Citation Impact

Citing Papers

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4
2003
TRP Channels as Potential Drug Targets
2017
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Thermosensitive TRP channel pore turret is part of the temperature activation pathway
2010
Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314
2013
Clues to understanding cold sensation: Thermodynamics and electrophysiological analysis of the cold receptor TRPM8
2004
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling
2018
A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome
2010
Calcium Plays a Central Role in the Sensitization of TRPV3 Channel to Repetitive Stimulations
2008
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Lessons from peppers and peppermint: the molecular logic of thermosensation
2003 StandoutNobel
The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+ Influx and ATP Release in Primary Urothelial Cell Cultures
2009
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator
2005
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1
2003
Attenuated fever response in mice lacking TRPV1
2004
TRPV3 and TRPV4 Mediate Warmth-evoked Currents in Primary Mouse Keratinocytes
2004
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Gating of human TRPV3 in a lipid bilayer
2020
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding
2007
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Forward Genetic Analysis Reveals Multiple Gating Mechanisms of TRPV4
2010
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Transient receptor potential ion channels as participants in thermosensation and thermoregulation
2006
Unique temperature-activated neurons from pit viper thermosensors
2004
More than cool: Promiscuous relationships of menthol and other sensory compounds
2006 StandoutNobel
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
2006
Pore region of TRPV3 ion channel is specifically required for heat activation
2008 StandoutNobel
Opposite thermosensor in fruitfly and mouse
2003 StandoutNatureNobel
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels
2006
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
Cough and airway disease: The role of ion channels
2017
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Heat-evoked Activation of TRPV4 Channels in a HEK293 Cell Expression System and in Native Mouse Aorta Endothelial Cells
2002
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
2004 Nature
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Structure–functional intimacies of transient receptor potential channels
2009
2-Aminoethoxydiphenyl Borate Activates and Sensitizes the Heat-Gated Ion Channel TRPV3
2004
Targeting TRP channels for pain relief
2013
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Inflammatory status and insulin resistance
2002
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
2007 Standout
Biochemistry and pharmacology of endovanilloids
2007
A 3.5-nm Structure of Rat TRPV4 Cation Channel Revealed by Zernike Phase-contrast Cryoelectron Microscopy
2010
Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses
2004
TRPM2 activation by cyclic ADP‐ribose at body temperature is involved in insulin secretion
2006
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
2003 Standout
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli
2007
Heat Sensitization in Skin and Muscle Nociceptors Expressing Distinct Combinations of TRPV1 and TRPV2 Protein
2007
Inflammation, stress, and diabetes
2005 Standout
TRPV channels as temperature sensors
2003
Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations
2013 StandoutNobel
Modulation of the Cold-Activated Channel TRPM8 by Lysophospholipids and Polyunsaturated Fatty Acids
2007
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Rapid Temperature Jump by Infrared Diode Laser Irradiation for Patch-Clamp Studies
2009
Thermo-TRP Channels: Biophysics of Polymodal Receptors
2010
Enhanced thermal avoidance in mice lacking the ATP receptor P2X3
2005
TRP channels as cellular sensors
2003 StandoutNature
A Transient Receptor Potential Vanilloid 4-Dependent Mechanism of Hyperalgesia Is Engaged by Concerted Action of Inflammatory Mediators
2006
Gating of TRP channels: a voltage connection?
2005
Role of the Outer Pore Domain in Transient Receptor Potential Vanilloid 1 Dynamic Permeability to Large Cations
2015
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPV1
2014
Effects of Body Temperature on Neural Activity in the Hippocampus: Regulation of Resting Membrane Potentials by Transient Receptor Potential Vanilloid 4
2007
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Pyrexia is a new thermal transient receptor potential channel endowing tolerance to high temperatures in Drosophila melanogaster
2005
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Camphor Activates and Strongly Desensitizes the Transient Receptor Potential Vanilloid Subtype 1 Channel in a Vanilloid-Independent Mechanism
2005
Altered Thermal Selection Behavior in Mice Lacking Transient Receptor Potential Vanilloid 4
2005
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Sensory Nerves in Lung and Airways
2014
Irritating channels: the case of TRPA1
2010
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
TRPV channels as thermosensory receptors in epithelial cells
2005
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
2003 Nature
Mammalian somatosensory mechanotransduction
2009
Noxious heat receptors present in cold-sensory cells in rats
2004
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
Sensing with TRP channels
2005
Thermosensation and pain
2004
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
A TRPV family ion channel required for hearing in Drosophila
2003 Nature
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
2010 StandoutNobel
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Hypotonicity Induces TRPV4-Mediated Nociception in Rat
2003
The Super-Cooling Agent Icilin Reveals a Mechanism of Coincidence Detection by a Temperature-Sensitive TRP Channel
2004 StandoutNobel
Agonist-Induced Changes in Ca2+ Permeation through the Nociceptor Cation Channel TRPA1
2010
The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings
2010
Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
2009
Warm Temperatures Activate TRPV4 in Mouse 308 Keratinocytes
2003
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
2011 StandoutNobel
Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels
2009
Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels
2011
Abnormal osmotic regulation in trpv4 -/- mice
2003
Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation
2010
The ion selectivity filter is not an activation gate in TRPV1-3 channels
2019
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes
2003
Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans
2003
Keratinocytes can modulate and directly initiate nociceptive responses
2015
The TRP Superfamily of Cation Channels
2005
High‐resolution structures of transient receptor potential vanilloid channels: Unveiling a functionally diverse group of ion channels
2020
Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms
2018
A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels
2011
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Conformational plasticity in the selectivity filter of the TRPV2 ion channel
2018
TRP ION CHANNELS AND TEMPERATURE SENSATION
2006 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
PIEZO2 mediates injury-induced tactile pain in mice and humans
2018
Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel
2012
TRP Channels
2007 Standout
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel

Works of Ali D. Güler being referenced

TRPV1 shows dynamic ionic selectivity during agonist stimulation
2008
Exclusive Action of Transmembrane TNFα in Adipose Tissue Leads to Reduced Adipose Mass and Local But Not Systemic Insulin Resistance
2002
Biphasic Currents Evoked by Chemical or Thermal Activation of the Heat-gated Ion Channel, TRPV3
2005
Selective keratinocyte stimulation is sufficient to evoke nociception in mice
2015
Heat-Evoked Activation of the Ion Channel, TRPV4
2002
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