Citation Impact
Citing Papers
Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer
2003 Standout
Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World
2006 Standout
Sym004: A Novel Synergistic Anti–Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
2010
Reconstitution of Human Telomerase Reverse Transcriptase Expression Rescues Colorectal Carcinoma Cells from In vitro Senescence: Evidence against Immortality as a Constitutive Trait of Tumor Cells
2005
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Untangling the ErbB signalling network
2001 Standout
EGFR Antagonists in Cancer Treatment
2008 Standout
Mechanism of activation of the TGF-β receptor
1994 StandoutNature
Expression of transforming growth factor-alpha in primary human colon and lung carcinomas
1990
Growth Dominance of the Metastatic Cancer Cell: Cellular and Molecular Aspects
1990
Proliferation of human colon cancer cells: Role of epidermal growth factor and transforming growth factorα
1992
Sensitivity of nuclear c-myc levels and induction to differentiation-inducing agents in human colon tumor cell lines
1992
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Role of Transforming Growth Factor β in Human Disease
2000 Standout
Growth factor requirements of human colorectal tumour cells: Relations to cellular differentiation
1991
Expression of transforming growth factor α antisense mRNA inhibits the estrogen‐induced production of TGFα and estrogen‐induced proliferation of estrogen‐responsive human breast cancer cells
1993
Different epidermal growth factor growth responses and receptor levels in human colon carcinoma cell lines
1988
A meta‐analysis of the association of physical activity with reduced risk of colorectal cancer
2005
Epidermal growth factor-related peptides and their receptors in human malignancies
1995 Standout
A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1
1999 Standout
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Dissemination and growth of cancer cells in metastatic sites
2002 Standout
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
Physical activity, obesity, and risk of colorectal adenoma in women (United States)
1996
Epithelial-mesenchymal transformation of a newly established cell line from ovarian adenosarcoma by transforming growth factor-Β1
1996
Decreased type II/type I TGF-beta receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-beta1.
1995
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium.
1990
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.
1997
DrugBank: a knowledgebase for drugs, drug actions and drug targets
2007 Standout
Tumor suppressor genes
1991 Standout
Transforming growth factor β1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells
1999
Demonstration That Mutation of the Type II Transforming Growth Factor β Receptor Inactivates Its Tumor Suppressor Activity in Replication Error-positive Colon Carcinoma Cells
1995
Erlotinib in Previously Treated Non–Small-Cell Lung Cancer
2005 Standout
Serum C-Peptide, Insulin-Like Growth Factor (IGF)-I, IGF-Binding Proteins, and Colorectal Cancer Risk in Women
2000
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Transforming Growth Factor β Activation of p44mapk in Proliferating Cultures of Epithelial Cells
1995
Paracrine growth regulation of human colon carcinoma organ-specific metastasis
1993
Epithelial–mesenchymal transitions in tumour progression
2002 Standout
Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells.
1989
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
2004 Standout
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
TGF-β receptor signaling
1997
The cell biology of transforming growth factor β
1990
Production of epidermal growth factor and transforming growth factor‐α by the androgen‐responsive LNCaP human prostate cancer cell line
1990
Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells
1998 Standout
pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest
1994 StandoutNature
Expression of TGF‐α/EGF and TGF‐p receptors in human colon carcinoma cell lines
1989
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
2011 StandoutNobel
TGFβ in Cancer
2008 Standout
Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor α and insulin like growth factor-I
1991
Slow‐release pellets of sodium butyrate increase apoptosis in the colon of rats treated with azoxymethane, without affecting aberrant crypt foci and colonic proliferation
1998
Insulin and colon cancer
1995
AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both
2017 Standout
Intestinal Tumorigenesis in Compound Mutant Mice of both Dpc4(Smad4) and Apc Genes
1998
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
1991 Standout
Differentially expressed genes in TGF-β1 sensitive and resistant human hepatoma cells
1995
Splicing of a rare class of introns by the U12-dependent spliceosome
2005
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
1992 StandoutNature
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
The basics of epithelial-mesenchymal transition
2009 Standout
Infection with a transforming growth factor α anti‐sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line
1993
Control of Type II Transforming Growth Factor-β Receptor Expression by Integrin Ligation
1999
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Expression of Differentiation Antigens and Growth-Related Genes in Normal Kidney, Autosomal Dominant Polycystic Kidney Disease, and Renal Cell Carcinoma
1992
The role of growth regulatory aberrations in progression of human colon carcinoma
1993
Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion
1998
Wnt signalling in stem cells and cancer
2005 StandoutNature
Altered Transforming Growth Factor β Signaling in Epithelial Cells when Ras Activation Is Blocked
1996
Autonomous proliferation of colon cancer cells that coexpress transforming growth factor α and its receptor
1992
TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
1990 Standout
Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis
1991
Tumor suppressor activity of the TGF-β pathway in human cancers
1996
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.
