Standout Papers
Citation Impact
Citing Papers
Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)
1992
In vitro transport of a fluorescent nuclear protein and exclusion of non-nuclear proteins.
1986
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus
1989
Defective acidification of intracellular organelles in cystic fibrosis
1991 Nature
Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation
1991 Nature
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
1988 Standout
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Nuclear targeting sequences — a consensus?
1991 Standout
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
How proteins enter the nucleus
1991
Generation and characterization of a ΔF508 cystic fibrosis mouse model
1995 StandoutNobel
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T
1990
ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes
1997
An N-Terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110 and a second cellular protein, p120
1989
Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import
1991
Chloride channels, Golgi pH and cystic fibrosis
1992
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Distinct functions for the two importin subunits in nuclear protein import
1995 Nature
Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis
1991
In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium
1992
Identification of specific binding proteins for a nuclear location sequence
1989 Nature
Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR
1992 Nature
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
1998 StandoutNatureNobel
Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope
1995
Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation
1988
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
1989
Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src
1991 Nature
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors
1992 StandoutNobel
Nucleoside triphosphates are required to open the CFTR chloride channel
1991
Constitutive activation of Src family kinases in mouse embryos that lack Csk
1993
Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing
1988
Cellular targets for transformation by the adenovirus E1A proteins
1989
Production of a severe cystic fibrosis mutation in mice by gene targeting
1993 StandoutNobel
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product
1988 StandoutNature
Differential effects of tamoxifen and I? on three distinguishable chloride currents activated in T84 intestinal cells
1993
Facilitated nuclear transport of histone H1 and other small nucleophilic proteins
1990
Inactivation of the murine cftr gene abolishes cAMP-mediated but not Ca2+-mediated secretagogue-induced volume decrease in small-intestinal crypts
1993 StandoutNobel
Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms
1997 Nature
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase
1989 StandoutNobel
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
1988 StandoutNature
Nuclear transport of adenovirus DNA polymerase is facilitated by interaction with preterminal protein
1988
Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import
1991
Salmonella typhi uses CFTR to enter intestinal epithelial cells
1998 StandoutNatureNobel
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung afterin vivointratracheal plasmid-mediated gene transfer
1992
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
The NUP1 gene encodes an essential component of the yeast nuclear pore complex
1990
In vivo cell-specific expression of the cystic fibrosis transmembrane conductance regulator
1991 Nature
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
A mutation in the cystic fibrosis transmembrane conductance regulator gene associated with elevated sweat chloride concentrations in the absence of cystic fibrosis
1998
Localization of the cystic fibrosis transmembrane conductance regulator in pancreas.
1991
The Two Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Have Distinct Functions in Controlling Channel Activity
1995
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
1995 StandoutNobel
The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal
1990
Major nucleolar proteins shuttle between nucleus and cytoplasm
1989
CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship
1993 Nature
Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids
1996
Activation of ion transport pathways by changes in cell volume
1991
Loss of CFTR Chloride Channels Alters Salt Absorption by Cystic Fibrosis Airway Epithelia In Vitro
1998
Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells
1987
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
Molecular chaperones in cellular protein folding
1996 StandoutNature
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
1991
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
1996 StandoutNobel
Membrane conductance and cell volume changes evoked by vasoactive intestinal polypeptide and carbachol in small intestinal crypts
1992
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance
1991
Cystic fibrosis in the mouse by targeted insertional mutagenesis
1992 Nature
CFTR: Development of high- affinity antibodies and localization in sweat gland
1991
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
1989
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid
1996
Kinetic Characterization of the Human Retinoblastoma Protein Bipartite Nuclear Localization Sequence (NLS) in Vivo andin Vitro
1997
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene
1991 Nature
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family
1989
Nuclear export of proteins: The role of nuclear retention
1993
Nuclear protein localization
1991
Mechanisms of Signal Transduction to the Cell Nucleus
1990
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
The Cystic Fibrosis Transmembrane Conductance Regulator Gene
1995
Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.
1987
Regulation of Translation by Poliovirus
1987
A protein recognized by antibodies to Asp-Asp-Asp-Glu-Asp shows specific binding activity to heterogeneous nuclear transport signals.
1990
A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus.
