Citation Impact
Citing Papers
Human Papillomavirus 16 E5 Oncogene Contributes to Two Stages of Skin Carcinogenesis
2007
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Mdm2 promotes the rapid degradation of p53
1997 StandoutNature
Regulation of p53 stability by Mdm2
1997 StandoutNature
Transcription of the transforming genes of the oncogenic human papillomavirus-16 is stimulated by tumor promotors through AP1 binding sites
1990
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
2000 StandoutNobel
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
The human papillomavirus E7 protein as a transforming and transactivating factor
1993
p53 in growth control and neoplasia
1996
Papillomaviruses Causing Cancer: Evasion From Host-Cell Control in Early Events in Carcinogenesis
2000 Standout
Functional regulation of p73 and p63: development and cancer
2003
Human papillomavirus oncoproteins: pathways to transformation
2010 Standout
Epithelial Malignancies in Organ Transplant Patients: Clinical Presentation and New Methods of Treatment
2002
A novel cis-stimulatory element maps to the 5' portion of the human papillomavirus type 18 upstream regulatory region and is functionally dependent on a sequence-aberrant Sp1 binding site
1993
Papillomavirus infections — a major cause of human cancers
1996 StandoutNobel
p53 CODON 72 POLYMORPHISM AND SUSCEPTIBILITY TO SKIN CANCER AFTER RENAL TRANSPLANTATION
2000
The Genetics of Sun Sensitivity in Humans
2004
Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals
2000
Properties of a non‐tumorigenic human cervical keratinocyte cell line
1989
Basic mechanisms of high‐risk human papillomavirus‐induced carcinogenesis: Roles of E6 and E7 proteins
2007
Immortalization of human cells and their malignant conversion by high risk human papillomavirus genotypes
1999 StandoutNobel
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Expression of RB and p53 proteins in HPV‐positive and HPV‐negative cervical carcinoma cell lines
1991
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1990 Standout
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Viral proteins containing the purine NTP-binding sequence pattern
1989
Characterization of in vivo expression of the human papillomavirus type 16 E4 protein in cervical biopsy tissues.
1991
The Hallmarks of Cancer
2000 Standout
The role of the E6-p53 interaction in the molecular pathogenesis of HPV
1999
The p53 pathway
1999
Glucocorticoid-dependent oncogenic transformation by type 16 but not type 11 human papilloma virus DNA
1988 Nature
Oncogenic activities of human papillomaviruses
2009
Skin Cancers after Organ Transplantation
2003 Standout
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
The Human Papillomavirus Type 16 E6 and E7 Oncoproteins Dissociate Cellular Telomerase Activity from the Maintenance of Telomere Length
1997
The human papillomavirus E7 oncoprotein
2008
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
The human papillomavirus (HPV)-6 and HPV-16 E5 proteins co-operate with HPV-16 E7 in the transformation of primary rodent cells
1995
Specific interaction between HPV-16 E1–E4 and cytokeratins results in collapse of the epithelial cell intermediate filament network
1991 Nature
The p53 tumour suppressor gene
1991 StandoutNature
p53 codon 72 Pro homozygosity increases the risk of cutaneous melanoma in individuals with dark skin complexion and among noncarriers of melanocortin 1 receptor red hair variants
2006
Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion
2001
Mechanisms of cell transformation by papillomavirus E5 proteins
2001
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
Cytogenetic analysis of eight human papillomavirus immortalized human keratinocyte cell lines
1989
Papillomavirus E6 proteins
2008
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
Degradation of p53 only is not sufficient for the growth stimulatory effect of human papillomavirus 16 E6 oncoprotein in human embryonic fibroblasts
1994
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Human papillomavirus type 16 and 18 gene expression in cervical neoplasias
1992
Detection of novel splicing patterns in a HPV16-containing keratinocyte cell line
1990
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
The Emerging p53 Gene Family
1999 StandoutNobel
Changes in the physical state and expression of human papillomavirus type 16 in the progression of cervical intraepithelial neoplasia lesions analysed by PCR
1995
Jun-B oncogene aberrations in cervical cancer cell lines
1995
Human Papillomavirus DNA and p53 Polymorphisms in Squamous Cell Carcinomas From Fanconi Anemia Patients
2003
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth
1999
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Cancer Dissemination—Lessons from Leukocytes
2010
Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer
2003 Standout
Cellular transformation by papilomavirus oncorproteins
1993
TP53 Polymorphism of Exon 4 at Codon 72 in Cutaneous Squamous Cell Carcinoma and Benign Epithelial Lesions of Renal Transplant Recipients and Immunocompetent Individuals: Lack of Correlation with Human Papillomavirus Status11This work was presented in part at the 19th International Papillomavirus Conference in Florianopolis, Brazil, September 1–7, 2001.
2002
Human papillomavirus type 16 E6 proteins with glycine substitution for cysteine in the metal-binding motif
1991
Modulation of apoptosis by human papillomavirus (HPV) oncoproteins
2006
RecBCD Enzyme and the Repair of Double-Stranded DNA Breaks
2008
p53 Mutations in Human Cancers
1991 StandoutScience
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development.
