Citation Impact
Citing Papers
Molecular Dissection of Formation of Senescence-Associated Heterochromatin Foci
2007
Tissue-specific p19 Arf regulation dictates the response to oncogenic K-ras
2010
WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway
2009
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Recurrent turnover of senescent cells during regeneration of a complex structure
2015
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
2006
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation
2010
Endogenous human microRNAs that suppress breast cancer metastasis
2008 StandoutNature
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
2007
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
2011
Calorie restriction reduces rDNA recombination independently of rDNA silencing
2009
Senescence-messaging secretome: SMS-ing cellular stress
2009
A view on drug resistance in cancer
2019 StandoutNature
Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53‐dependent cellular senescence
2007
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Paradigms and pitfalls of yeast longevity research
2002
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
2012
Chromatin Modifications and Their Function
2007 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Cellular senescence: when bad things happen to good cells
2007 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Role of cellular senescence in hepatic wound healing and carcinogenesis
2012
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
2008
Pro-senescence therapy for cancer treatment
2011
The genetics of ageing
2010 StandoutNature
Downregulation of Wnt Signaling Is a Trigger for Formation of Facultative Heterochromatin and Onset of Cell Senescence in Primary Human Cells
2007
Calmodulin-mediated Activation of Akt Regulates Survival of c-Myc-overexpressing Mouse Mammary Carcinoma Cells
2004
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status
2010
Geriatric muscle stem cells switch reversible quiescence into senescence
2014 Nature
Calmodulin-binding domains: just two faced or multi-faceted?
1995
Cancer despite immunosurveillance: immunoselection and immunosubversion
2006
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
Imaging in the era of molecular oncology
2008 StandoutNature
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance
2010
A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors
2007
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
2010
Cellular Senescence in Cancer and Aging
2007 Standout
Living on a break: cellular senescence as a DNA-damage response
2008
Cellular senescence and organismal aging
2008
Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
2008
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
2006 Nature
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 StandoutNature
Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K Signaling
2009
Oncogene-Induced Cell Senescence — Halting on the Road to Cancer
2006
p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence
2009
Metabolic Control and Gene Dysregulation in Yeast Aging
2000
Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence
2007 StandoutNobel
Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
2008
The complex language of chromatin regulation during transcription
2007 StandoutNature
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
2006 Standout
Accumulation of senescent cells in mitotic tissue of aging primates
2006
Regulation of the INK4b–ARF–INK4a tumour suppressor locus: all for one or one for all
2006
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies
2018
Forging a signature of in vivo senescence
2015
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Oncogene-Induced Senescence Does Not Require the p16INK4a or p14ARF Melanoma Tumor Suppressors
2009
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
2006
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors
2006
Restoration of p53 function leads to tumour regression in vivo
2007 Nature
TGFβ and BMP signaling in cardiac cushion formation: Lessons from mice and chicken
2012
Activation of notch‐1 enhances epithelial–mesenchymal transition in gefitinib‐acquired resistant lung cancer cells
2011
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
2008 StandoutNobel
Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression
2009
The essence of senescence: Figure 1.
2010 Standout
Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
2013
PRAK Is Essential for ras-Induced Senescence and Tumor Suppression
2007
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
2010 Nature
Cellular senescence: putting the paradoxes in perspective
2010
Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis
2010
ATR signaling can drive cells into senescence in the absence of DNA breaks
2008
BRAFE600 in benign and malignant human tumours
2007
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence
2009
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
Ing1 Mediates p53 Accumulation and Chromatin Modification in Response to Oncogenic Stress
2007
Implications of Cellular Senescence in Tissue Damage Response, Tumor Suppression, and Stem Cell Biology
2008
Oncogene-induced senescence: the bright and dark side of the response
2010
Evidence that senescent human prostate epithelial cells enhance tumorigenicity: Cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT
2007
Cellular senescence and its effector programs
2014
Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging
2007
Generation, Control, and Processing of Cellular Calcium Signals
2001
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Genetic pathways that regulate ageing in model organisms
2000 Nature
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies
2012
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
The role of senescent cells in ageing
2014 StandoutNature
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
2005 StandoutNature
Tumor Stroma-Derived TGF-β Limits Myc-Driven Lymphomagenesis via Suv39h1-Dependent Senescence
2010
The Hallmarks of Aging
2013 Standout
A negative feedback signaling network underlies oncogene-induced senescence
2006
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
HIF1α delays premature senescence through the activation of MIF
2006
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
A Novel Role for High-Mobility Group A Proteins in Cellular Senescence and Heterochromatin Formation
2006
Actions of human telomerase beyond telomeres
2008
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
The Regulation of INK4/ARF in Cancer and Aging
2006
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
2003 StandoutNature
A Posttranslational Modification Cascade Involving p38, Tip60, and PRAK Mediates Oncogene-Induced Senescence
2013
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
2006 Nature
The power and the promise of oncogene-induced senescence markers
2006
Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase
2006
Genetics and biology of pancreatic ductal adenocarcinoma
2006
Involvement of MINK, a Ste20 Family Kinase, in Ras Oncogene-Induced Growth Arrest in Human Ovarian Surface Epithelial Cells
2005
Senescence in tumours: evidence from mice and humans
2009
The cancer genome
2009 StandoutNature
The role of nuclear architecture in genomic instability and ageing
2007
Cellular senescence: from physiology to pathology
2014 Standout
A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma
2010
A High Glycolytic Flux Supports the Proliferative Potential of Murine Embryonic Stem Cells
2007
Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells
2008
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
2007
Epithelial-mesenchymal transitions: insights from development
2012
Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras
2009
Oncogenic transformation and experimental models of human cancer
2007
Endocardial and Epicardial Epithelial to Mesenchymal Transitions in Heart Development and Disease
2012
Aging, Cellular Senescence, and Cancer
2012 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
2010 Standout
Lysosome-mediated processing of chromatin in senescence
2013
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Telomeres: Cancer to Human Aging
2006
Oncogene-Induced Senescence: Putting the Brakes on Tumor Development
2006
Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues
2012
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
2010
Four faces of cellular senescence
2011 Standout
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
p16INK4a Modulates p53 in Primary Human Mammary Epithelial Cells
2006
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
2008 Standout
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The Endocrine Regulation of Aging by Insulin-like Signals
2003 Science
Caenorhabditis elegans responses to bacteria from its natural habitats
2016 StandoutNobel
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
2006
Works of Alberto Benguría being referenced
Senescence in premalignant tumours
2005 Nature
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation
2010
Phosphorylation of Calmodulin by the Epidermal‐growth‐factor‐receptor Tyrosine Kinase
1994
Epigenetic stratification: the role of individual change in the biological aging process
1998
Modulation of Life-span by Histone Deacetylase Genes inSaccharomyces cerevisiae
1999
Calmodulin inhibits the epidermal growth factor receptor tyrosine kinase.
1992