1996
Low Level of Cellular Protein Phosphorylation by Nontransforming Overproduced p60c-src
1985
Heat-stable inhibitors of cAMP-dependent protein kinase carry a nuclear export signal.
1994 StandoutNobel
Monoclonal antibody specific for human nuclear proteins IEF 8Z30 and 8Z31 accumulates in the nucleus a few hours after cytoplasmic microinjection of cells expressing these proteins.
1986
T antigen is bound to a host protein in SY40-transformed cells
1979 StandoutNature
Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy.
1989
Chloride secretory response to extracellular ATP in human normal and cystic fibrosis nasal epithelia
1992
Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis
1986 StandoutScience
Regulation of Plasma Membrane Recycling by CFTR
1992 Science
Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain
1987
Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA
1980
Structure and Function of the Nuclear Pore Complex
1992
Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes
1991 Science
Translation of Reovirus Messenger RNAs Synthesized In Vitro into Reovirus Polypeptides by Several Mammalian Cell-Free Extracts
1972
cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.
1986 StandoutNobel
Characterization of the Polypeptides Formed in Response to Encephalomyocarditis Virus Ribonucleic Acid in a Cell-Free System from Mouse Ascites Tumor Cells
1972
Translation of Encephalomyocarditis Viral RNA in Oocytes of Xenopus laevis
1972 StandoutNobel
Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.
1994
Size and Genetic Content of Viral RNAs in Avian Oncovirus-Infected Cells
1977
At least 104 nucleotides are transposed from the 5′ terminus of the avian sarcoma virus genome to the 5′ termini of smaller viral mrnas
1978 StandoutNobel
Altered phosphorylation and activation of PP60c-src during fibroblast mitosis
1988
Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides
1985
A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo.
1988
Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal
1986
Role of Mutant CFTR in Hypersusceptibility of Cystic Fibrosis Patients to Lung Infections
1996 Science
Identification of a purified complement-fixing antigen as the Epstein-Barr-virus determined nuclear antigen (EBNA) by its binding to metaphase chromosomes.
1977 StandoutNobel
Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents.
1992
Regulation of simian virus 40 gene expression in Xenopus laevis oocytes.
1985
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells.
1981
Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen.
1977
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation
1987
ATP-dependent unwinding of messenger RNA structure by eukaryotic initiation factors.
1985
p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins.
1991
Complete nucleotide sequence of SV40 DNA
1978 Nature
Expression of a chicken chromosomal ovalbumin gene injected into frog oocyte nuclei
1980 StandoutNatureNobel
Identification of a region of simian virus 40 large T antigen required for cell transformation
1990
Defective Epithelial Chloride Transport in a Gene-Targeted Mouse Model of Cystic Fibrosis
1992 StandoutScienceNobel
Sequence requirements for synthetic peptide-mediated translocation to the nucleus.
1989
Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells.
1992
Simple Method for the Isolation of Encephalomyocarditis Virus Ribonucleic Acid
1972
p60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis.
1988
Nucleocytoplasmic Transport
1996 Science
DNAs of simian virus 40 and polyoma direct the synthesis of viral tumor antigens and capsid proteins in Xenopus oocytes.
1978
Virus Protein Synthesis in Animal Cell-Free Systems: Nature of the Products Synthesized in Response to Ribonucleic Acid of Encephalomyocarditis Virus
1971
Initiation of Haemoglobin Synthesis by Methionyl-tRNA
1970 Nature
Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells
1987
Nucleotide sequence at the 5' terminus of the avian sarcoma virus genome.
1977 StandoutNobel
Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm.
1988
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytes
1985
Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein
1990
Elevated expression of pp60c-src alters a selective morphogenetic property of epithelial cells in vitro without a mitogenic effect.
1988
The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen.
1991
Gene activation in somatic nuclei after injection into amphibian oocytes.
1977 StandoutNobel
Cystic Fibrosis Gene Mutation in Two Sisters with Mild Disease and Normal Sweat Electrolyte Levels
1991
Cloning and DNA sequence of double-stranded copies of haemagglutinin genes from H2 and H3 strains elucidates antigenic shift and drift in human influenza virus
1980 Nature
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.