1994
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Progression of human papillomavirus type 18-immortalized human keratinocytes to a malignant phenotype.
1991
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Transforming growth factors beta 1 and 2 transcriptionally regulate human papillomavirus (HPV) type 16 early gene expression in HPV-immortalized human genital epithelial cells
1990
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.
1991
Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ-ras.
1989
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.
1989
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Microarray Analysis Identifies Interferon-Inducible Genes and Stat-1 as Major Transcriptional Targets of Human Papillomavirus Type 31
2000
The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells
1991
A Role for HPV16 E5 in Cervical Carcinogenesis
2010
Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes
1992
Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes.
1995
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
2000 Standout
HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.
1989 Standout
Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein
2000
Homologous recombination in procaryotes
1988
The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein
1993
Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins.
1992
Human papillomavirus type 16 transformation of primary human embryonic fibroblasts requires expression of open reading frames E6 and E7
1989
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
1989 Standout
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Effects of Intercistronic Length on the Efficiency of Reinitiation by Eucaryotic Ribosomes
1987
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Surfing the p53 network
2000 StandoutNature
Viruses in Human Cancers
1991 StandoutScienceNobel
Effect of human papillomavirus type 16 oncogenes on MAP kinase activity
1995
Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism
1991
A member of the activator protein 1 family found in keratinocytes but not in fibroblasts required for transcription from a human papillomavirus type 18 promoter
1990
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
Papillomavirus E6 and E7 proteins and their cellular targets
2007
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters
1990
Human papillomavirus type 16 E5 protein affects cell-cell communication in an epithelial cell line
1995
Interaction of Papillomavirus E6 Oncoproteins with a Putative Calcium-Binding Protein
1995 Science
Immortalization of human foreskin keratinocytes by various human papillomavirus DNAs corresponds to their association with cervical carcinoma
1989
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Influence of chromosomal integration on glucocorticoid-regulated transcription of growth-stimulating papillomavirus genes E6 and E7 in cervical carcinoma cells.
1991 StandoutNobel
Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein.
1990
Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae
1988
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Progesterone and glucocorticoid response elements occur in the long control regions of several human papillomaviruses involved in anogenital neoplasia
1989
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
A Genomic Perspective on Protein Families
1997 StandoutScience
Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein
1992
Skin cancer chemoprophylaxis in renal transplant recipients: 5 years of experience using low-dose acitretin
1999
Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53
1990 StandoutScience
Direct Activation of Cyclin-Dependent Kinase 2 by Human Papillomavirus E7
2003
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product
1989 StandoutScience
Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP.
1988
Bap31 Is a Novel Target of the Human Papillomavirus E5 Protein
2008
Works of Alan Storey being referenced
Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen
2009
HPV-16 E7 and adenovirus E1a complex formation with TATA box binding protein is enhanced by casein kinase II phosphorylation.
1996
HPV‐associated skin disease
2005
The Human Papillomavirus Type 16 E5 Gene Cooperates with the E7 Gene to Stimulate Proliferation of Primary Cells and Increases Viral Gene Expression
1994
Mutations of the human papillomavirus type 16 E7 gene that affect transformation, transactivation and phosphorylation by the E7 protein
1990
Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria
2006
Anti-sense phosphorothioate oligonucleotides have both specific and non-specific effects on cells containing human papillomavirus type 16
1991
E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia
2002
Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer
1998 Nature
Co-transformation by Human Papillomavirus Types 6 and 11
1990
p53 codon 72 polymorphism and risk of cervical cancer in UK
1998
Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins
2000
Identification of the regions of the HPV 5 E6 protein involved in Bak degradation and inhibition of apoptosis
2008
Relationship Between p53 Codon 72 Polymorphism and Susceptibility to Sunburn and Skin Cancer
2002
Comparison of the in vitro transforming activities of human papillomavirus types.
1988
Complete nucleotide sequence of theEscherichia coli recBgene
1986
p53 polymorphism and risk of cervical cancer
1998 Nature
Mutational analysis of HPV-18 E6 identifies domains required for p53 degradation in vitro, abolition of p53 transactivation in vivo and immortalisation of primary BMK cells.
1994
Role of human papillomaviruses in cutaneous and oral manifestations of immunosuppression.
1999
Human papillomavirus type 16 cooperates with activated ras and fos oncogenes in the hormone-dependent transformation of primary mouse cells.
1988
Characterization of the human papillomavirus E2 protein: evidence of trans-activation and trans-repression in cervical keratinocytes.
1994
Complete nucleotide sequence ofrecD, the structural gene for the α subunit of Exonuclease V ofEscherichia coli
1986
Human papillomavirus type 16 E6 gene cooperates with EJ-ras to immortalize primary mouse cells.
1993
Conditional immortalization of primary cells by human papillomavirus type 18 E6 and EJ-ras defines an E6 activity in G0/G1 phase which can be substituted for mutations in p53.
1995
p53 polymorphism in codon 72 and risk of human papillomavirus-induced cervical cancer: effect of inter-laboratory variation
2000