Citation Impact
Citing Papers
Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers
2003
Catalytic organometallic anticancer complexes
2008
Teratoma Formation by Human Embryonic Stem Cells Is Site Dependent and Enhanced by the Presence of Matrigel
2008
Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design
2015
Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence
2007 Standout
Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity
2014
American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
2007 Standout
Relevance of Breast Cancer Cell Lines as Models for Breast Tumours: An Update
2004
CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: identification of an endocrine-sensitive subgroup.
2002
Kinetics of Aquation and Anation of Ruthenium(II ) Arene Anticancer Complexes, Acidity and X‐ray Structures of Aqua Adducts
2003
The path for metal complexes to a DNA target
2013
BRCA1 and BRCA2: 1994 and beyond
2004
Targeting hypoxia in cancer therapy
2011 Standout
Estrogen receptors and human disease
2006 Standout
Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene anticancer complexes
2012
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
2008 Standout
Issues and progress with protein kinase inhibitors for cancer treatment
2003
Ovarian cancer
2014 Standout
Ruthenium-based chemotherapeutics: are they ready for prime time?
2010
Drug penetration in solid tumours
2006 Standout
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes
2005 Standout
A computationally engineered RAS rheostat reveals RAS–ERK signaling dynamics
2016 StandoutNobel
Raf-1 is the predominant Raf isoform that mediates growth factor-stimulated growth in ovarian cancer cells
2005
Anticancer activity of ruthenium(II) arene complexes bearing 1,2,3,4-tetrahydroisoquinoline amino alcohol ligands
2013
106Ru radiolabelling of the antitumour complex [(η6-fluorene)Ru(en)Cl]PF6
2007
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma
2003
DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media
2008
Post‐Crystal Engineering of Zinc‐Substituted Myoglobin to Construct a Long‐Lived Photoinduced Charge‐Separation System
2011 StandoutNobel
In silico evolution of substrate selectivity: comparison of organometallic ruthenium complexes with the anticancer drug cisplatin
2006
Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects
2005
Engineering the perfect (bacterial) cancer therapy
2010 Standout
Classical and novel retinoids: their targets in cancer therapy
2002
Definite coordination arrangement of organometallic palladium complexes accumulated on the designed interior surface of apo-ferritin
2010 StandoutNobel
The water soluble ruthenium(II) organometallic compound [Ru( p -cymene)(bis(3,5 dimethylpyrazol-1-yl)methane)Cl]Cl suppresses triple negative breast cancer growth by inhibiting tumor infiltration of regulatory T cells
2016
Molecular mechanisms of cisplatin resistance
2011 Standout
The Science of Antibiotic Discovery
2020 Standout
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Inflammation and Colon Cancer
2010 Standout
Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1
2011
Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice
2005
Arene Control over Thiolate to Sulfinate Oxidation in Albumin by Organometallic Ruthenium Anticancer Complexes
2009
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
2006
Mitochondrial control of cell death
2000 Standout
Identification of a Novel Retinoid by Small Molecule Screening with Zebrafish Embryos
2008
Dissecting the Role of Multiple Reductases in Bioactivation and Cytotoxicity of the Antitumor Agent 2,5-Diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone (RH1)
2008
Areneruthenium complexes as anticancer agents
2009
RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?
