Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
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2010 StandoutNobel
Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods
1981
Keeping the engine primed: HIF factors as key regulators of cardiac metabolism and angiogenesis during ischemia
2007
Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice
1990
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Redox Regulation of Cell Signaling by Selenocysteine in Mammalian Thioredoxin Reductases
1999
Essentiality and toxicity of selenium and its status in Australia: a review
2002
Substituent Effects in the Free Radical Reactions of Silybin: Radiation-induced Oxidation of the Flavonoid at Neutral pH
1992
Blue Light Induces Mitochondrial DNA Damage and Free Radical Production in Epithelial Cells
2005
Succinate-dependent lipid peroxidation and its prevention by reduced ubiquinone in beef heart submitochondrial particles
1992
MYC on the Path to Cancer
2012 Standout
News and views on thioredoxin reductases
1999
Flavonoids are scavengers of superoxide anions
1988
Commentary Oxidative Stress, Nutrition and Health. Experimental Strategies for Optimization of Nutritional Antioxidant Intake in Humans
1996
Antioxidant up-regulation and increased nuclear DNA protection play key roles in adaptation to oxidative stress in epithelial cells
2005
Modulation of mammalian sperm motility by quercetin
1990
Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain
2012
Preparation and assay of mammalian thioredoxin and thioredoxin reductase
1999
Selenium-Based Antihypertensives
1998
Hallmarks of aging: An expanding universe
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Human mitochondrial thioredoxin reductase
1999
A categorization of metal anticancer compounds based on their mode of action
2009
Characterization of the human heart mitochondrial proteome
2003
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Mitochondrial formation of reactive oxygen species
2003 Standout
Hydrogen Peroxide Causes Significant Mitochondrial DNA Damage in Human RPE Cells
1999
Mitochondrial permeability transition induced by dinuclear gold(I)–carbene complexes: potential new antimitochondrial antitumour agents
2004
Electrochemistry of flavonoids
1988
Human myeloperoxidase activity is inhibited in vitro by quercetin. Comparison with three related compounds
1988
Glutathione oxidase activity of selenocystamine: A mechanistic study
1992
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
Redox Signaling and the Emerging Therapeutic Potential of Thiol Antioxidants
1998
Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs
2012
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
2005 StandoutNature
Mitochondria: In Sickness and in Health
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Mitochondria, Oxidants, and Aging
2005 Standout
Mitochondrial dysfunction in human pathologies
2006
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
The biochemistry and medical significance of the flavonoids
2002 Standout
Areneruthenium complexes as anticancer agents
2009
DNA Damage and Oxygen Radical Toxicity
1988 StandoutScience
Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. III. The protective effect of antioxidants (probucol, catechin, vitamin E) against the cytotoxicity of oxidized LDL occurs in two different ways
1991
Cationic, linear Au(i) N-heterocyclic carbene complexes: synthesis, structure and anti-mitochondrial activity
2006
Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation
1989
Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin
1989 Standout
Generation of Reactive Oxygen Species in the Reaction Catalyzed by α-Ketoglutarate Dehydrogenase
2004
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
Additive pro-oxidative effects of methylmercury and ebselen in liver from suckling rat pups
2003
Physiological functions of thioredoxin and thioredoxin reductase
2000 Standout
Free Radical Scavenging and Antioxidant Activity of Plant Flavonoids
1994
Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex
2001
Free Radical Scavenging by Ethanol Extract of Propolis
1990
Inhibition of mammalian 5-lipoxygenase and cyclo-oxygenase by flavonoids and phenolic dietary additives
1991
Effects of Ebselen, a Glutathione Peroxidase Mimic, in Several Models of Mitochondrial Dysfunction
1999
The mitochondrial permeability transition
1995 Standout
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.
