Citation Impact
Citing Papers
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Fuzziness: linking regulation to protein dynamics
2011
Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering
2011
Pyroptosis versus necroptosis: similarities, differences, and crosstalk
2018
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size
2013
The unfoldomics decade: an update on intrinsically disordered proteins
2008
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
2015 StandoutNobel
Engineering synthetic biomolecular condensates
2023
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Controlling entropy to tune the functions of intrinsically disordered regions
2014
Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes
2010
RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia
2007
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
Rethinking amide bond synthesis
2011 StandoutNature
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator
2012
Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrPSc Glycoform and Prion Infectivity
2014
Hallmarks of aging: An expanding universe
2023 Standout
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins
2013
The machinery of macroautophagy
2013 Standout
Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis
2018
Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design
2017
Regulated unfolding of proteins in signaling
2013
BCL-2 family proteins: changing partners in the dance towards death
2017
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
2016
Conformational Control of Energy Transfer: A Mechanism for Biocompatible Nanocrystal‐Based Sensors
2012 StandoutNobel
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
2021
Biophysical characterization of intrinsically disordered proteins
2009
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The cullin protein family
2011
BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
2019
Decoding ALS: from genes to mechanism
2016 StandoutNature
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction
2007
Pre-folding IκBα Alters Control of NF-κB Signaling
2008
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
The rules of disorder or why disorder rules
2009
Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7
2012 StandoutNobel
An interconnected hierarchical model of cell death regulation by the BCL-2 family
2015
Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif
2010
Molecular mimicry of SUMO promotes DNA repair
2009
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Autophagy in Human Health and Disease
2013 Standout
Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments
2013
Linking folding and binding
2009
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
2018
Intrinsic disorder in cell signaling and gene transcription
2011
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21
2011
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Small-molecule allosteric inhibitors of BAX
2019
Mitochondria as multifaceted regulators of cell death
2019 Standout
Prediction of Protein Binding Regions in Disordered Proteins
2009
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
2015
Ubc9 Sumoylation Regulates SUMO Target Discrimination
2008
Cellular Strategies for Regulating Functional and Nonfunctional Protein Aggregation
2012
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Cancer-related inflammation
2008 StandoutNature
Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
2016
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
BIM-Mediated Membrane Insertion of the BAK Pore Domain Is an Essential Requirement for Apoptosis
2013
From Sequence and Forces to Structure, Function, and Evolution of Intrinsically Disordered Proteins
2013
Exploring the Sequence-based Prediction of Folding Initiation Sites in Proteins
2017
Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance
2016
Autophagy and human diseases
2013
Assessing protein disorder and induced folding
2005
Dynamic protein–DNA recognition: beyond what can be seen
2011
Close encounters of the third kind: disordered domains and the interactions of proteins
2009
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Structure, Dynamics, Assembly, and Evolution of Protein Complexes
2014
Sending Signals Dynamically
2009 Science
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Sequence–Structure–Binding Relationships Reveal Adhesion Behavior of the Car9 Solid-Binding Peptide: An Integrated Experimental and Simulation Study
2020 StandoutNobel
Introducing Protein Intrinsic Disorder
2014
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Cytokine Storm
2020 Standout
Application of a Proteolysis/Mass Spectrometry Method for Investigating the Effects of Inhibitors on Hydroxylase Structure
2009
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Delivery and Subcellular Targeting of Dendrimer-Based Fluorescent pH Sensors in Living Cells
2010
Cis−Trans Isomerization of Organic Molecules and Biomolecules: Implications and Applications
2003
Engineering Biomolecular Self‐Assembly at Solid–Liquid Interfaces
2020 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Regulation of Cell Division by Intrinsically Unstructured Proteins: Intrinsic Flexibility, Modularity, and Signaling Conduits
2008
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation
2015 StandoutNobel
Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
2019
A hypothalamic pathway for Augmentor α–controlled body weight regulation
2022
Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes
2014
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Differential retrotranslocation of mitochondrial Bax and Bak
2014
De novo design of protein logic gates
2020 StandoutScienceNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Redox Control of the Binding Modes of an Organic Receptor
2015 StandoutNobel
Isolation, Sequencing, and Structure−Activity Relationships of Cyclotides
2010
Works of Amanda Nourse being referenced
Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
2016
Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation
2018
Heterodimerization of the Sialidase NEU1 with the Chaperone Protective Protein/Cathepsin A Prevents Its Premature Oligomerization
2009
Mechanism for the activation of the anaplastic lymphoma kinase receptor
2021 Nature
A Comparison of the Self-association Behavior of the Plant Cyclotides Kalata B1 and Kalata B2 via Analytical Ultracentrifugation
2003
Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis
2016
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
2009
BID-induced structural changes in BAK promote apoptosis
2013
Physicochemical characterization of generation 5 polyamidoamine dendrimers
2000
Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway
2011
Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown
2013
Molecular Basis for the Specificity of p27 Toward Cyclin-dependent Kinases that Regulate Cell Division
2005
Intrinsically Unstructured Domains of Arf and Hdm2 Form Bimolecular Oligomeric Structures In Vitro and In Vivo
2008
Role of Intrinsic Flexibility in Signal Transduction Mediated by the Cell Cycle Regulator, p27Kip1
2008
Structure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO Pathway
2007
Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
2016
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis
2013
The Cytoplasmic Domain of the T-Cell Receptor zeta Subunit Does Not Form Disordered Dimers
2013
Structural polymorphism in the N-terminal oligomerization domain of NPM1
2014
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
2018