Citation Impact
Citing Papers
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
2014
TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
2015 Science
Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events
2011
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
2012
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
2012
A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
2013
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
13 reasons why the brain is susceptible to oxidative stress
2018
Investigation of associations between Piezo1 mechanoreceptor gain-of-function variants and glaucoma-related phenotypes in humans and mice
2020 StandoutNobel
The Role of Autophagy in Parkinson's Disease
2012
Parkinson disease
2017 Standout
PINK1 is degraded through the N-end rule pathway
2013
Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration
2015
TREM2 in Neurodegenerative Diseases
2017
Neuropathology underlying clinical variability in patients with synucleinopathies
2011
Quality Control of Mitochondrial Proteostasis
2011
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
The role of autophagy in neurodegenerative disease
2013 Standout
Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis
2016
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
FUS(1-359) transgenic mice as a model of ALS: pathophysiological and molecular aspects of the proteinopathy
2018
C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD
2016
Parkin and mitochondrial quality control: toward assembling the puzzle
2014
ALS mutations in TLS/FUS disrupt target gene expression
2015
Microglial cell origin and phenotypes in health and disease
2011 Standout
TRAP1 rescues PINK1 loss-of-function phenotypes
2013
Amyotrophic lateral sclerosis
2017
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
The genetics and neuropathology of Parkinson’s disease
2012
Clinical utility of polygenic risk scores for coronary artery disease
2021
PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix
2014
Hexokinase activity is required for recruitment of parkin to depolarized mitochondria
2013
100 years of Lewy pathology
2012
Mitochondria: In Sickness and in Health
2012 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
2012
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Identification of miRNAs as Potential Biomarkers in Cerebrospinal Fluid from Amyotrophic Lateral Sclerosis Patients
2016
PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
2011
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
2015
The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization
2018
Multimodal biomedical AI
2022 Standout
Parkinson's disease
2015 Standout
Widespread Translational Remodeling during Human Neuronal Differentiation
2017 StandoutNobel
Profilin 1 Associates with Stress Granules and ALS-Linked Mutations Alter Stress Granule Dynamics
2014
Deciphering the Molecular Signals of PINK1/Parkin Mitophagy
2016
Autophagy in Human Health and Disease
2013 Standout
MicroRNA Expression and Regulation in Human, Chimpanzee, and Macaque Brains
2011 StandoutNobel
PINK1/Parkin-mediated mitophagy in mammalian cells
2015
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson’s disease
2013
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Protein Phase Separation: A New Phase in Cell Biology
2018
Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism
2012 Nobel
A multi-modal parcellation of human cerebral cortex
2016 StandoutNature
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
Fluorescence nanoscopy in cell biology
2017 StandoutNobel
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Dose-ranging study of riluzole in amyotrophic lateral sclerosis
1996 Standout
ICA-based artefact removal and accelerated fMRI acquisition for improved resting state network imaging
2014
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
2012
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Mitochondria: The Next (Neurode)Generation
2011
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
Physiological Roles of Mitochondrial Reactive Oxygen Species
2012 Standout
Mitonuclear communication in homeostasis and stress
2016
The PI3K Pathway in Human Disease
2017 Standout
Epidemiology of mutations in superoxide dismutase in amyotrophic lateal sclerosis
1997 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Risk factors for amyotrophic lateral sclerosis
2015
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Oxidative Stress and Altered Mitochondrial Function in Neurodegenerative Diseases: Lessons From Mouse Models
2010
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Mitochondrial quality control: a matter of life and death for neurons
2012
Brain-Specific Knock-Out of Hypoxia-Inducible Factor-1α Reduces Rather Than Increases Hypoxic-Ischemic Damage
2005
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
2011
Mitochondrial Quality Control and Dynamics in Parkinson's Disease
2011
Phase to Phase with TDP-43
2017
The Physiological Role of Mitophagy: New Insights into Phosphorylation Events
2012
Adeno‐associated virus–delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model
2016
PINK1- and Parkin-mediated mitophagy at a glance
2012
Genetics of glaucoma
2017
Functional genomics approach to hypoxia signaling
2004
Organellophagy: Eliminating cellular building blocks via selective autophagy
2014
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
2011
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
Enhanced Bone Regeneration Associated With Decreased Apoptosis in Mice With Partial HIF-1α Deficiency
2006 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
F‐domain valency determines outcome of signaling through the angiopoietin pathway
2021 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Shuttling of PINK1 between Mitochondrial Microcompartments Resolved by Triple-Color Superresolution Microscopy
2015
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
2013
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
2012
HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
2010 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
Determinants and Functions of Mitochondrial Behavior
2014
Genes associated with Parkinson's disease: regulation of autophagy and beyond
2015
Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models
2018
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Alan E. Renton being referenced
Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population
2021
Differential DJ-1 gene expression in Parkinson's disease
2009
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
2008
GroupICA dual regression analysis of resting state networks in a behavioral variant of frontotemporal dementia
2013
Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion
2014
Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy
2009
PINK1 cleavage at position A103 by the mitochondrial protease PARL
2010
State of play in amyotrophic lateral sclerosis genetics
2013
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients
2012
Hypoxia induces p53 through a pathway distinct from most DNA-damaging and stress-inducing agents
2003
OPTN 691_692insAG is a founder mutation causing recessive ALS and increased risk in heterozygotes
2016