2001 Standout
Metal-based anticancer chemotherapeutic agents
2014
Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis
2019
Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures
1993 Standout
A thin layer chromatographic method for determining the enzymatic activity of peroxidases catalyzing the two-electron reduction of lipid hydroperoxides
2005
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Mitochondrial thioredoxin reductase in bovine adrenal cortex
1999
Essential Role of Selenium in the Catalytic Activities of Mammalian Thioredoxin Reductase Revealed by Characterization of Recombinant Enzymes with Selenocysteine Mutations
2000
Exploring metallodrug–protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound
2009
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
2011 StandoutNature
Metallomics insights into the programmed cell death induced by metal-based anticancer compounds
2014
Protection Against Reperfusion-Induced Arrhythmias by Human Thioredoxin
1996
Prevention of nitrogen mustard-induced apoptosis in normal and transformed lymphocytes by ebselen
2000
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
An overview of N-heterocyclic carbenes
2014 StandoutNature
Mice with a Homozygous Null Mutation for the Most Abundant Glutathione Peroxidase, Gpx1, Show Increased Susceptibility to the Oxidative Stress-inducing Agents Paraquat and Hydrogen Peroxide
1998
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
1999 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Oxidative stress: From basic research to clinical application
1991
Transgenic Mice Overexpressing Glutathione Peroxidase 4 Are Protected against Oxidative Stress-induced Apoptosis
2004
Synthesis, cytotoxicity, cellular uptake and influence on eicosanoid metabolism of cobalt–alkyne modified fructoses in comparison to auranofin and the cytotoxic COX inhibitor Co-ASS
2005
The permeability transition pore complex: another view
2002
Antioxidant and Chelating Properties of Flavonoids
1996
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Recent developments in ruthenium anticancer drugs
2009
The p66shc adaptor protein controls oxidative stress response and life span in mammals
1999 StandoutNature
The Mitochondrial Thioredoxin System
2000
Antioxidant Function of Thioredoxin and Glutaredoxin Systems
2000
Clinically Evaluated Cancer Drugs Inhibiting Redox Signaling
2016
Signaling Components of Redox Active Endosomes: The Redoxosomes
2008
TrxR1 as a Potent Regulator of the Nrf2-Keap1 Response System
2015
Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities
2009
SUPPRESSION OF LIPID PHOTOPEROXIDATION BY QUERCETIN AND ITS GLYCOSIDES IN SPINACH CHLOROPLASTS
1983
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Silymarin, an inhibitor of prostaglandin synthetase
1979
Oxidants, antioxidants, and the degenerative diseases of aging.
1993 Standout
Mitochondrial Transport of Cations: Channels, Exchangers, and Permeability Transition
1999
New RuIIpincer complexes: synthesis, characterization and biological evaluation for photodynamic therapy
2016
The impact of plant flavonoids on mammalian biology: implications for immunity, inflammation and cancer
2017
Protective effect of quercetin and rutin on photosensitized lysis of human erythrocytes in the presence of hematoporphyrin
1984
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations.
1990
Detection of catalase in rat heart mitochondria.
1991
A ruthenium anticancer compound interacts with histones and impacts differently on epigenetic and death pathways compared to cisplatin
2016
Antioxidants in Human Health and Disease
1996
(+)-cyanidanol-3 prevents the functional deterioration of rat liver mitochondria induced by Fe2+ ions
1986
Organometallic Anticancer Compounds
2010 Standout
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Mitochondrial formation of reactive oxygen species
2003 Standout
How mitochondria produce reactive oxygen species
2008 Standout
On the mechanism of antithrombotic action of flavonoids
1987
Effect of antiperoxidative drugs on gastric damage induced by ethanol in rats
1987
Oxidative Stress, Caloric Restriction, and Aging
1996 StandoutScience
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Oxidative Mechanisms Involved in Lignin Degradation by White-Rot Fungi
2001
Heterogenous effect of flavonoids on K+ loss and lipid peroxidation induced by oxygen-free radicals in human red cells
1986
Oxygen Activation and Oxygen Toxicity
1982
Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat
1985
Spermidine in health and disease
2018 StandoutScience
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
The Basic Biology of Redoxosomes in Cytokine-Mediated Signal Transduction and Implications for Disease-Specific Therapies
2014
On the medicinal chemistry of gold complexes as anticancer drugs
2009
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Evidence for a common selenolate intermediate in the glutathione peroxidase-like catalysis of α-(phenylselenenyl) ketones and diphenyl diselenide
1994
Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase
2014
Metabolic reprogramming and cancer progression
2020 StandoutScience
Spectrophotometric study on the oxidation of rutin by horseradish peroxidase and characteristics of the oxidized products
1986
Reaction of diphenyl diselenide with hydrogen peroxide and inhibition of delta-aminolevulinate dehydratase from rat liver and cucumber leaves
2002
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
2015
The development of RAPTA compounds for the treatment of tumors
2015
Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
2002
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
1997 Standout
O2>‐DEPENDENT and ‐INDEPENDENT PHOTOOXIDATION OF QUERCETIN IN THE PRESENCE and ABSENCE OF RIBOFLAVIN and EFFECTS OF ASCORBATE ON THE PHOTOOXIDATION
1985
Inhibition of aggregation and secretion of human platelets by quercetin and other flavonoids: Structure-activity relationships
1982
Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action
2015
Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence
2000
Enzyme inhibition by metal complexes: concepts, strategies and applications
2013
Flavonoids, a class of natural products of high pharmacological potency
1983
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
1997 StandoutNobel
In Vitro and in Vivo Evaluation of Water-Soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Breast Cancer
2014
Differential effect of silybin on the Fe2+-ADP and t-butyl hydroperoxide-induced microsomal lipid peroxidation
1986
The role of oxidative damage in the neuropathology of organic acidurias: Insights from animal studies
2004
Effects of quercetin on the gastrointestinal tract in rats and mice
1994
Polypyridyl Metal Complexes with Biological Activity
2011
The Medicinal Applications of Imidazolium Carbene−Metal Complexes
2009
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I) N-Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols
2008
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
A case of mistaken identity: are reactive oxygen species actually reactive sulfide species?
