Citation Impact

Citing Papers

Synergistic Leukemia Eradication by Combined Treatment with Retinoic Acid and HIF Inhibition by EZN-2208 (PEG-SN38) in Preclinical Models of PML-RARα and PLZF-RARα–Driven Leukemia
2015
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
2020 StandoutNobel
Phase IIB Multicenter Trial of Vorinostat in Patients With Persistent, Progressive, or Treatment Refractory Cutaneous T-Cell Lymphoma
2007 Standout
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Translocations of the RARα gene in acute promyelocytic leukemia
2001
Engineering precision nanoparticles for drug delivery
2020 Standout
A High-Resolution STS, EST, and Gene-Based Physical Map of the Hereditary Paraganglioma Region on Chromosome 11q23
1997
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
Use of arsenic trioxide (As2O3) in the treatment of patients with acute promyelocytic leukemia
2003 Standout
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
2012 Standout
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Advances in metal-induced oxidative stress and human disease
2011 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Acute and chronic arsenic toxicity
2003 Standout
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
2001
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
2010 StandoutNature
Anticancer activities of histone deacetylase inhibitors
2006 Standout
How acute promyelocytic leukaemia revived arsenic
2002
Acquisition of Oncogenic Potential by RAR Chimeras in Acute Promyelocytic Leukemia through Formation of Homodimers
2000
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Molecular genetics of acute promyelocytic leukemia
1999
Role of the histone deacetylase complex in acute promyelocytic leukaemia
1998 Nature
Histone deacetylases and cancer: causes and therapies
2001 Standout
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Light‐Controlled Histone Deacetylase (HDAC) Inhibitors: Towards Photopharmacological Chemotherapy
2015 StandoutNobel
Oxidative Stress in Cancer
2020 Standout
Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all‐trans retinoic acid
2000
Leukaemogenesis: more than mutant genes
2009
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
2014
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
1998 StandoutNature
The particle in the spider's web: transport through biological hydrogels
2017
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray
2003 Standout
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
2001 Standout
Acute promyelocytic leukaemia: novel insights into the mechanisms of cure
2010
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Knocking down barriers: advances in siRNA delivery
2009 Standout
RNAi therapeutics: a potential new class of pharmaceutical drugs
2006
Chromatin-modifying and -remodeling complexes
1999 StandoutNobel
Deficiency in angiotensin AT1a receptors prevents diabetes-induced hypertension
2006
The Theory of APL Revisited
2007
Transcription therapy for cancer
2001
In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice
2001
Distinct interactions of PML-RARα and PLZF-RARα with co-repressors determine differential responses to RA in APL
1998
NAD + /NADH and NADP + /NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
2007 Standout
Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases
2011 Standout
NADPH Oxidases of the Brain: Distribution, Regulation, and Function
2006
Histone Acetylation Modifiers in the Pathogenesis of Malignant Disease
2000
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
2006 Standout
United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia
2001 Standout
Constitutive Expression of the Promyelocytic Leukemia–Associated Oncogene PML-RARα in TF1 Cells: Isoform-Specific and Retinoic Acid–Dependent Effects on Growth, bcl-2 Expression, and Apoptosis
1998
Genetic Diagnosis and Molecular Monitoring in the Management of Acute Promyelocytic Leukemia
1999
The Role of Oxidative Stress in Neurodegenerative Diseases
2015 Standout
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
Histone deacetylases (HDACs): characterization of the classical HDAC family
2003 Standout
Chromatin Remodeling and Leukemia: New Therapeutic Paradigms
1999
Three-dimensional organization of promyelocytic leukemia nuclear bodies
2010 StandoutNobel
Reduced Retinoic Acid-Sensitivities of Nuclear Receptor Corepressor Binding to PML- and PLZF-RARα Underlie Molecular Pathogenesis and Treatment of Acute Promyelocytic Leukemia
1998
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
2009 Standout
Histone Acetyltransferases
2001 Standout
Adult Patients With De Novo Acute Myeloid Leukemia and t(9; 11)(p22; q23) Have a Superior Outcome to Patients With Other Translocations Involving Band 11q23: A Cancer and Leukemia Group B Study
1997
Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry
2002
Transcriptional regulation in acute promyelocytic leukemia
2001
Characterization of cryptic rearrangements and variant translocations in acute promyelocytic leukemia.
1997
Nuclear Receptor Coregulators: Cellular and Molecular Biology*
1999 Standout
A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlying PLZF/RARA gene rearrangements.
2000
Mechanisms of Diabetic Complications
2013 Standout
Inhibition of Rac1-Derived Reactive Oxygen Species in Nucleus Tractus Solitarius Decreases Blood Pressure and Heart Rate in Stroke-Prone Spontaneously Hypertensive Rats
2007
Acute promyelocytic leukemia: from highly fatal to highly curable
2008
Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line
1996
The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial
1998 Standout
The World Health Organization (WHO) classification of the myeloid neoplasms
2002 Standout
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
2001
Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia
1999
Transcription Factors, Normal Myeloid Development, and Leukemia
1997

Works of Alex Chen being referenced

Mechanistic target of rapamycin is necessary for changes in dendritic spine morphology associated with long-term potentiation
2017
Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus
2015
Adenovirus-Mediated Small-Interference RNA for In Vivo Silencing of Angiotensin AT1aReceptors in Mouse Brain
2005
Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)
1995
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2026