Citation Impact
Citing Papers
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Microsatellite Instability, Mismatch Repair Deficiency, and BRAF Mutation in Treatment-Resistant Germ Cell Tumors
2009
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
2017
Microenvironmental regulation of tumour angiogenesis
2017
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Oxygen availability and metabolic reprogramming in cancer
2017
Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades
2019
Gonadoblastoma and selected other aspects of gonadal pathology in young patients with disorders of sex development
2014
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Roles of RUNX in Hypoxia-Induced Responses and Angiogenesis
2017
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling
2016
Complete androgen insensitivity syndrome: factors influencing gonadal histology including germ cell pathology
2013
Spinal-cord injury
2002 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
2014
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
The biology and function of fibroblasts in cancer
2016 Standout
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
2016 StandoutNobel
Oxygen availability and metabolic adaptations
2016
Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use
2014
Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets
2014
Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways
2014 StandoutNobel
Bowel dysfunction in spinal-cord-injury patients
1996
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
2007 Standout
Catecholamine-induced stimulation of growth in Vibrio species
2007
Molecular mechanisms of cisplatin resistance
2011 Standout
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Effect of a tricyclic antidepressant on small intestinal motility in health and diarrhea-predominant irritable bowel syndrome
1995
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Pharmacological targeting of the HIF hydroxylases – A new field in medicine development
2016 StandoutNobel
Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach
2002
Testicular germ-cell tumours in a broader perspective
2005 Standout
Cyclin D as a therapeutic target in cancer
2011
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Interfering with pH regulation in tumours as a therapeutic strategy
2011
Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model
2014
Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including Acetazolamide in human Glioblastoma
2013
Tumour acidosis: from the passenger to the driver's seat
2017
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival
2016
Oxidative Stress in Cancer
2020 Standout
Proline metabolism and cancer
2014
Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
2020
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Modulation of Pathogenicity with Norepinephrine Related to the Type III Secretion System ofVibrio parahaemolyticus
2007
A census of amplified and overexpressed human cancer genes
2009
The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours
2016 Standout
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
2010 Standout
Medical Treatment of Advanced Testicular Cancer
2008
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β
2018
Clonal evolution in cancer
2012 StandoutNature
The Warburg Effect: How Does it Benefit Cancer Cells?
2016 Standout
Reading, writing and erasing mRNA methylation
2019 Standout
AGA technical review on irritable bowel syndrome
2002 Standout
Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: An approach to identify candidate genes involved in tumor development
2009
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Influence of antidepressants on whole gut and orocaecal transit times in health and irritable bowel syndrome
1994
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
2014
Advances in Hypoxia-Inducible Factor Biology
2017
5-Hydroxytryptamine and human small intestinal motility: effect of inhibiting 5-hydroxytryptamine reuptake.
1994
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Serine Synthesis Helps Hypoxic Cancer Stem Cells Regulate Redox
2016 StandoutNobel
Gut Microbiota in Health and Disease
2010 Standout
Phase 2 trial of the cyclin‐dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein‐expressing germ cell tumors
2014
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Pharmacological interventions for somatoform disorders in adults
2014 Standout
Oxygen-Self-Produced Nanoplatform for Relieving Hypoxia and Breaking Resistance to Sonodynamic Treatment of Pancreatic Cancer
2017
Pediatric germ cell tumors presenting beyond childhood?
2014
Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors
2009
Combination therapy in combating cancer
2017 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors
2015
KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
2005
Works of Alan McIntyre being referenced
Genomic and Expression Profiling of Human Spermatocytic Seminomas: Primary Spermatocyte as Tumorigenic Precursor and DMRT1 as Candidate Chromosome 9 Gene
2006
Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer
2019
Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis In Vivo and Inhibition Enhances Anti-VEGF Therapy
2012
Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth
2016
Metabolic and hypoxic adaptation to anti‐angiogenic therapy: a target for induced essentiality
2015
The tumour hypoxia induced non-coding transcriptome
2016
Activating Mutations and/or Expression Levels of Tyrosine Kinase Receptors GRB7, RAS, and BRAF in Testicular Germ Cell Tumors
2005
Modulation of human upper intestinal nutrient transit by a beta adrenoreceptor mediated pathway.
1992
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation
2011
The effect of alpha‐1‐adrenoreceptor agonist and antagonist administration on kumun upper gastrointestinal transit and motility
1992
Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia
2016
Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours
2014
Stem cell factor as a novel diagnostic marker for early malignant germ cells
2008
Review article: adrenergic control of motor and secretory function in the gastrointestinal tract
1992
The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer
2016
Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells
2014
Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells
2012
The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers
2010
Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones
2004
Amplification and Overexpression of the KIT Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults
2005
Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition
2015