Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Structure of a Synaptic γδ Resolvase Tetramer Covalently Linked to Two Cleaved DNAs
2005 StandoutScienceNobel
Active Site Tightness and Substrate Fit in DNA Replication
2002
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
2003
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
2010 StandoutScienceNobel
Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex
2009 StandoutNobel
Magnesium-cationic Dummy Atom Molecules Enhance Representation of DNA Polymerase β in Molecular Dynamics Simulations: Improved Accuracy in Studies of Structural Features and Mutational Effects
2006 StandoutNobel
2.3 Å crystal structure of the catalytic domain of DNA polymerase β
1994
Specific Interaction of DNA Polymerase β and DNA Ligase I in a Multiprotein Base Excision Repair Complex from Bovine Testis
1996
Evidence for an Imino Intermediate in the DNA Polymerase β Deoxyribose Phosphate Excision Reaction
1996
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation
1998
Use of organic cosmotropic solutes to crystallize flexible proteins: application to T7 RNA polymerase and its complex with the inhibitor T7 lysozyme
1997 StandoutNobel
Crystal Structures of the Bacillus stearothermophilus CCA-Adding Enzyme and Its Complexes with ATP or CTP
2002 StandoutNobel
Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP
2000
Magnesium-Induced Assembly of a Complete DNA Polymerase Catalytic Complex
2006
An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein
2000
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Computer simulation studies of the fidelity of DNA polymerases
2003 StandoutNobel
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Structural basis for template-independent RNA polymerization
2004 Nature
Gel Shift and UV Cross-linking Analysis of Tetrahymena Telomerase
1995 StandoutNobel
Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity
2006
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
Replication of non-hydrogen bonded bases by DNA polymerases: A mechanism for steric matching
1998
Mammalian base excision repair and DNA polymerase beta
1998
Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate Peptides
2003
Yeast RNA Polymerase II at 5 Å Resolution
1999 StandoutNobel
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal
1998 Nature
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair
1997
SURVEY AND SUMMARY: The morph server: a standardized system for analyzing and visualizing macromolecular motions in a database framework
2000
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
1998 Nature
Human DNA Polymerase β Recognizes Single-stranded DNA Using Two Different Binding Modes
1998
The helix-hairpin-helix DNA-binding motif: a structural basis for non- sequence-specific recognition of DNA
1996
A single tyrosine prevents insertion of ribonucleotides in the eukaryotic-type φ29 DNA polymerase 1 1Edited by A. R. Fersht
1999
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
A Thumb Subdomain Mutant of the Large Fragment of Escherichia coli DNA Polymerase I with Reduced DNA Binding Affinity, Processivity, and Frameshift Fidelity
1996
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes
2003 StandoutNobel
An equivalent metal ion in one- and two-metal-ion catalysis
2008
Two conformations of RNA polymerase II revealed by electron crystallography
1997 StandoutNobel
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes
1998 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway
1997
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B‐family polymerases
2007 StandoutNobel
DNA Structure and Aspartate 276 Influence Nucleotide Binding to Human DNA Polymerase β
2001
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase
1995
Efficient replication between non-hydrogen-bonded nucleoside shape analogs
1998
Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme
1998 StandoutNobel
Role of the first aspartate residue of the “YxDTDS” motif of ø29 DNA polymerase as a metal ligand during both TP-primed and DNA-primed DNA synthesis
1998
ø29 DNA polymerase residue Lys383, invariant at motif B of DNA-dependent polymerases, is involved in dNTP binding 1 1Edited by A. R. Fesht
1997
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage φ29
2004 StandoutNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Identification of the Acidic Residues in the Active Site of DNA Polymerase III
1999
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates
1998 StandoutNobel
The Fidelity of DNA Polymerase β during Distributive and Processive DNA Synthesis
1999
Structure and mechanism of DNA polymerases
2005
Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates
1995
Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
2002
An open and closed case for all polymerases
1999
A model for the mechanism of polymerase translocation 1 1Edited by A. R. Fersht
1997
Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III
2006
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Highly Organized but Pliant Active Site of DNA Polymerase β: Compensatory Mechanisms in Mutant Enzymes Revealed by Dynamics Simulations and Energy Analyses
2004
Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure
2003
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Fractions to Functions: RNA Polymerase II Thirty Years Later
1998
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
Structural insights into DNA polymerase β fidelity: hold tight if you want it right
1998
Crystal Structure of the Human CCA-adding Enzyme: Insights into Template-independent Polymerization
2003 Nobel
A positively charged residue of phi29 DNA polymerase, highly conserved in DNA polymerases from families A and B, is involved in binding the incoming nucleotide
2002
DNA Polymerases: Structural Diversity and Common Mechanisms
1999 StandoutNobel
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
2012 Nature
Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit
2008 StandoutNobel
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
Crystal structure of a pol α family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp . 9°N-7 1 1Edited by D. Rees
2000
Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template
2004 StandoutNatureNobel
[11] Purification and domain-mapping of mammalian DNA polymerase β
1995
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Minor Groove Interactions between Polymerase and DNA: More Essential to Replication than Watson−Crick Hydrogen Bonds?