1990
Identification of the Human c-myc Protein Nuclear Translocation Signal
1988
Coupled transcription-translation of DNA injected into Xenopus oocytes
1977
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
1986 StandoutNature
Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.
1995
Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.
1990
The effects of variations in the number and sequence of targeting signals on nuclear uptake.
1988
The rate of polypeptide chain elongation in a cell-free system from Krebs II ascites cells
1974
Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins
1989
The Genome of Simian Virus 40
1978 Science
Association of a murine 53,000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells
1980
The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen.
1988
Protein Synthesis Directed by Encephalomyocarditis Virus RNA: Properties of a Transfer RNA-Dependent System
1971
Identification of simian virus 40 tumor and U antigens.
1977
A nuclear localization signal binding protein in the nucleolus.
1990 StandoutNobel
Mammalian Cell‐Free Protein Synthesis Directed by Viral Ribonucleic Acid
1970
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles
1983
Interaction of a nuclear location signal with isolated nuclear envelopes and identification of signal-binding proteins by photoaffinity labeling.
1989
The Cellular src Gene Product Regulates Junctional Cell-to-Cell Communication
1988 Science
The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression.
1992
Microinjected U snRNAs are imported to oocyte nuclei via the nuclear pore complex by three distinguishable targeting pathways.
1992
Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene.
1991
Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function
1990
Prediction of similar transforming regions in simian virus 40 large T, adenovirus E1A, and myc oncoproteins
1988
A joint product of the genes gag and pol of Avian Sarcoma Virus: a possible precursor of reverse transcriptase
1977 StandoutNobel
Synthetic peptides as nuclear localization signals
1986 StandoutNatureNobel
A leader peptide is sufficient to direct mitochondrial import of a chimeric protein.
1985
Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts.
1994
Nuclear localization signals also mediate the outward movement of proteins from the nucleus.
1994
Identification and characterization of a nuclear localization sequence-binding protein in yeast.
1989
A mutant affecting the heavy chain of myosin in Caenorhabditis elegans
1974 StandoutNobel
Identification of a human protein that interacts with nuclear localization signals.
1989
Synthesis of heat-shock proteins in HeLa cells: Inhibition by virus infection
1984
Karyophilic peptides: Applications to the study of nuclear transport
1988
An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore.
1990
Potential of preventing Pseudomonas aeruginosa lung infections in cystic fibrosis patients: Experimental studies in animals
1996
Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily.
1991
Tumor antigen(s) in cells productively infected by wild-type polyoma virus and mutant NG-18
1978
Complete translation of poliovirus RNA in a eukaryotic cell-free system.
1975 StandoutNobel
CFTR protein expression in primary and cultured epithelia.
1992
Expression of simian virus 40 early genes in transformed rat cells is correlated with maintenance of the transformed phenotype
1978
Cell-free translation of avian sarcoma virus RNA: Suppression of the gag termination codon does not augment synthesis of the joint gag/pol Product
1978 StandoutNobel
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
1981 StandoutNature
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product.
1990 StandoutNobel
Association of adenovirus early-region 1A proteins with cellular polypeptides.
1986
Spliced early mRNAs of simian virus 40
1978
Effect of Pactamycin on Synthesis of Poliovirus Proteins: a Method for Genetic Mapping
1971 StandoutNobel
The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses
1977 StandoutNobel
Protein synthesis directed by encephalomyocarditis virus RNA II. The in vitro synthesis of high molecular weight proteins and elements of the viral capsid
1971
Mechanisms for the incorporation of proteins in membranes and organelles.
1982
Monoclonal antibodies specific for simian virus 40 tumor antigens
1981
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein
1978 StandoutNobel
Cystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lung
1997
Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation
1984
Nuclear transport kinetics depend on phosphorylation-site-containing sequences flanking the karyophilic signal of the Simian virus 40 T-antigen.
1989
A yeast protein that binds nuclear localization signals: purification localization, and antibody inhibition of binding activity.
1991
Nucleocytoplasmic shuttling of the progesterone receptor.
1991
Structure of the neuraminidase gene in human influenza virus A/PR/8/34
1981 StandoutNatureNobel
Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.
1987
Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein.
1990
Csk suppression of Src involves movement of Csk to sites of Src activity.
1994
The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence.
