Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
2010
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Classical and Alternative End-Joining Pathways for Repair of Lymphocyte-Specific and General DNA Double-Strand Breaks
2012
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
2015 Standout
Sirtuins as regulators of metabolism and healthspan
2012 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Mfn2 is critical for brown adipose tissue thermogenic function
2017
The DNA-damage response in human biology and disease
2009 StandoutNature
The circadian epigenome: how metabolism talks to chromatin remodeling
2013
The molecular hallmarks of epigenetic control
2016 Standout
The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
2013
Parp‐1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells
2006
AMPK at the crossroads of circadian clocks and metabolism
2012
Nitric oxide, cell bioenergetics and neurodegeneration
2006
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance
2015
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Telomeres: history, health, and hallmarks of aging
2021
Clinical perspectives of PARP inhibitors
2005
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage
2007
Hallmarks of aging: An expanding universe
2023 Standout
Modulation of oxidative stress as an anticancer strategy
2013 Standout
NAD+ as a Signaling Molecule Modulating Metabolism
2011
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
2015
Tipping the metabolic scales towards increased longevity in mammals
2015
Sirtuins, Aging, and Metabolism
2011
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
2010
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
2010
Molecular mechanisms of cisplatin resistance
2011 Standout
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
2010 Standout
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
2005
Sirtuins and the Metabolic Hurdles in Cancer
2015
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
The roles of PARP1 in gene control and cell differentiation
2010
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
2015 StandoutNobel
Dynamics and functions of lipid droplets
2018 Standout
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
2013
Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation
2008
Mitochondria in the signaling pathways that control longevity and health span
2019
Poly(ADP-ribose): novel functions for an old molecule
2006 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
NAD+ homeostasis in health and disease
2020
The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
2012
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Metabolic Signaling to Chromatin
2015
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
PARP1-dependent Kinetics of Recruitment of MRE11 and NBS1 Proteins to Multiple DNA Damage Sites
2007
Exploring the emerging complexity in transcriptional regulation of energy homeostasis
2015
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
2012 Standout
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The Hallmarks of Aging
2013 Standout
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
Mitonuclear communication in homeostasis and stress
2016
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
2016
BubR1 is involved in regulation of DNA damage responses
2006
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
Ataxia Telangiectasia Mutated (ATM) Signaling Network Is Modulated by a Novel Poly(ADP-ribose)-dependent Pathway in the Early Response to DNA-damaging Agents
2007
Sirtuins in neurodegenerative diseases: an update on potential mechanisms
2013
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
Poly(ADP-ribose) signaling in cell death
2013
Lack of Poly(ADP-Ribose) Polymerase-1 Gene Product Enhances Cellular Sensitivity to Arsenite
2005
Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination
2009
Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
2008 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Current Development of Clinical Inhibitors of Poly(ADP-Ribose) Polymerase in Oncology
2007
Metabolic control of cell death
2014 Science
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Sirtuins, a key regulator of ageing and age-related neurodegenerative diseases
2022
Poly(ADP-Ribose)Polymerase-1 (PARP1) Controls Adipogenic Gene Expression and Adipocyte Function
2011
PARP1 Is a TRF2-associated Poly(ADP-Ribose)Polymerase and Protects Eroded Telomeres
2006
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
Spermidine in health and disease
2018 StandoutScience
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Discovery of 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors
2009
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
Mitochondrial and metabolic dysfunction in ageing and age-related diseases
2022
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin
2008
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
2010
Exploring the therapeutic space around NAD+
2012
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
2008
Works of Aline Huber being referenced
PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
2011
PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development
2004
PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure
2011
The macroPARP genes parp‐9 and parp‐14 are developmentally and differentially regulated in mouse tissues
2007
Peroxisome Proliferator-activated Receptor (PPAR)-2 Controls Adipocyte Differentiation and Adipose Tissue Function through the Regulation of the Activity of the Retinoid X Receptor/PPARγ Heterodimer
2007
Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis
2006