Citation Impact
Citing Papers
Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct Mechanisms
2001 Science
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
2001 StandoutScience
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
Fork Reversal and ssDNA Accumulation at Stalled Replication Forks Owing to Checkpoint Defects
2002 Science
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response
2000
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
1999
Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks
2009
EXO1 Plays a Role in Generating Type I and Type II Survivors in Budding Yeast
2004
Chromatin Modifications and Their Function
2007 Standout
Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere
2001
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
2004 Nature
Cell-cycle checkpoints and cancer
2004 StandoutNature
Regulation of Telomere Elongation by the Cyclin-Dependent Kinase CDK1
2006 StandoutNobel
Replication Protein A phosphorylation and the cellular response to DNA damage
2004
Arrest, Adaptation, and Recovery following a Chromosome Double-strand Break in Saccharomyces cerevisiae
2000
P53 and radiation responses
2003
Reconstitution of an ATM-Dependent Checkpoint that Inhibits Chromosomal DNA Replication following DNA Damage
2000
Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint
2003
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Relocalization of Telomeric Ku and SIR Proteins in Response to DNA Strand Breaks in Yeast
1999
Lcd1p Recruits Mec1p to DNA Lesions In Vitro and In Vivo
2002
Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae
2000
Structural Insights into Yeast Telomerase Recruitment to Telomeres
2017
ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism
2003
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Recovery from Checkpoint-Mediated Arrest after Repair of a Double-Strand Break Requires Srs2 Helicase
2002
Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases α and δ
1999
ATR: an essential regulator of genome integrity
2008
Recruitment of the INO80 Complex by H2A Phosphorylation Links ATP-Dependent Chromatin Remodeling with DNA Double-Strand Break Repair
2004
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
All Things Must End: Telomere Dynamics in Yeast
2000
The Mre11 complex and ATM: collaborating to navigate S phase
2000
Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
2000
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
2001
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae
2001 Nature
Repair of Strand Breaks by Homologous Recombination
2013
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
DNA structure dependent checkpoints as regulators of DNA repair
2002
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin
2002 StandoutNobel
DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2
2002
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
EXO1 -dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70 Δ mutants
2002
Differential Suppression of DNA Repair Deficiencies of Yeast rad50, mre11 and xrs2 Mutants by EXO1 and TLC1 (the RNA Component of Telomerase)
2002
MEC1-Dependent Redistribution of the Sir3 Silencing Protein from Telomeres to DNA Double-Strand Breaks
1999
Partners and pathways
2000
Choreography of the DNA Damage Response
2004
Nuclear pore complexes in the organization of silent telomeric chromatin
2000 Nature
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
Sensing and responding to DNA damage
2000
The Dynamics of Homologous Pairing during Mating Type Interconversion in Budding Yeast
2006
Regulation of Saccharomyces Rad53 Checkpoint Kinase during Adaptation from DNA Damage–Induced G2/M Arrest
2001
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
2008 Nature
DNA double-strand breaks: signaling, repair and the cancer connection
2001 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
2000 StandoutNature
Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenance
2002
The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation
2006
RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site
2001
Switching and Signaling at the Telomere
2001 StandoutNobel
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
2001
DNA ends: maintenance of chromosome termini versus repair of double strand breaks
2000
Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends
2008
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
An ATR- and Cdc7-Dependent DNA Damage Checkpoint that Inhibits Initiation of DNA Replication
2003
Non-transcriptional control of DNA replication by c-Myc
2007 Nature
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
The yeast Xrs2 complex functions in S phase checkpoint regulation
2001
The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling
2002
Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break
2004
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
2006
DNA damage response at functional and dysfunctional telomeres
2008
The Many Interfaces of Mre11
1998
DNA recombination: the replication connection
1999
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
2001 Nature
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Multiple roles of ATM in monitoring and maintaining DNA integrity
2010
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
2008
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
DNA Repair Protein Rad55 Is a Terminal Substrate of the DNA Damage Checkpoints
2000
Involvement of Replicative Polymerases, Tel1p, Mec1p, Cdc13p, and the Ku Complex in Telomere-Telomere Recombination
2002
Two Survivor Pathways That Allow Growth in the Absence of Telomerase Are Generated by Distinct Telomere Recombination Events
2001 StandoutNobel
Haploinsufficiency of mTR results in defects in telomere elongation
2002 StandoutNobel
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein.
2000
Break-Induced Replication and Recombinational Telomere Elongation in Yeast
2006
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Exo1 Roles for Repair of DNA Double-Strand Breaks and Meiotic Crossing Over inSaccharomyces cerevisiae
2000
Replication protein A-mediated recruitment and activation of Rad17 complexes
2003
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Break-induced replication: A review and an example in budding yeast
2001
Ku is associated with the telomere in mammals
1999 StandoutNobel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
The Mre11 Nuclease Is Not Required for 5′ to 3′ Resection at Multiple HO-Induced Double-Strand Breaks
2004
Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
2007
Function of a Conserved Checkpoint Recruitment Domain in ATRIP Proteins
2007
Rfc4 Interacts with Rpa1 and Is Required for Both DNA Replication and DNA Damage Checkpoints in Saccharomyces cerevisiae
2001
Genetic Steps of Mammalian Homologous Repair with Distinct Mutagenic Consequences
2004
DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex
2001
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
EXO1 Plays a Role in Generating Type I and Type II Survivors in Budding Yeast
2004
The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling
2008
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 protein
2000
DNA Length Dependence of the Single-Strand Annealing Pathway and the Role of Saccharomyces cerevisiae RAD59 in Double-Strand Break Repair
2000
Exo1 and Rad24 Differentially Regulate Generation of ssDNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants
2004
Cancer Genome Landscapes
2013 StandoutScience
Surviving the Breakup: The DNA Damage Checkpoint
2006
Short Telomeres Induce a DNA Damage Response inSaccharomyces cerevisiae
2003 StandoutNobel
Cdc13 Telomere Capping Decreases Mec1 Association but Does Not Affect Tel1 Association with DNA Ends
2007
Links between replication and recombination in Saccharomyces cerevisiae : A hypersensitive requirement for homologous recombination in the absence of Rad27 activity
2001
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
Interfaces Between the Detection, Signaling, and Repair of DNA Damage
2002 Science
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Recruitment of the Type B Histone Acetyltransferase Hat1p to Chromatin Is Linked to DNA Double-Strand Breaks
2006
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
Reconstitution of Human DNA Polymerase δ Using Recombinant Baculoviruses
2002
End Resection Initiates Genomic Instability in the Absence of Telomerase
2003 StandoutNobel
Telomere Dysfunction Triggers Developmentally Regulated Germ Cell Apoptosis
2001 StandoutNobel
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
2004 StandoutNobel
Works of Allyson Holmes being referenced
Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage
1998
Double-Strand Break Repair in Yeast Requires Both Leading and Lagging Strand DNA Polymerases
1999
Physical Monitoring of HO-Induced Homologous Recombination
2003
Role of DNA Replication Proteins in Double-Strand Break-Induced Recombination in Saccharomyces cerevisiae
2004