Standout Papers
- The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State (2009)
- Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome (2009)
- Modified Uridines with C5-methylene Substituents at the First Position of the tRNA Anticodon Stabilize U·G Wobble Pairing during Decoding (2008)
- Structure of the 70 S Ribosome Complexed with mRNA and tRNA (2006)
- Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines (2007)
- Crystal structure of the ribosome recycling factor bound to the ribosome (2007)
- Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome (2008)
- The termination of translation (2008)
Citation Impact
Citing Papers
Molecular Architecture of a Eukaryotic Translational Initiation Complex
2013 ScienceNobel
Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance
2008
Crystal Structure of the Eukaryotic 40 S Ribosomal Subunit in Complex with Initiation Factor 1
2010 Science
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity
2007 StandoutNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
Structure of the Yeast Mitochondrial Large Ribosomal Subunit
2014 ScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Crystal Structure of the Eukaryotic Ribosome
2010 Science
Structures of the Bacterial Ribosome at 3.5 A Resolution
2005 Science
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes
2008
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
2012 Standout
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
The Structure and Function of the Eukaryotic Ribosome
2012
mRNA translocation occurs during the second step of ribosomal intersubunit rotation
2011
A sequence element that tunes Escherichia coli tRNAAlaGGC to ensure accurate decoding
2009
Atomic structures of the eukaryotic ribosome
2012
Crosslinking of Translation Factor EF-G to Proteins of the Bacterial Ribosome Before and After Translocation
2007
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Kinetically Competent Intermediates in the Translocation Step of Protein Synthesis
2007
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
The Ribosomal Peptidyl Transferase
2007
Accommodation of aminoacyl-tRNA into the ribosome involves reversible excursions along multiple pathways
2010
A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis
2008
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
2007
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
2008 StandoutNobel
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments
2008
Coupling of Ribosomal L1 Stalk and tRNA Dynamics during Translation Elongation
2008
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
GTPase activation of elongation factor EF‐Tu by the ribosome during decoding
2009 StandoutNobel
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
A hierarchical model for evolution of 23S ribosomal RNA
2009 Nature
A fast dynamic mode of the EF‐G‐bound ribosome
2009
Molecular dynamics of EF‐G during translocation
2011 StandoutNobel
Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)
2013 StandoutNobel
Structural insights into cognate versus near‐cognate discrimination during decoding
2011 StandoutNobel
The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole
2007 StandoutNobel
Viral IRES RNA structures and ribosome interactions
2008
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy
2010 Nature
A structural understanding of the dynamic ribosome machine
2008 StandoutNobel
Structure and Dynamics of the Mammalian Ribosomal Pretranslocation Complex
2011
Structures of the human and Drosophila 80S ribosome
2013 Nature
Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
2013 StandoutNobel
Evolution of Elongation Factor G and the Origins of Mitochondrial and Chloroplast Forms
2010
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Correlating ribosome function with high-resolution structures
2008 StandoutNobel
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
2009 StandoutNobel
Aminoglycoside activity observed on single pre-translocation ribosome complexes
2009
Structure of the Base of the L7/L12 Stalk of the Haloarcula marismortui Large Ribosomal Subunit: Analysis of L11 Movements
2007 StandoutNobel
Structural dynamics of the ribosome
2008
Navigating the ribosome's metastable energy landscape
2009
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Structural rearrangements of the ribosome at the tRNA proofreading step
2010
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Structure of the ternary initiation complex aIF2–GDPNP–methionylated initiator tRNA
2012
Single-Molecule Fluorescence Measurements of Ribosomal Translocation Dynamics
2011
Assembly and Analysis of Eukaryotic Translation Initiation Complexes
2007
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Genetic identification of yeast 18S rRNA residues required for efficient recruitment of initiator tRNAMet and AUG selection
2008
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Progression of the Ribosome Recycling Factor through the Ribosome Dissociates the Two Ribosomal Subunits
2007
Structural basis for translation termination by archaeal RF1 and GTP-bound EF1α complex
2012
Observation of Intersubunit Movement of the Ribosome in Solution Using FRET
2007
Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics
2008 StandoutNobel
Two-step model of stop codon recognition by eukaryotic release factor eRF1
2013
Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome
2008 StandoutNobel
Identification of Two Distinct Hybrid State Intermediates on the Ribosome
2007
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
2009 StandoutNobel
Peptide‐Bond Synthesis on the Ribosome: No Free Vicinal Hydroxy Group Required on the Terminal Ribose Residue of Peptidyl‐tRNA
2008
Energy barriers and driving forces in tRNA translocation through the ribosome
2013
Spontaneous Intersubunit Rotation in Single Ribosomes
2008
Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits
2007 StandoutNobel
Spontaneous reverse movement of mRNA-bound tRNA through the ribosome
2007
The Role of L1 Stalk–tRNA Interaction in the Ribosome Elongation Cycle
2010
Heterogeneity of Large Macromolecular Complexes Revealed by 3D Cryo-EM Variance Analysis
2008
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
2010 Nature
Stochastic kinetics of ribosomes: Single motor properties and collective behavior
2009
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu
2009 StandoutNobel
Structural insights into eRF3 and stop codon recognition by eRF1
2009
Translation factors direct intrinsic ribosome dynamics during translation termination and ribosome recycling
2009
Correlated conformational events in EF-G and the ribosome regulate translocation
2010
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Structure of the no-go mRNA decay complex Dom34–Hbs1 bound to a stalled 80S ribosome
2011
Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2
2013
Structure of the 30S translation initiation complex
2008 Nature
Following translation by single ribosomes one codon at a time
2008 Nature
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
2007
Structural basis for translation termination on the 70S ribosome
2008 Nature
tRNA–mRNA mimicry drives translation initiation from a viral IRES
2007
Termination and post-termination events in eukaryotic translation
2012
Cross-crystal averaging reveals that the structure of the peptidyl-transferase center is the same in the 70S ribosome and the 50S subunit
2008 StandoutNobel
Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome
2010 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution
2010
Structures of the Ribosome in Intermediate States of Ratcheting
2009 Science
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel
Structural characterization of mRNA-tRNA translocation intermediates
2012 StandoutNobel
A Click Chemistry Approach to Pleuromutilin Conjugates with Nucleosides or Acyclic Nucleoside Derivatives and Their Binding to the Bacterial Ribosome
2008
Integrity of the P-site is probed during maturation of the 60S ribosomal subunit
2012 StandoutNobel
Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding
2011 Science
Spontaneous formation of the unlocked state of the ribosome is a multistep process
2009
Crystal structure of a translation termination complex formed with release factor RF2
2008
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
Ribosomal Translocation: One Step Closer to the Molecular Mechanism
2009
The Mechanism for Activation of GTP Hydrolysis on the Ribosome
2010 ScienceNobel
Structural basis for TetM-mediated tetracycline resistance
2012
Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles
2013
Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3
2011 Nobel
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Irreversible chemical steps control intersubunit dynamics during translation
2008
Transfer RNA in the hybrid P/E state: Correlating molecular dynamics simulations with cryo-EM data
2007 StandoutNobel
Structural basis for cross-resistance to ribosomal PTC antibiotics
2008 StandoutNobel
Crystal Structure of the Eukaryotic 60 S Ribosomal Subunit in Complex with Initiation Factor 6
2011 Science
Following movement of the L1 stalk between three functional states in single ribosomes
2009
Role of Ribosomal Protein L27 in Peptidyl Transfer
2008
Ribosome Structure and Dynamics During Translocation and Termination
2010
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation
2011 StandoutNobel
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome
2010
The process of mRNA–tRNA translocation
2007 StandoutNobel
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
2008
Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
2008 StandoutNobel
Acquisition of a natural resistance gene renders a clinical strain of methicillin‐resistantStaphylococcus aureusresistant to the synthetic antibiotic linezolid
2007
Fidelity at the Molecular Level: Lessons from Protein Synthesis
2009
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation
2009
Works of Albert Weixlbaumer being referenced
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome
2008 StandoutScienceNobel
Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome
2009 StandoutNobel
The termination of translation
2008 StandoutNobel
Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines
2007 StandoutNobel
Crystal structure of the ribosome recycling factor bound to the ribosome
2007 StandoutNobel
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel