Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice
2008
Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
2009
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
2008 StandoutScience
A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function
2011
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Human conditions of insulin-like growth factor-I (IGF-I) deficiency
2012
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
2014
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Myasthenia Gravis
2016 Standout
Disease-Specific Induced Pluripotent Stem Cells
2008 Standout
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
ALS: Focus on purinergic signalling
2011
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Myasthenia gravis and amyotrophic lateral sclerosis: A pathogenic overlap
2016
Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
2013
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
2007
Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
2014
Microglia in the developing brain: from immunity to behaviour
2010
Origin of Microglia: Current Concepts and Past Controversies
2015
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
2006
Microglia and neuroprotection: From in vitro studies to therapeutic applications
2010
Origin and differentiation of microglia
2013
Microglial cell origin and phenotypes in health and disease
2011 Standout
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
2013
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
2014
The Role of Immune and Inflammatory Mechanisms in ALS
2011
Non–cell autonomous effect of glia on motor neurons in an embryonic stem cell–based ALS model
2007
Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits
2011
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
2007 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
2007
Diabetic Retinopathy
2012 Standout
Factors regulating microglia activation
2013
Contribution of systemic inflammation to chronic neurodegeneration
2010
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
2012
Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1
2008
Parkinson's disease
2015 Standout
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
2008
Immunity to self and self-maintenance: what can tumor immunology teach us about ALS and Alzheimer's disease?
2008
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Autophagy as a cell-repair mechanism: Activation of chaperone-mediated autophagy during oxidative stress
2006
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
2013 Standout
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Microglia in ALS: The Good, The Bad, and The Resting
2009
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
A Fresh Look at iPS Cells
2009 StandoutNobel
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
The lipophilic metal chelators DP‐109 and DP‐460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis
2007
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
2011
Pathogenesis-Targeted, Disease-Modifying Therapies in Parkinson Disease
2013
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
2011
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Expression of Amyotrophic Lateral Sclerosis-linked SOD1 Mutant Increases the Neurotoxic Potential of Microglia via TLR2
2008
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
The antimicrobial activity of nanoparticles: present situation and prospects for the future
2017 Standout
Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
2009
Microglial Physiology: Unique Stimuli, Specialized Responses
2009
MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis
2007
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Multiple Sclerosis
2018 Standout
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
2008
Changing Face of Microglia
2010 Science
Targeting miR ‐155 restores abnormal microglia and attenuates disease in SOD 1 mice
2014
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
The Neuroinflammatory Response in ALS: The Roles of Microglia and T Cells
2012
In vivo genome editing improves motor function and extends survival in a mouse model of ALS
2017
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
2008
Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission
2011
Dysfunctional Cell-Cell Signaling in the Neurovascular Unit as a Paradigm for Central Nervous System Disease
2008
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
Microbiome–microglia connections via the gut–brain axis
2018
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice
2008
Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium.
1987 StandoutNobel
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Estrogens, Neuroinflammation, and Neurodegeneration
2016
COPPER-ZINC SUPEROXIDE DISMUTASE AND AMYOTROPHIC LATERAL SCLEROSIS
2003
The microglial-motoneuron dialogue in ALS.
2011
Works of Albert Yen being referenced
Activated Microglia Initiate Motor Neuron Injury by a Nitric Oxide and Glutamate-Mediated Mechanism
2004
Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis
2003
Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson’s disease
2006
Mutant SOD1G93A microglia are more neurotoxic relative to wild‐type microglia
2007
Nanodiamond–Gutta Percha Composite Biomaterials for Root Canal Therapy
2015
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
2006
Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis
2008