1996 StandoutNobel
Sequestration and Turnover of Guinea-Pig Milk Proteins and Chicken Ovalbumin in Xenopus Oocytes
1979
Protein Import into the Cell Nucleus
1986
Further studies on the translation of globin mRNA and encephalomyocarditis virus RNA in a cell-free system from Krebs II ascites cells
1972
Cystic Fibrosis Heterozygote Resistance to Cholera Toxin in the Cystic Fibrosis Mouse Model
1994 Science
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum
1987 StandoutNobel
Identification of the human c-myc protein nuclear translocation signal.
1988
Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line.
1992
Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells
1982
Multiple pathways in nuclear transport: the import of U2 snRNP occurs by a novel kinetic pathway.
1991
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
1988 StandoutNobel
Regulation of Cl- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP.
1992
The smallest genome RNA segment of influenza virus contains two genes that may overlap.
1979
Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny.
1982
Yeast proteins that recognize nuclear localization sequences.
1989
ABC Transporters: From Microorganisms to Man
1992 Standout
Quantitation of a 55K cellular protein: similar amount and instability in normal and malignant mouse cells.
1982
Immunocytochemical localization of the cystic fibrosis gene product CFTR.
1991
The Synthesis of Encephalomyocarditis Virus Polypeptides in Infected L-Cells and Cell-Free Systems
1974
The Inhibitory Action of a Mammalian Viral RNA on the Initiation of Protein Synthesis in a Reticulocyte Cell‐Free System
1970
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
1998 StandoutNobel
Aerosol gene delivery in vivo.
1992
Impaired cell volume regulation in intestinal crypt epithelia of cystic fibrosis mice.
1995 StandoutNobel
Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose
1972 Standout
[66] Translation of reovirus mRNA, poliovirus RNA, and bacteriophage Qβ RNA in cell-free extracts of mammalian cells
1974 StandoutNobel
In Vitro Translation of Cardiovirus Ribonucleic Acid by Mammalian Cell-free Extracts
1972
Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
2000 StandoutNobel
Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia.
1991
Alternate pathways for chloride conductance activation in normal and cystic fibrosis airway epithelial cells
1992
Genetic determination of exocrine pancreatic function in cystic fibrosis.
1992
Synthesis of α and β Chains of Rabbit Hemoglobin in a Cell-Free Extract from Krebs II Ascites Cells
1971
An Essential Signaling Role for the m 3 G Cap in the Transport of U1 snRNP to the Nucleus
1990 Science
Identification of four nuclear transport signal-binding proteins that interact with diverse transport signals.
1989
Complex splicing patterns of RNAs from the early regions of adenovirus-2
1979
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.
1985
Identification of a transformation-specific protein induced by a rous sarcoma virus
1978
New region of the simian virus 40 genome required for efficient viral transformation.
1978 StandoutNobel
Identification of a nuclear localization signal of a yeast ribosomal protein.
1985
Amino acid sequences that determine the nuclear localization of yeast histone 2B.
1987
The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs.
1991
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.
1988
Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75
1980 Nature
Production and characterisation of monoclonal and polyclonal antibodies to different regions of the cystic fibrosis transmembrane conductance regulator (cftr): Detection of immunologically related proteins
1995
Synthesis of ribosomes in Saccharomyces cerevisiae
1989
Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.
1988
cAMP-inducible chloride conductance in mouse fibroblast lines stably expressing the human cystic fibrosis transmembrane conductance regulator.
1991
An immunochemical investigation of SV40 T antigens 1. Production properties and specificity of a rabbit antibody to purified simian virus 40 large-T antigen
1978
Works of Alan E. Smith being referenced
The nuclear location signal
1985
Purification and Characterization of Recombinant Cystic Fibrosis Transmembrane Conductance Regulator from Chinese Hamster Ovary and Insect Cells
1995
Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia.
1992
Cystic Fibrosis
1995
Expression and characterization of the cystic fibrosis transmembrane conductance regulator
1990 Nature
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
1991
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
1992 Nature
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel.
