Citation Impact
Citing Papers
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
2010
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
2009 Standout
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
2010
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory
2010 Science
The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response
2013
Systematic Comparison of Gene Expression between Murine Memory and Naive B Cells Demonstrates That Memory B Cells Have Unique Signaling Capabilities
2008
Rho family GTPases and their regulators in lymphocytes
2009
Transcriptional regulation of memory B cell differentiation
2020
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
B cell memory: building two walls of protection against pathogens
2019
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Complement receptors CD21 and CD35 in humoral immunity
2007
Plasma cell differentiation and survival
2008
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Rac1 and Rac2 GTPases in haematopoiesis
2004
Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5
2004
Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling
2010
Autoinflammatory Disease Reloaded: A Clinical Perspective
2010 Standout
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Molecular programming of B cell memory
2011
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
The Many Roles of FAS Receptor Signaling in the Immune System
2009
Germinal Center and Extrafollicular B Cell Responses in Vaccination, Immunity, and Autoimmunity
2020
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Mcl-1 is essential for the survival of plasma cells
2013
Cytokine-secreting follicular T cells shape the antibody repertoire
2009
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
T Follicular Helper Cell Differentiation, Function, and Roles in Disease
2014
Pattern Recognition Receptors and Inflammation
2010 Standout
CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells
2009
ATP-sensitive potassium channels mediate survival during infection in mammals and insects
2007 StandoutNobel
Germinal-Center Organization and Cellular Dynamics
2007
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
2010
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
The genetics and immunopathogenesis of inflammatory bowel disease
2008
Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter
2010
Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers
2022
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
2011
Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites
2015
TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity
2018
T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite
2016
Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children
2015
Assessment of telomere length and factors that contribute to its stability
2003
Disruption of IL-21 Signaling Affects T Cell-B Cell Interactions and Abrogates Protective Humoral Immunity to Malaria
2015
T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses
2015
SOCS3 Is a Critical Physiological Negative Regulator of G-CSF Signaling and Emergency Granulopoiesis
2004
Systemic Lupus Erythematosus
2011 Standout
Regulation of Class-Switch Recombination and Plasma Cell Differentiation by Phosphatidylinositol 3-Kinase Signaling
2006
Fas Is Required for Clonal Selection in Germinal Centers and the Subsequent Establishment of the Memory B Cell Repertoire
2001
Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4
2014 StandoutNobel
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses
2003
Regulation of memory B and plasma cell differentiation
2017
Dysregulation of germinal centres in autoimmune disease
2009
Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease
2016
Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development
2010
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
2020 Standout
PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
2010
PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors
2018
The Transcriptional Regulation of Germinal Center Formation
2018
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
2007
The Transcriptional Regulation of B Cell Lineage Commitment
2007
Structurally Distinct Phosphatases CD45 and CD148 Both Regulate B Cell and Macrophage Immunoreceptor Signaling
2008
Interleukin (IL)-21 promotes intestinal IgA response to microbiota
2015
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
2013 Standout
Plasma cell development and survival
2010
Lymphoid organ development and cell migration
2003
Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
2006
Germinal centres: role in B-cell physiology and malignancy
2007
The PI3K Pathway in Human Disease
2017 Standout
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2
2017
B Cell Responses: Cell Interaction Dynamics and Decisions
2019
Germinal center B and follicular helper T cells: siblings, cousins or just good friends?
2011
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
Rho GTPases and Regulation of Hematopoietic Stem Cell Localization
2008
CD95's deadly mission in the immune system
2000 Nature
Essential role for autophagy in the maintenance of immunological memory against influenza infection
2014
Terminal differentiation of lymphocytes depends on Blimp-1
2007
Initiation of Plasma-Cell Differentiation Is Independent of the Transcription Factor Blimp-1
2007
Notch2 Is Preferentially Expressed in Mature B Cells and Indispensable for Marginal Zone B Lineage Development
2003
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Foxo‐mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3‐only protein
2013
CD80 Expression on B Cells Regulates Murine T Follicular Helper Development, Germinal Center B Cell Survival, and Plasma Cell Generation
2012
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
Recent Advances in the Genetics of Autoimmune Disease
2008
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Plasticity and Heterogeneity in the Generation of Memory B Cells and Long-Lived Plasma Cells: The Influence of Germinal Center Interactions and Dynamics
2010
Bcl6 and Maf Cooperate To Instruct Human Follicular Helper CD4 T Cell Differentiation
2012
Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease
2013
In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development
2010
Tertiary lymphoid structures, drivers of the anti‐tumor responses in human cancers
2016
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Follicular Helper CD4 T Cells (TFH)
2011 Standout
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset
2011 StandoutNobel
Proinflammatory T helper type 17 cells are effective B-cell helpers
2010
Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help
2017
The origins, function, and regulation of T follicular helper cells
2012
T follicular regulatory cells
2016
Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells
2017
Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction
2010
Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases
2003 Science
Rac2-Deficient Hematopoietic Stem Cells Show Defective Interaction with the Hematopoietic Microenvironment and Long-Term Engraftment Failure
2005
Germinal Centers
2012
Chimeric Antigen Receptor Therapy
2018 Standout
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Regulation and Functions of Blimp-1 in T and B Lymphocytes
2008
Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells
2014
Follicular Helper T Cells
2016
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling
2003 Science
Phosphoinositide 3-Kinase : Diverse Roles in Immune Cell Activation
2004
Zinc finger–IRF composite elements bound by Ikaros/IRF4 complexes function as gene repression in plasma cell
2018
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses
2010
Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory
2012
Therapeutic Effects of a TANK ‐Binding Kinase 1 Inhibitor in Germinal Center–Driven Collagen‐Induced Arthritis
2018
Helper T‐cell identity and evolution of differential transcriptomes and epigenomes
2013
Recruitment and Retention of B Cells in the Central Nervous System in Response to Alphavirus Encephalomyelitis
2012
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood
2016
Compact Biocompatible Quantum Dots Functionalized for Cellular Imaging
2008 StandoutNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Follicular helper T cells mediate IgE antibody response to airborne allergens
2016
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
A germinal center–independent pathway generates unswitched memory B cells early in the primary response
2012
Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)
2010
Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits
2014
Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers
2014
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
2011
Works of Amanda Light being referenced
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism
2010
CTLA4Ig Alters the Course of Autoimmune Disease Development in Lyn−/− Mice
2009
Affinity Maturation of the Primary Response by V Gene Diversification
1998
Single cell sorting and cloning
2000
CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers
2005
Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB
2017
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
2012
BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
2010
bcl-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells
2000
The development of functional B lymphocytes in conditional PU.1 knock-out mice
2005
Architectural Defects in the Spleens of Nkx2-3-Deficient Mice Are Intrinsic and Associated with Defects in Both B Cell Maturation and T Cell-Dependent Immune Responses
2003
The Rac2 Guanosine Triphosphatase Regulates B Lymphocyte Antigen Receptor Responses and Chemotaxis and Is Required for Establishment of B-1a and Marginal Zone B Lymphocytes
2002
The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation
2014
Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell–Intrinsic Mechanism
2014
Early appearance of germinal center–derived memory B cells and plasma cells in blood after primary immunization
2005
Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells
2007