Citation Impact
Citing Papers
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations
2013
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
2016 Standout
Dynamic Single-Cell Network Profiles in Acute Myelogenous Leukemia Are Associated with Patient Response to Standard Induction Therapy
2010
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemia
2016
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia
2012
Cancer statistics, 2020
2020 Standout
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
2016
Technology platforms for pharmacogenomic diagnostic assays
2004
Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin
2004 StandoutNobel
Gene Sets Identified with Oncogene Cooperativity Analysis Regulate In Vivo Growth and Survival of Leukemia Stem Cells
2012
Cytogenetic, Molecular Genetic, and Clinical Characteristics of Acute Myeloid Leukemia With a Complex Karyotype
2008
lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1 /Suz12 Complex in the CNS
2016
A view on drug resistance in cancer
2019 StandoutNature
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
2015
Chromosome Aberrations, Gene Mutations and Expression Changes, and Prognosis in Adult Acute Myeloid Leukemia
2006
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
Neutrophilic leukocytosis in advanced stage polycythemia vera: hematopathologic features and prognostic implications
2015
The biology and management of non-small cell lung cancer
2018 StandoutNature
Sam68 Allows Selective Targeting of Human Cancer Stem Cells
2017
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
2010
SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations
2013
Origins of chromosome translocations in childhood leukaemia
2003
Precision Diagnosis and Treatment for Advanced Non–Small-Cell Lung Cancer
2017
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: recent advances
2007
High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples
2009
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Deregulation of Genes Related to Iron and Mitochondrial Metabolism in Refractory Anemia with Ring Sideroblasts
2015
p21 in cancer: intricate networks and multiple activities
2009 Standout
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
2015
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
The Cancer Cell Map Initiative: Defining the Hallmark Networks of Cancer
2015
An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
2008 Standout
Biology and management of relapsed acute myeloid leukaemia
2005
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
Development of monocytosis in patients with primary myelofibrosis indicates an accelerated phase of the disease
2012
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
2011 Standout
Transcriptional control of granulocyte and monocyte development
2007
Use of Gene-Expression Profiling to Identify Prognostic Subclasses in Adult Acute Myeloid Leukemia
2004
Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling
2005
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling
2008
TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations: Figure 1
2011
The functional contrariety of JNK
2007
Neuroblastoma
2007 Standout
Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia
2008
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy
2015
Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia
2004
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
2010 Standout
Identification of the key genes and microRNAs in adult acute myeloid leukemia with FLT3 mutation by bioinformatics analysis
2020
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data
2012
Refined medullary blast and white blood cell count based classification of chronic myelomonocytic leukemias
2014
Comprehensive Integration of Single-Cell Data
2019 Standout
A miRNA Signature of Prion Induced Neurodegeneration
2008
Simultaneous Inference in General Parametric Models
2008 Standout
The prognostic landscape of genes and infiltrating immune cells across human cancers
2015 Standout
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes
2015
Clinical and genetic predictors of prognosis in myelodysplastic syndromes
2014
TET2 Mutations Are Associated with Specific 5-Methylcytosine and 5-Hydroxymethylcytosine Profiles in Patients with Chronic Myelomonocytic Leukemia
2012
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Molecular Diagnosis of the Hematologic Cancers
2003
The cancer genome
2009 StandoutNature
DNA profiling by arrayCGH in acute myeloid leukemia and myelodysplastic syndromes
2007
Trisomy 13 is strongly associated with AML1/RUNX1 mutations and increased FLT3 expression in acute myeloid leukemia
2007
The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
2012
Inferring tumour purity and stromal and immune cell admixture from expression data
2013 Standout
MLD according to the WHO classification in AML has no correlation with age and no independent prognostic relevance as analyzed in 1766 patients
2007
Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration
2015 Standout
Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications
2011
Acute Myeloid Leukemia
2015 Standout
Chronic Myelomonocytic Leukemia
2016
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling
2003
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
2009 Standout
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?
2006
RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis
2010
Prognostic Factors and Outcome of Core Binding Factor Acute Myeloid Leukemia Patients With t(8;21) Differ From Those of Patients With inv(16): A Cancer and Leukemia Group B Study
2005
MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance
2015
Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia
2013
International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes
1997 Standout
Mutational spectrum of acute myeloid leukemia patients with double CEBPA mutations based on next-generation sequencing and its prognostic significance
2018
The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO
2007
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34− fraction
2010
Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia
2011
Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
2016
New mutations and pathogenesis of myeloproliferative neoplasms
2011
Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet
2008
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Population-based age-specific incidences of cytogenetic subgroups of acute myeloid leukemia.
2005
Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer
2021 Standout
Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for “prime time”?
2014
Diagnosing and Managing Advanced Chronic Myeloid Leukemia
2015
Genomics of chronic neutrophilic leukemia
2016
How I treat multiple myeloma in younger patients
2009
Molecular Genetics of Acute Lymphoblastic Leukemia
2005
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells
2015
Does BCR /ABL 1 positive Acute Myeloid Leukaemia Exist?
