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Citing Papers
Pten Deficiency Activates Distinct Downstream Signaling Pathways in a Tissue-Specific Manner
2006
Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas
2008
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice
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Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila
2002
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
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Hallmarks of Cancer: The Next Generation
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High-Grade Glioma Formation Results from Postnatal Pten Loss or Mutant Epidermal Growth Factor Receptor Expression in a Transgenic Mouse Glioma Model
2006
S6k1 is not required for Pten-deficient neuronal hypertrophy
2006
Inflammation and cancer
2002 StandoutNature
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Making a tumour's bed: glioblastoma stem cells and the vascular niche
2007
Molecular domains of myelinated axons
2000
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
Ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice
2007
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
2006 Standout
A Splice Code for trans-Synaptic Cell Adhesion Mediated by Binding of Neuroligin 1 to α- and β-Neurexins
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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
2006 Standout
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
1988 StandoutNobel
Use of transgenic mice to study voltage-dependent Ca2+ channels
2001
Dystroglycan: important player in skeletal muscle and beyond
2005
Intravital imaging of cell movement in tumours
2003
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
2006 Nature
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Transgenic Mice and Oncogenesis
1988
The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1
1992
Astrocyte barriers to neurotoxic inflammation
2015
Predominant Functional Expression of Kv1.3 by Activated Microglia of the Hippocampus after Status epilepticus
2009
Evidence That Dystroglycan Is Associated with Dynamin and Regulates Endocytosis
2005
When Checkpoints Fail
1997 StandoutNobel
Status Epilepticus Induces a Particular Microglial Activation State Characterized by Enhanced Purinergic Signaling
2008
Protein glycosylation in disease: new insights into the congenital muscular dystrophies
2003
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
2003 Standout
Glial connexins and gap junctions in CNS inflammation and disease
2008
Visualization of microglia in living tissues using Iba1‐EGFP transgenic mice
2005
Neurexin–neuroligin signaling in synapse development
2007
Disruption of Dag1 in Differentiated Skeletal Muscle Reveals a Role for Dystroglycan in Muscle Regeneration
2002
Variable Threshold of Trigeminal Cold-Thermosensitive Neurons Is Determined by a Balance between TRPM8 and Kv1 Potassium Channels
2009
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
2009 Standout
Induction of angiogenesis during the transition from hyperplasia to neoplasia
1989 StandoutNature
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
2011 Nature
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
Defective glycosylation in congenital muscular dystrophies
2004
An Extracellular Pathway for Dystroglycan Function in Acetylcholine Receptor Aggregation and Laminin Deposition in Skeletal Myotubes
2006
The dystroglycan complex: From biology to cancer
2005
Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells
2012
CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation
2009
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model
2009
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
The zebrafish as a model for muscular dystrophy and congenital myopathy
2003
The ectonucleotidase cd39/ENTPDase1 modulates purinergic‐mediated microglial migration
2007
Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis
2010
Targeting Dystroglycan in the Brain
2003
Glial cells generate neurons: the role of the transcription factor Pax6
2002
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
2008 StandoutNobel
Neuronal ‘On’ and ‘Off’ signals control microglia
2007
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
1990
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
2003
Post-translational disruption of dystroglycan–ligand interactions in congenital muscular dystrophies
2002 Nature
Tumor Spectrum, Tumor Latency and Tumor Incidence of the Pten-Deficient Mice
2007
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
1990 StandoutNatureNobel
Molecular tuning of electroreception in sharks and skates
2018 StandoutNatureNobel
Neurexins Induce Differentiation of GABA and Glutamate Postsynaptic Specializations via Neuroligins
2004
Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma
2011
Lipopolysaccharide‐induced down‐regulation of Ca2+release‐activated Ca2+currents (ICRAC) but not Ca2+‐activated TRPM4‐like currents (ICAN) in cultured mouse microglial cells
2007
Defective glycosylation in muscular dystrophy
2002
Structure of human phenylethanolamine n-methyltransferase gene: existence of two types of mRNA with different transcription initiation sites
1989
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
βIV Spectrins Are Essential for Membrane Stability and the Molecular Organization of Nodes of Ranvier
2004
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
2007 StandoutNobel
Mouse gastrulation: the formation of a mammalian body plan
1997
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Glycobiology of neuromuscular disorders
2003
A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
2004 Standout
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Alpha‐dystroglycan interactions affect cerebellar granule neuron migration
2004
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Atrial Natriuretic Factor-SV40 T Antigen Transgenes Produce Tumors and Cardiac Arrhythmias in Mice
1988 Science
GERM-LINE TRANSFORMATION OF MICE
1986
Detection of targeted GFP - Hox gene fusions during mouse embryogenesis
1998 StandoutNobel
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
1985 Nature
Human erythropoietin gene expression in transgenic mice: multiple transcription initiation sites and cis-acting regulatory elements.