2016
The Catalytic Valorization of Lignin for the Production of Renewable Chemicals
2010 Standout
Works of Alberto Bindoli being referenced
The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria
2005
Lipid peroxidation in mitochondria
1988
Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State
2016
Gold(III)-Dithiocarbamato Complexes Induce Cancer Cell Death Triggered by Thioredoxin Redox System Inhibition and Activation of ERK Pathway
2007
Purification of Mitochondrial Thioredoxin Reductase and Its Involvement in the Redox Regulation of Membrane Permeability
1998
Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c
2003
Biochemical and toxicological properties of the oxidation products of catecholamines
1992
Effect of Spermine on Mitochondrial Glutathione Release
1993
Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells
2008
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions
2004
The role of selenium peroxidases in the protection against oxidative damage of membranes
1987
Effect of pyruvate on rat heart thiol status during ischemia and hypoxia followed by reperfusion
1993
Induction of mitochondrial permeability transition by auranofin, a Gold(I)‐phosphine derivative
2002
Antioxidant effect of manganese
1992
Effect of Auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase
2005
The mitochondrial antioxidant defence system and its response to oxidative stress
2001
Fluorescent silver(i) and gold(i)–N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights
2013
Effect of Polycation Peptides on Mitochondrial Permeability Transition
1995
Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase
2009
Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells
2006
Influence of the Redox State of Pyridine Nucleotides on Mitochondrial Sulfhydryl Groups and Permeability Transition
1997
Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, in vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands
2009
Principles in Redox Signaling: From Chemistry to Functional Significance
2012
Thiol Chemistry in Peroxidase Catalysis and Redox Signaling
2008
Modification of the xanthine-converting enzyme of perfused rat heart during ischemia and oxidative stress
1988
Inhibitory action of silymarin of lipid peroxide formation in rat liver mitochondria and microsomes
1977
Mechanisms of Cytotoxicity of Selected Organogold(III) Compounds
2005
Lipid peroxidation induced by cercosporin as a possible determinant of its toxicity
1979
Activity of Rat Cytosolic Thioredoxin Reductase Is Strongly Decreased by trans-[Bis(2-amino-5- methylthiazole)tetrachlororuthenate(III)]: First Report of Relevant Thioredoxin Reductase Inhibition for a Ruthenium Compound
2007
Inhibition of lipid peroxidation by alpha-tocopherolquinone and alpha-tocopherolhydroquinone.
1985
Mitochondrial lipid peroxidation by cumene hydroperoxide and its prevention by succinate
1982
Gold(I) Carbene Complexes Causing Thioredoxin 1 and Thioredoxin 2 Oxidation as Potential Anticancer Agents
2012
Comparative evaluation of antiperoxidative action of silymarin and other flavonoids
1978
Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs
2009
Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds
2008
Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays
2010
Inhibitory action of quercetin on xanthine oxidase and xanthine dehydrogenase activity
1985
Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes
2010
Comparison of cumene hydroperoxide- and NADPH/Fe3+/ADP-induced lipid peroxidation in heart and liver submitochondrial particles
1984