Citation Impact
Citing Papers
Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage
2006
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals
2021 StandoutNobel
Limits of long-term selection against Neandertal introgression
2019 StandoutNobel
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
2015
Roles of tau protein in health and disease
2017
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
2012
Tau Isoform Composition Influences Rate and Extent of Filament Formation
2012
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
2015
Genomewide Association Studies and Human Disease
2009
Transcriptional Regulation and Its Misregulation in Disease
2013
Recent advances in our understanding of neurodegeneration
2009
SIFT web server: predicting effects of amino acid substitutions on proteins
2012 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Evidence for archaic adaptive introgression in humans
2015
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
A Haplotype at STAT2 Introgressed from Neanderthals and Serves as a Candidate of Positive Selection in Papua New Guinea
2012
The genomic landscape of Neanderthal ancestry in present-day humans
2014 StandoutNatureNobel
Alzheimer's disease
2011 Standout
Glycogen synthase kinase‐3β and tau genes interact in Alzheimer's disease
2008
The emerging role of lncRNAs in cancer
2015 Standout
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
2015 Standout
Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation inalpha2‐macroglobulinandtau: A population‐based autopsy study
2008
Voxel-based morphometry in autopsy proven PSP and CBD
2006
Neurodegenerative Diseases Target Large-Scale Human Brain Networks
2009 Standout
The Human Transcription Factors
2018 Standout
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
2008 Standout
Parkinson's disease
2009 Standout
Neuropathology of Frontotemporal Lobar Degeneration-Tau (FTLD-Tau)
2011
Tau in physiology and pathology
2015 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
The origins and impact of primate segmental duplications
2009
Antisense Reduction of Tau in Adult Mice Protects against Seizures
2013
A clinico-pathological study of subtypes in Parkinson's disease
2009
Williams–Beuren Syndrome
2010 Standout
Wnt/β-Catenin Signaling and Disease
2012 Standout
Parkinson's disease
2015 Standout
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses
2008
Autophagy in Human Health and Disease
2013 Standout
The diverse origins of the human gene pool
2015 StandoutNobel
Systemic amyloidosis
2015 Standout
Advances in the genetics of Parkinson disease
2013
Alzheimer's disease
2016 Standout
The propagation of prion-like protein inclusions in neurodegenerative diseases
2010
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
2011
Bonobos Fall within the Genomic Variation of Chimpanzees
2011 StandoutNobel
Alzheimer's Disease
2010 Standout
Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration
2009
Genome-Wide Copy Number Variation in Epilepsy: Novel Susceptibility Loci in Idiopathic Generalized and Focal Epilepsies
2010
Clinical outcomes of progressive supranuclear palsy and multiple system atrophy
2008
Fine-scale recombination patterns differ between chimpanzees and humans
2005 StandoutNobel
The diverse roles of IRF4 in late germinal center B‐cell differentiation
2012
Genomic Rearrangements and Gene Copy-Number Alterations as a Cause of Nervous System Disorders
2006
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The Amyloid State of Proteins in Human Diseases
2012 Standout
The Phyre2 web portal for protein modeling, prediction and analysis
2015 Standout
Beyond GWASs: Illuminating the Dark Road from Association to Function
2013
Parkinson's Disease and Parkinsonism: Neuropathology
2012
Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors
2008
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech
2006
Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series
2013
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
The Human Condition—A Molecular Approach
2014 StandoutNobel
Tau Kinetics in Neurons and the Human Central Nervous System
2018
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Biological fluid biomarkers in neurodegenerative parkinsonism
2009
Copy number variation at the 7q11.23 segmental duplications is a susceptibility factor for the Williams-Beuren syndrome deletion
2008
Functional MAPT haplotypes: Bridging the gap between genotype and neuropathology
2007
The genetics of P arkinson's disease: Progress and therapeutic implications
2013
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
2010 Standout
Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans
2014 StandoutNobel
A Century of Alzheimer's Disease
2006 StandoutScience
KEGG: integrating viruses and cellular organisms
2020 Standout
Mutations causing neurodegenerative tauopathies
2004
Lessons from Functional Analysis of Genome-Wide Association Studies
2013
Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial
2014
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Whole-Genome Patterns of Common DNA Variation in Three Human Populations
2005 Science
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
2011 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Alzheimer'S Disease: Advances In Genetics, Molecular And Cellular Biology
2007
Emerging Targets in Photopharmacology
2016 StandoutNobel
Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
2013
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Parkinson's Disease: Genetics and Pathogenesis
2011
Works of Alan Pittman being referenced
Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome
2007
The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features
2012
The tau H2 haplotype is almost exclusively Caucasian in origin
2004
Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism
2005
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
2006
The structure of the tau haplotype in controls and in progressive supranuclear palsy
2004
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration
2005
The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4
2011
Evaluation of germline BMP4 mutation as a cause of colorectal cancer
2010
MAPT S305I mutation: implications for argyrophilic grain disease
2007
Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of EIF3H
2010
Clinical and pathological features of an Alzheimer's disease patient with the MAPT ΔK280 mutation
2007
The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
2005
Untangling the tau gene association with neurodegenerative disorders
2006
Fine-scale mapping of the 6p25.3 chronic lymphocytic leukaemia susceptibility locus
2010
The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression
2009
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
2012
Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability
2006
Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens
2005