Citation Impact
Citing Papers
Delta-like 4 Notch Ligand Regulates Tumor Angiogenesis, Improves Tumor Vascular Function, and Promotes Tumor Growth In vivo
2007
2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease
2010 Standout
Adrenomedullin/Cyclic AMP Pathway Induces Notch Activation and Differentiation of Arterial Endothelial Cells From Vascular Progenitors
2006
Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition
2013
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
2014 StandoutNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate
2006
Endothelial deletion of hypoxia-inducible factor–2α (HIF-2α) alters vascular function and tumor angiogenesis
2009
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Vascular Development
2010
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
2006 StandoutNobel
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development
2006
Angiogenesis: A Team Effort Coordinated by Notch
2009
Therapeutic modulation of Notch signalling — are we there yet?
2014
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
2007
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
2006 Standout
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
2009 StandoutNobel
Eph/ephrin molecules—a hub for signaling and endocytosis
2010
Hypoxia and Inflammation
2011 Standout
Notch Signaling in the Vasculature
2010
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Notch signaling in the developing cardiovascular system
2007
Differentiation of Arterial, Venous, and Lymphatic Endothelial Cells From Vascular Progenitors
2007
Cancer stem cells revisited
2017 Standout
Scleroderma
2009 Standout
CADASIL: A Critical Look at a Notch Disease
2006
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Endothelial cells and VEGF in vascular development
2005 Nature
Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis?
2007
Genetic mouse models to study blood–brain barrier development and function
2013
Notch signalling: a simple pathway becomes complex
2006 Standout
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Three-Dimensional Analysis of Vascular Development in the Mouse Embryo
2008
The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications
2009
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
2008
Molecular regulation of angiogenesis and lymphangiogenesis
2007 Standout
Collective cell migration in morphogenesis, regeneration and cancer
2009 Standout
The Wnt/β-Catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling
2010
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
2007 Nature
EMT: 2016
2016 Standout
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
2006 Nature
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
2006 Nature
Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A
2011 StandoutNobel
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
VEGF-targeted therapy: mechanisms of anti-tumour activity
2008 Standout
VEGF and Notch Signaling
2007
Suppression of bone formation by osteoclastic expression of semaphorin 4D
2011 Standout
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Notch signalling in vertebrate neural development
2006
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Neural guidance molecules regulate vascular remodeling and vessel navigation
2005
Endothelium-Microenvironment Interactions in the Developing Embryo and in the Adult
2007
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-Like 4 Expression through AKT-mediated Activation of β-Catenin
2011
Pericytes regulate the blood–brain barrier
2010 StandoutNature
The murine allantois: emerging paradigms in development of the mammalian umbilical cord and its relation to the fetus
2007
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Modes of resistance to anti-angiogenic therapy
2008 Standout
Hedgehog Signaling Is Required for Adult Blood Stem Cell Formation in Zebrafish Embryos
2005
Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells
2009
Tumor Angiogenesis
2008 Standout
Developmental and Pathological Angiogenesis
2011
VEGF and endothelial guidance in angiogenic sprouting
2008
Control of endothelial sprouting by a Tel–CtBP complex
2010
Pericytes and vessel maturation during tumor angiogenesis and metastasis
2010
Efficient and Scalable Purification of Cardiomyocytes from Human Embryonic and Induced Pluripotent Stem Cells by VCAM1 Surface Expression
2011 StandoutNobel
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
2010 StandoutNobel
TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype
2008
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting
2007
Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells
2008 StandoutNobel
Vascular Responses to Hypoxia and Ischemia
2009 StandoutNobel
Arterial–Venous Specification During Development
2009
Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis
2010
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development
2012 StandoutNobel
Notch signaling in the mammalian central nervous system: insights from mouse mutants
2005
Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis
2008
Development of Structures and Transport Functions in the Mouse Placenta
2005
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Promoting angiogenesis to a fault
2007
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Essential Role of Endothelial Notch1 in Angiogenesis
2005
Regulation of intrathymic T‐cell development by Lunatic Fringe– Notch1 interactions
2006
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback
2005
Wound Healing: A Cellular Perspective
2018 Standout
Concise Review: Notch Signaling in Stem Cell Systems
2006
Cancer Genome Landscapes
2013 StandoutScience
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
2007
Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis
2007
Modulating the Vascular Response to Limb Ischemia
2015
Guidance of Vascular Development
2009
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch
2005
What Determines Blood Vessel Structure? Genetic Prespecification vs. Hemodynamics
2006
Delta-like 4/Notch Signaling and Its Therapeutic Implications
2007
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development
2004
The Role of Wnt Signaling in Physiological and Pathological Angiogenesis
2010
Identification and functional analysis of endothelial tip cell–enriched genes
2010
Endocardial Notch Signaling in Cardiac Development and Disease
2015
Works of Alexandre Trindade being referenced
Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli
2008
Dosage-sensitive requirement for mouse Dll4 in artery development
2004
Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos
2008
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models
2013
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion
2007