
Mussel-Inspired Surface Chemistry for Multifunctional Coatings
2007 StandoutScience
Molecular basis for multimerization in the activation of the epidermal growth factor receptor
2016
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Regulating the dynamics of EGF receptor signaling in space and time
2005
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Roles for Growth Factors in Cancer Progression
2010
Neurotransmitter release regulated by a MALS–liprin-α presynaptic complex
2005
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
A Eukaryotic Specific Transmembrane Segment is Required for Tetramerization in AMPA Receptors
2013
AMPA receptors as a molecular target in epilepsy therapy
2013
Human in vitro models for understanding mechanisms of autism spectrum disorder
2020
Works of Ami Citri being referenced
Hsp90 restrains ErbB‐2/HER2 signalling by limiting heterodimer formation
2004
The deaf and the dumb: the biology of ErbB-2 and ErbB-3
2003
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy
2002
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
2017
Hsp90 Recognizes a Common Surface on Client Kinases
2006
Polar Expression of ErbB-2/HER2 in Epithelia
2003
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity
2004
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding
2004
Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling
2007
EGF–ERBB signalling: towards the systems level
2006 Standout
A module of negative feedback regulators defines growth factor signaling
2007
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
2004
Suppressors of Cytokine Signaling 4 and 5 Regulate Epidermal Growth Factor Receptor Signaling
2004
Calcium Binding to PICK1 Is Essential for the Intracellular Retention of AMPA Receptors Underlying Long-Term Depression
2010
Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms
2007 Standout
Comprehensive qPCR profiling of gene expression in single neuronal cells
2011 StandoutNobel
The Achilles Heel of ErbB-2/HER2: Regulation by the Hsp90 Chaperone Machine and Potential for Pharmacological Intervention
2004