2013
High-Dose Therapy and Autologous Blood Stem-Cell Transplantation Compared With Conventional Treatment in Myeloma Patients Aged 55 to 65 Years: Long-Term Results of a Randomized Control Trial From the Group Myelome-Autogreffe
2005
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
Multiple Myeloma
2011 Standout
Minimal residual disease levels assessed by NPM1 mutation–specific RQ-PCR provide important prognostic information in AML
2009
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects
2008
Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization
2006
A Meta-Analysis of Human Embryonic Stem Cells Transcriptome Integrated into a Web-Based Expression Atlas
2007
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Gene mutations differently impact the prognosis of the myelodysplastic and myeloproliferative classes of chronic myelomonocytic leukemia
2014
World Health Organization classification in combination with cytogenetic markers improves the prognostic stratification of patients with de novo primary myelodysplastic syndromes
2007
Individual Patient Data–Based Meta-Analysis of Patients Aged 16 to 60 Years With Core Binding Factor Acute Myeloid Leukemia: A Survey of the German Acute Myeloid Leukemia Intergroup
2004
Works of Alexander Kohlmann being referenced
SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)
2012
The molecular profile of adult T‐cell acute lymphoblastic leukemia: Mutations in RUNX1 and DNMT3A are associated with poor prognosis in T‐ALL
2013
Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases
2012
Monitoring of residual disease by next-generation deep-sequencing of RUNX1 mutations can identify acute myeloid leukemia patients with resistant disease
2013
Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies
2010
Elevated c-Jun expression in acute myeloid leukemias inhibits C/EBPα DNA binding via leucine zipper domain interaction
2003
The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner
2003
Optimised Pre-Analytical Methods Improve KRAS Mutation Detection in Circulating Tumour DNA (ctDNA) from Patients with Non-Small Cell Lung Cancer (NSCLC)
2016
Current status of gene expression profiling in the diagnosis and management of acute leukaemia
2009
The role of different genetic subtypes of CEBPA mutated AML
2013
AML M3 and AML M3 variant each have a distinct gene expression signature but also share patterns different from other genetically defined AML subtypes
2005
Pediatric acute lymphoblastic leukemia (ALL) gene expression signatures classify an independent cohort of adult ALL patients
2003
Molecular characterization of acute leukemias by use of microarray technology
2003
Genomic gains and losses influence expression levels of genes located within the affected regions: a study on acute myeloid leukemias with trisomy 8, 11, or 13, monosomy 7, or deletion 5q
2005
Quantitative comparison of microarray experiments with published leukemia related gene expression signatures
2009
Prognostic relevance of RUNX1 mutations in T-cell acute lymphoblastic leukemia
2011
Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile
2005
Gene expression profiling in MDS and AML: potential and future avenues
2011
Integration of Next-Generation Sequencing Into Clinical Practice: Are We There Yet?
2012
Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status
2014
New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes
2005
TET2 deletions are a recurrent but rare phenomenon in myeloid malignancies and are frequently accompanied by TET2 mutations on the remaining allele
2011
ASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcome
2012
Gene expression profiling as a tool for the diagnosis of acute leukemias
2003
SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients
2013
Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1
2010
Identification of Differentially Expressed Genes in Scrapie-Infected Mouse Brains by Using Global Gene Expression Technology
2004
Selumetinib in combination with docetaxel as second-line treatment for patients with KRAS-mutant advanced NSCLC: Results from the phase III SELECT-1 trial
2016
Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity
2012
Association of the type of 5q loss with complex karyotype, clonal evolution, TP53 mutation status, and prognosis in acute myeloid leukemia and myelodysplastic syndrome
2014
A Multi-Center and Multi-National Program To Assess the Clinical Accuracy of the Molecular Subclassification of Leukemia by Gene Expression Profiling.
2005
Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome
2009
A novel hierarchical prognostic model of AML solely based on molecular mutations
2012
Global approach to the diagnosis of leukemia using gene expression profiling
2005
2013
Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group
2010
Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1)
2010
Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles
2002
Olaparib for Metastatic Castration-Resistant Prostate Cancer
2020
Identification of Biologically Distinct and Clinically Relevant Subentities in Patients with Acute Myeloid Leukemia and Normal Karyotypes by Use of Gene Expression Profiling.
2004
Acute lymphoblastic leukemia with low hypodiploid/near triploid karyotype is a specific clinical entity and exhibits a very high TP53 mutation frequency of 93%
2014
Detailed analysis of FLT3 expression levels in acute myeloid leukemia.
2005
Mutations of the TP53 Gene Play an Important Role in the Pathogenesis of Acute Myeloid Leukemia with Complex Aberrant Karyotype.
2004
AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features
2009
A Generic Concept for Large-scale Microarray Analysis Dedicated to Medical Diagnostics
2006
SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations
2009
Subnetwork-based analysis of chronic lymphocytic leukemia identifies pathways that associate with disease progression
2012