Amber Wolfe

Oxidative stress and autophagy: the clash between damage and metabolic needs

AMPK: guardian of metabolism and mitochondrial homeostasis

Nrf2-Keap1 signaling in oxidative and reductive stress

ROS in cancer therapy: the bright side of the moon

ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development

Hepatocellular carcinoma

mTOR at the nexus of nutrition, growth, ageing and disease

Biological Functions of Autophagy Genes: A Disease Perspective

Mechanisms of NAFLD development and therapeutic strategies

mTOR Signaling in Growth, Metabolism, and Disease

Neutrophil extracellular traps in immunity and disease

The Role of Tumor Suppressor p53 in the Antioxidant Defense and Metabolism

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1

Oxidative Stress in Cancer

Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

NF-κB, inflammation, immunity and cancer: coming of age

Inflammation in obesity, diabetes, and related disorders

The integrated stress response

Retrograde signaling from autophagy modulates stress responses

AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3