1991
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
1993
Correction of cAMP-Stimulated Fluid Secretion in Cystic Fibrosis Airway Epithelia: Efficiency of Adenovirus-Mediated Gene Transfer In Vitro
1994
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
1993
Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties
1993 Nature
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis
1990 Standout
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells
1990 Nature
Intracellular protein trafficking defects in human disease
1992
Cystic fibrosis transmembrane conductance regulator: A chloride channel with novel regulation
1992
Polyoma virus transforming protein associates with the product of the c-src cellular gene
1983 Nature
Translation of RNA from Encephalomyocarditis Virus in a Mammalian Cell-free System
1970 Nature
Maturation and Function of Cystic Fibrosis Transmembrane Conductance Regulator Variants Bearing Mutations in Putative Nucleotide-Binding Domains 1 and 2
1991
Influenza virus haemagglutinin signal sequence
1979
The size of Rous sarcoma virus mRNAs active in cell-free translation
1977 Nature
Generation of cAMP-Activated Chloride Currents by Expression of CFTR
1991 Science
In vitro synthesis, glycosylation, and membrane insertion of influenza virus haemagglutinin
1979
Cell-free translation of virion RNA from nondefective and transformation-defective Rous sarcoma viruses
1976
Initiation of translation directed by 42S and 26S RNAs from Semliki Forest virus in vitro.
1976
Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity
1991 Science
The complex of polyoma virus middle-T antigen and pp60c-src.
1984
The effect of protein context on nuclear location signal function
1987
Initiator Codons in Eukaryotes
1970 Nature
Structural elements that regulate pp59c-fyn catalytic activity, transforming potential, and ability to associate with polyomavirus middle-T antigen
1991
Sodium ions and the shut-off of host cell protein synthesis by picornaviruses
1976 Nature
Protein kinase activity associated with polyoma virus middle T antigen in vitro
1979
Signal-Dependent Translocation of Simian Virus 40 Large-T Antigen into Rat Liver Nuclei in a Cell-Free System
1987
Organization and expression of early genes of simian virus 40
1978 StandoutNobel
Extensive mutagenesis of the nuclear location signal of simian virus 40 large-T antigen.
1986
Location of the sequences coding for capsid proteins VP1 and VP2 on polyoma virus DNA
1976
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
1993
Cytoplasmic Methionine Transfer RNAs from Eukaryotes
1970 Nature
Cyclic AMP-dependent protein kinase activation of cystic fibrosis transmembrane conductance regulator chloride channels in planar lipid bilayers.
1992
Specificity in Initiation of Protein Synthesis in a Fractionated Mammalian Cell-free System
1973
Simian virus 40 origin DNA-binding domain on large T antigen
1986
Stoichiometry of recombinant cystic fibrosis transmembrane conductance regulator in epithelial cells and its functional reconstitution into cells in vitro.
1994
A short amino acid sequence able to specify nuclear location
1984 Standout
Initiation and processing in vitro of the primary translation products of guinea-pig caseins
1979
Large and small tumor antigens from simian virus 40 have identical amino termini mapping at 0.65 map units.
1978
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src
1987
The abnormal location of cytoplasmic SV40 large T is not caused by failure to bind to DNA or to p53.
1985
Monomer molecular weight of T antigen from simian virus 40-infected and transformed cells.
1976
In vitro mutagenesis of a putative DNA binding domain of SV40 large-T
1984
Nuclear location signals in polyoma virus large-T
1986
Extensive Mutagenesis of the Nuclear Location Signal of Simian Virus 40 Large-T Antigen
1986
Molecular characterization of replication-competent variants of adenovirus vectors and genome modifications to prevent their occurrence
1996
Biosynthesis of 35S-l-methionine of very high specific activity
1972
Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2.
1991
Molecular biology of animal virus infection
1980
Polyoma virus high molecular weight nuclear rna codes for capsid protein VP2 in vitro
1978
Effect of Deleting the R Domain on CFTR-Generated Chloride Channels
1991 Science
Characterization of different tumor antigens present in cells transformed by simian virus 40
1979
Cell-free synthesis of simian virus 40 T-antigens
1978
Signal-dependent translocation of simian virus 40 large-T antigen into rat liver nuclei in a cell-free system.
1987
The Initiation of Protein Synthesis Directed by the RNA from Encephalomyocarditis Virus
1973
Sequence requirements for nuclear location of simian virus 40 large-T antigen
1984 Nature