1990 StandoutNobel
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Dissecting Multistep Tumorigenesis in Transgenic Mice
1988
Dystroglycan: from biosynthesis to pathogenesis of human disease
2006
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
A p53-Dependent Mouse Spindle Checkpoint
1995 Science
Insulin Hypersensitivity and Resistance to Streptozotocin-Induced Diabetes in Mice Lacking PTEN in Adipose Tissue
2005
Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland
2002
Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
1987
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
1986 StandoutNatureNobel
Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA.
1990
Dystroglycan Is Selectively Associated with Inhibitory GABAergic Synapses But Is Dispensable for Their Differentiation
2002
Molecular mechanism for depolarization-induced modulation of Kv channel closure
2012
Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.
1991
Glycobiology: Toward Understanding the Function of Sugars
1996 Standout
Prostate cancer in a transgenic mouse.
1995 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Transgenic Models of Tumor Development
1991 Science
Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector.
1985
Developmental Regulation of Nicotinic Acetylcholine Receptors
1987
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1cell cycle entry
2005
Dystroglycan loss disrupts polarity and β-casein induction in mammary epithelial cells by perturbing laminin anchoring
2006
Viruses in Human Cancers
1991 StandoutScienceNobel
Multiple Regulatory Domains in the Mouse Mammary Tumor Virus Long Terminal Repeat Revealed by Analysis of Fusion Genes in Transgenic Mice
1988
Human Erythropoietin Gene Expression in Transgenic Mice: Multiple Transcription Initiation Sites and cis-Acting Regulatory Elements
1990 StandoutNobel
Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice.
1988
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development
1986
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
2004
Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes
1984
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene.
1989
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene
1987
Selective Deletion of Pten in Pancreatic β Cells Leads to Increased Islet Mass and Resistance to STZ-Induced Diabetes
2006
Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast‐derived iPS cells using zinc‐finger nuclease technology
2015
cDNA cloning of a serotonin 5-HT1C receptor by electrophysiological assays of mRNA-injected Xenopus oocytes.
1987
Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.
1993
Regulation of insulin-like growth factor I gene expression by growth hormone.
1986
Transforming Growth Factor Alpha Dramatically Enhances Oncogene-Induced Carcinogenesis in Transgenic Mouse Pancreas and Liver
1993
Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
1985 Nature
Physiology of Microglia
2011 Standout
Works of Albee Messing being referenced
Sleep in Kcna2 knockout mice
2007
Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy
2002 Nature
GFAP promoter elements required for region‐specific and astrocyte‐specific expression
2008
Immortalized retinal neurons derived from SV40 T-antigen-induced tumors in transgenic mice
1990
Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease
2001
Seizures and Reduced Life Span in Mice Lacking the Potassium Channel Subunit Kv1.2, but Hypoexcitability and Enlarged Kv1 Currents in Auditory Neurons
2007
Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain
2004
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
2005
The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia
2006
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways
2008
Astrocytes: a central element in neurological diseases
2015
Unique Role of Dystroglycan in Peripheral Nerve Myelination, Nodal Structure, and Sodium Channel Stabilization
2003
Cre/loxP‐mediated inactivation of the murine Pten tumor suppressor gene
2002
hGFAP‐cre transgenic mice for manipulation of glial and neuronal function in vivo
2001
Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvβ2, and Caspr
1999
Live Astrocytes Visualized by Green Fluorescent Protein in Transgenic Mice
1997
Alexander Disease
2012
Temperature-Sensitive Neuromuscular Transmission in Kv1.1 Null Mice: Role of Potassium Channels under the Myelin Sheath in Young Nerves
1998
Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice
1985 Nature
Extra-synaptic localization of α-bungarotoxin receptors in cultured chick ciliary ganglion neurons
1983
Conditional Ablation of Cerebellar Astrocytes in Postnatal Transgenic Mice
1996
Transgenic analysis of GFAP promoter elements
2013
PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization
2005
Determinants of Excitability at Transition Zones in Kv1.1-Deficient Myelinated Nerves
1999
Transgenic mice harboring SV40 t-antigen genes develop characteristic brain tumors
1984
Neurological Diseases as Primary Gliopathies: A Reassessment of Neurocentrism
2012
SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice
1985 Nature
Developmental study of SV40 large T antigen expression in transgenic mice with choroid plexus neoplasia.
1988
Elastase I Promoter Directs Expression of Human Growth Hormone and SV40 T Antigen Genes to Pancreatic Acinar Cells in Transgenic Mice
1985
Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina.
1988
Accelerated Hippocampal Spreading Depression and Enhanced Locomotory Activity in Mice with Astrocyte-Directed Inactivation of Connexin43
2003
Heart and bone tumors in transgenic mice.
1988
Absence of the β subunit ( cchb1 ) of the skeletal muscle dihydropyridine receptor alters expression of the α 1 subunit and eliminates excitation-contraction coupling
1996
Pancreatic Neoplasia Induced by SV40 T-Antigen Expression in Acinar Cells of Transgenic Mice
1987 Science