1990
Inhibitory effects of transforming growth factor beta 1 on mitogenic response, transforming growth factor alpha, and c-myc in quiescent, well-differentiated colon carcinoma cells.
1990
Identification and biological characterization of an epidermal growth factor-related protein: cripto-1.
1994
Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.
1993
TGF-β SIGNAL TRANSDUCTION
1998 Standout
Transforming growth factors beta 1 and 2 transcriptionally regulate human papillomavirus (HPV) type 16 early gene expression in HPV-immortalized human genital epithelial cells
1990
G 1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: Phenotypes reversed by a tumorigenic mutation
1999
Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
2001 Standout
Analysis of Genomic and Proteomic Data Using Advanced Literature Mining
2003
Phenotypic characterization of human colorectal cancer stem cells
2007 Standout
Targeted deletion of Smad4 shows it is required for transforming growth factor β and activin signaling in colorectal cancer cells
1998
Estrogens, antiestrogens and cell proliferation
1989
A Dominant Inhibitory Mutant of the Type II Transforming Growth Factor β Receptor in the Malignant Progression of a Cutaneous T-Cell Lymphoma
1996
Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor
1999
Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model
1988 StandoutScience
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation
2006
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells
1994
Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells.
1994
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells.
1996
Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression.
1993
Dental Students’ Use of AMSTAR to Critically Appraise Systematic Reviews
2015
Sperm-induced local[Ca2+]i rise separated from the Ca2+ wave in sea urchin eggs in the presence of a gamete fusion inhibitor, jaspisin
1998 StandoutNobel
1997 StandoutNobel
Viruses in Human Cancers
1991 StandoutScienceNobel
Growth factor production by human colon carcinoma cell lines.
1989
Cancer Genome Landscapes
2013 StandoutScience
Up-regulation of transforming growth factor alpha expression by transforming growth factor beta 1, epidermal growth factor, and N,N-dimethylformamide in human colon carcinoma cells.
1993
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Differential regulation of the JE gene encoding the monocyte chemoattractant protein (MCP-1) in cervical carcinoma cells and derived hybrids
1994 StandoutNobel
Cell type-specific modulation of cell growth by transforming growth factor beta 1 does not correlate with mitogen-activated protein kinase activation.
1995
Differential expression of epidermal growth factor-related proteins in human colorectal tumors.
1991
Regulation of growth saturation and development of necrosis in EMT6/Ro multicellular spheroids by the glucose and oxygen supply.
1986
Autocrine transforming growth factor-alpha is associated with progression of transformed properties in human colon cancer cells.
1993
Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors.
1992
Activation of p21ras by transforming growth factor beta in epithelial cells.
1992
Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis.
1999
Inhibition of growth by transforming growth factor-beta following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses.
1992
SIGNALING PATHWAYS IN INTESTINAL DEVELOPMENT AND CANCER
2004
Transforming growth factor-beta 1 induces transforming growth factor-alpha promoter activity and transforming growth factor-alpha secretion in the human colon adenocarcinoma cell line FET.
1993
The two faces of transforming growth factor β in carcinogenesis
2003 Standout
Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm.
1987
Transforming growth factor β and cancer
1995
Works of Alan E. Levine being referenced
Sodium butyrate alters the response of a human colon carcinoma cell line to transforming growth factor-β1
1992
Modulation of C-myc by transforming growth factor-β in human colon carcinoma cells
1988
Pro‐transforming growth factor‐alpha processing in human colon carcinoma cells: Role of protein kinase C
1995
Transforming growth factor-β2 is an autocrine growth inhibitory factor for the MOSER human colon carcinoma cell line
1993
Involvement of protein kinase C and an elastase‐like enzyme in the processing of transforming growth factor‐α in human colon carcinoma cell lines
1994
Characterization of the synergistic effect of insulin and transferrin and the regulation of their receptors on a human colon carcinoma cell line
1990
Differential sensitivity of subclasses of human colon carcinoma cell lines to the growth inhibitory effects of transforming growth factor-β1
1989
OrCGDB: a database of genes involved in oral cancer
2001
Differential role of transforming growth factor‐α in two human colon‐carcinoma cell lines
1991
Digital reviews in molecular biology: approaches to structured digital publication
2000
Modulation of a high molecular weight form of transforming growth factor-α in human colon carcinoma cell lines
1988
Up-regulation of c-myc in a transformed cell line approaching stationary phase growth in culture.
1989
Heterogeneity of human colon carcinoma
1984
Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agarose.
1988
Characterization of transforming growth factor-beta-resistant subclones isolated from a transforming growth factor-beta-sensitive human colon carcinoma cell line.
1988
Identification of a tumor inhibitory factor in rat ascites fluid
1984
Development of an Interdisciplinary Course in Information Resources and Evidence‐Based Dentistry
2008
Characterization of the inhibitory effects of transforming growth factor-beta on a human colon carcinoma cell line.
1987
Involvement of an acrosin-like enzyme in the acrosome reaction of sea urchin sperm
1979