2001
Porous Protein Crystals as Reaction Vessels for Controlling Magnetic Properties of Nanoparticles
2012 StandoutNobel
Determining accurate molecular sizes in solution through NMR diffusion spectroscopy
2007 Standout
Bioorganometallic chemistry—from teaching paradigms to medicinal applications
2008 Standout
Ruthenation of Duplex and Single‐Stranded d(CGGCCG) by Organometallic Anticancer Complexes
2006
Raf kinases: Oncogenesis and drug discovery
2006
Half-sandwich arene ruthenium(ii )–enzyme complex
2004
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms
2005
Exploring the cellular accumulation of metal complexes
2009
Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy
2003
Eicosanoids and cancer
2010 Standout
Conformation of DNA Modified by Monofunctional Ru(II) Arene Complexes: Recognition by DNA Binding Proteins and Repair. Relationship to Cytotoxicity
2005
Medicinal Organometallic Chemistry: Designing Metal Arene Complexes as Anticancer Agents
2008
Osmium(II) and Ruthenium(II) Arene Maltolato Complexes: Rapid Hydrolysis and Nucleobase Binding
2007
Rho and Rac Take Center Stage
2004 Standout
Tumor-activated Prodrugs—A New Approach to Cancer Therapy
2004
Enhancement of colon carcinogenesis by prostaglandin E2 administration
2003
New metal complexes as potential therapeutics
2003
A new class of synthetic retinoid antibiotics effective against bacterial persisters
2018 Nature
CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway
2005
Creation of human tumour cells with defined genetic elements
1999 StandoutNature
Retinoids Regulate the Repairing Process of the Podocytes in Puromycin Aminonucleoside-induced Nephrotic Rats
2003 StandoutNobel
Tumorigenesis and the angiogenic switch
2003 Standout
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
1999
Estrogen action in human ovarian cancer
1997
Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal and malignant human ovarian surface epithelial cells.
2001
Pharmacokinetics, toxicity, and efficacy of ends-modified raf antisense oligodeoxyribonucleotide encapsulated in a novel cationic liposome.
2002
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Influence of Hydrogen-Bonding Substituents on the Cytotoxicity of RAPTA Compounds
2005
The Golden Age of Transfer Hydrogenation
2015 Standout
An Accurate Methodology to Identify the Level of Aggregation in Solution by PGSE NMR Measurements: The Case of Half-Sandwich Diamino Ruthenium(II) Salts
2005
Using coordination chemistry to design new medicines
2006
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Sensory profiling in animal models of neuropathic pain: a call for back-translation
2017
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
Tetranuclear Coordination Assemblies Based on Half-Sandwich Ruthenium(II) Complexes: Noncovalent Binding to DNA and Cytotoxicity
2009
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Ruthenium(II) half-sandwich complexes containing thioamides: Synthesis, structures and catalytic transfer hydrogenation of ketones
2012
Organometallic Anticancer Compounds
2010 Standout
Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs
2015
Metallodrugs in Medicinal Inorganic Chemistry
2014
Synthesis of Cycloruthenated Compounds as Potential Anticancer Agents
2007
Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy
2005
Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold
2014 StandoutNobel
Influence of the Diketonato Ligand on the Cytotoxicities of [Ru(η6‐p‐cymene)(R2acac)(PTA)]+ Complexes (PTA = 1,3,5‐triaza‐7‐phosphaadamantane)
2008
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
1999 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
DNA Binding and Cytotoxicity of Ruthenium(II) and Rhenium(I) Complexes of 2-Amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine
2007
Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice.
2002
The particular role of radiopharmacy within bioorganometallic chemistry
2006
Synthesis, characterization, and reactivity of ruthenium(II) complexes containing η6-arene-η1-pyrazole ligands
2012
Photocontrolled nucleobase binding to an organometallic RuII arene complex
2009
Antiestrogen Therapy Is Active in Selected Ovarian Cancer Cases: The Use of Letrozole in Estrogen Receptor–Positive Patients
2007
A Theoretical Study on the Hydrolysis Process of the Antimetastatic Ruthenium(III) Complex NAMI-A
2007
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium
1997
DNA Interactions of Monofunctional Organometallic Ruthenium(II) Antitumor Complexes in Cell-free Media
2003
Hypoxia-Sensitive Metal β-Ketoiminato Complexes Showing Induced Single-Strand DNA Breaks and Cancer Cell Death by Apoptosis
2015
Recent Developments in the Preparation and Chemistry of Metallacycles and Metallacages via Coordination
2015 Standout
The role of reductive enzymes in cancer cell resistance to mitomycin C
2000
Arene–Ruthenium(II) Acylpyrazolonato Complexes: Apoptosis-Promoting Effects on Human Cancer Cells
2014
In vivoanti-tumor activity of the organometallic ruthenium(ii )-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas
2014
Structure−Activity Relationships for Cytotoxic Ruthenium(II) Arene Complexes Containing N,N-, N,O-, and O,O-Chelating Ligands
2006
Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study
2005 Standout
Mechanism of Accumulation and Incorporation of Organometallic Pd Complexes into the Protein Nanocage of apo-Ferritin
2010 StandoutNobel
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down‐Regulation of Vascular Endothelial Growth Factor Receptor‐2 and Suppresses Tumor Growth In Vivo
2016
Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes
2012
Enzyme-Responsive Snap-Top Covered Silica Nanocontainers
2008 StandoutNobel
A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down‐Regulation of Vascular Endothelial Growth Factor Receptor‐2 and Suppresses Tumor Growth In Vivo
2016
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Organometallic Osmium(II) Arene Anticancer Complexes Containing Picolinate Derivatives
2009
Ruthenium(II) Arene Anticancer Complexes with Redox-Active Diamine Ligands
2009
Organometallic complexes that interconvert between trimeric and monomeric structures as a function of pH and their effect on human cancer and fibroblast cells
2008
Controlling ligand substitution reactions of organometallic complexes: Tuning cancer cell cytotoxicity
2005
DNA Interactions of Monofunctional Organometallic Osmium(II) Antitumor Complexes in Cell-Free Media
2008
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.
1999
Binding of Organometallic Ruthenium(II) and Osmium(II) Complexes to an Oligonucleotide: A Combined Mass Spectrometric and Theoretical Study
2005
Discovery and Investigation of Anticancer Ruthenium–Arene Schiff-Base Complexes via Water-Promoted Combinatorial Three-Component Assembly
2014
The preclinical development of regorafenib for the treatment of colorectal cancer
2014
Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis
2015
Oestrogen and progesterone receptors in ovarian carcinoma
1998
Kinetics and mechanism of the defluorination of 8-fluoropurine nucleosides in basic and acidic media
2006
Anticancer Potency Studies of Coordination Driven Self‐Assembled Arene–Ru‐Based Metalla‐Bowls
2014
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Alison Ritchie being referenced
Growth inhibition by 8-chloro cyclic AMP of human HT29 colorectal and ZR-75-1 breast carcinoma xenografts is associated with selective modulation of protein kinase A isoenzymes
1995
Growth inhibition of oestrogen receptor-positive human ovarian carcinoma by anti-oestrogens in vitro and in a xenograft model
1994
Growth-inhibitory effects of the synthetic retinoid CD437 against ovarian carcinoma models in vitro and in vivo
1998
Contrasting effects of 17 β‐estradiol on the growth of human ovarian carcinoma cells in vitro and in vivo
1993
Pharmacological and Biochemical Determinants of the Antitumour Activity of the Indoloquinone EO9
1998
Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer
2001
Tamoxifen induced apoptosis in ZR-75 breast cancer xenografts antedates tumour regression
1997
The relative importance of proliferation and cell death in breast cancer growth and response to tamoxifen
2001
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer
2002
Pharmacological determinants of the antitumour activity of mitomycin C
1998
Antitumour activity and schedule dependency of 8-chloroadenosine-3′,5′-monophosphate (8-ClcAMP) against human tumour xenografts
1998
Activity profile of the novel aziridinylbenzoquinones MeDZQ and RH1 in human tumour xenografts.
2004
Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo.
1992
Effect of matrigel on the tumorigenicity of human breast and ovarian carcinoma cell lines
1996
Does age matter? The impact of rodent age on study outcomes
2016
Functionality of the progesterone receptor in ovarian cancer and its regulation by estrogen.
1998