1999
The CCA-adding Enzyme Has a Single Active Site
1998
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius
1999 Nobel
Spectroscopic studies of the structural domains of mammalian DNA beta-polymerase.
1991
Choosing the right sugar: How polymerases select a nucleotide substrate
1997
Initiation of viral RNA-dependent RNA polymerization
2004
Structure of Yeast Poly(A) Polymerase Alone and in Complex with 3'-dATP
2000 Science
Characterization of Proton-Transfer Catalysis by Serum Albumins
2000
Energetics and Dynamics of Enzymatic Reactions
2001 StandoutNobel
Polymerase structures and function: variations on a theme?
1995 StandoutNobel
The mechanism of action of T7 DNA polymerase
1998
An Integrated Model of the Transcription Complex in Elongation, Termination, and Editing
1998 Science
Quality Control by DNA Repair
1999 StandoutScienceNobel
Theoretical Investigation of the Binding Free Energies and Key Substrate-Recognition Components of the Replication Fidelity of Human DNA Polymerase β
2002 StandoutNobel
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
1995
Localization of the active site of the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme
1997
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides
1998
Quantum Chemical Investigation of Enzymatic Activity in DNA Polymerase β. A Mechanistic Study
2000
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Conferring RNA polymerase Activity to a DNA polymerase: A single residue in reverse transcriptase controls substrate selection
1997
Structure and Mechanism of DNA Polymerase β
2006
Getting a grip on how DNA polymerases function.
2001
A Reexamination of the Nucleotide Incorporation Fidelity of DNA Polymerases
2002
Accuracy, lesion bypass, strand displacement and translocation by DNA polymerases
2004 StandoutNobel
Ribonuclease A
1998
A Field Guide to Foldamers
2001 Standout
Excision of Deoxyribose Phosphate Residues by DNA Polymerase β During DNA Repair
1995 Science
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerases.
1996
Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase
2002
Elucidating the Nature of Enzyme Catalysis Utilizing a New Twist on an Old Methodology: Quantum Mechanical−Free Energy Calculations on Chemical Reactions in Enzymes and in Aqueous Solution
2000
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
Free-Energy Perturbation Calculations of DNA Destabilization by Base Substitutions: The Effect of Neutral Guanine·Thymine, Adenine·Cytosine and Adenine·Difluorotoluene Mismatches
2000 StandoutNobel
DNA glycosylases in the base excision repair of DNA
1997
Mapping the Protein Universe
1996 Science
Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases.
1996
Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase β's closing
2004
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases
1994 Science
Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns.
1995
Two-Metal-Ion Catalysis in Adenylyl Cyclase
1999 ScienceNobel
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes
2000
Simulating the Effect of DNA Polymerase Mutations on Transition-State Energetics and Fidelity: Evaluating Amino Acid Group Contribution and Allosteric Coupling for Ionized Residues in Human Pol β
2006 StandoutNobel
Works of Amalendra Kumar being referenced
The Domains of Mammalian Base Excision Repair Enzyme N-Methylpurine-DNA Glycosylase
1996
Molecular Cloning and High-Level Expression of Human Polymerase β cDNA and Comparison of the Purified Recombinant Human and Rat Enzymes
2000
Characterization of the Tryptophan Fluorescence and Hydrodynamic Properties of Rat DNA Polymerase β
1994
Identification and properties of the catalytic domain of mammalian DNA polymerase .beta.
1990
Mammalian DNA polymerase .beta.: Characterization of a 16-kDa transdomain fragment containing the nucleic acid-binding activities of the native enzyme
1992
dNTP Binding Site in Rat DNA Polymerase β Revealed by Controlled Proteolysis and Azido Photoprobe Cross-Linking
1996
DNA Polymerase β and DNA Synthesis in Xenopus Oocytes and in a Nuclear Extract
1992 Science
STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP
1994
Crystal Structure of Rat DNA Polymerase β: Evidence for a Common Polymerase Mechanism
1994 Science
Identification ofNG-Methylarginine Residues in Human Heterogeneous RNP Protein A1: Phe/Gly-Gly-Gly-Arg-Gly-Gly-Gly/Phe Is a Preferred Recognition Motif
1997
Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP
1994 Science
Identification of residues in the single-stranded DNA-binding site of the 8-kDa domain of rat DNA polymerase beta by UV cross-linking.
1993