Citation Impact
Citing Papers
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
2001 StandoutScience
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis.
1996
Small GTP-Binding Proteins
1992
From molecular to modular cell biology
1999 StandoutNatureNobel
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Constitutive mutants in the yeast pheromone response: Ordered function of the gene products
1989
Synthetic enhancement in gene interaction: a genetic tool come of age
1993
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Saccharomyces cerevisiae mata mutant cells defective in pointed projection formation in response to α‐factor at high concentrations
1994 StandoutNobel
Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae.
1994
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1
1991
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
1988 StandoutNatureNobel
The DAF2-2 mutation, a dominant inhibitor of the STE4 step in the alpha-factor signaling pathway of Saccharomyces cerevisiae MAT alpha cells.
1990
Using cancer genetics to guide the selection of anticancer drug targets
2002
Cell cycle control of morphogenesis in budding yeast
1995
A regulatory hierarchy for cell specialization in yeast
1989 Nature
Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
1990 StandoutNobel
Activation of Yeast Protein Kinase C by Rho1 GTPase
1996
Rho-related proteins: actin cytoskeleton and cell cycle
1995
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
The GTPase superfamily: conserved structure and molecular mechanism
1991 StandoutNature
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae
1994 Standout
Development of cell polarity in budding yeast
1991
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization
1996
The yeast nucleoporin Rip1p contributes to multiple export pathways with no essential role for its FG-repeat region
1997 StandoutNobel
Discovering the poles in yeast
1998 StandoutNobel
Establishment of a Chemical Synthetic Lethality Screen in Cultured Human Cells
2001
A role for Rac in Tiaml-induced membrane ruffling and invasion
1995 Nature
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Rho GTPases and signaling networks
1997 Standout
Control of the yeast cell cycle by the Cdc28 protein kinase
1993
Cell polarity in yeast
1994
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
Ubiquitination of the PEST-like Endocytosis Signal of the Yeast a-Factor Receptor
2000
Genetic synthetic lethality screen at the single gene level in cultured human cells
2001
Genetic approaches to nuclear pore structure and function
1995
The Yeast Phosphatidylinositol Kinase Homolog TOR2 Activates RHO1 and RHO2 via the Exchange Factor ROM2
1997
The structure and function of the homeodomain
1989 Standout
Selection of polarized growth sites in yeast
1996
Protein modules and signalling networks
1995 StandoutNature
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
1992 StandoutNatureNobel
Origins of Cell Polarity
1996
Phermone response in yeast
1990
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
Use of isogenic human cancer cells for high-throughput screening and drug discovery
2001
Cooperative interaction of S. pombe proteins required for mating and morphogenesis
1994
GTPase cascades choreographing cellular behavior: Movement, morphogenesis, and more
1995
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
Identification of a Gl-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe
1991 StandoutNatureNobel
Pheromone signalling and polarized morphogenesis in yeast
1997
Establishment of Cell Polarity in Yeast
1995
Cell polarity and morphogenesis in Saccharomyces cerevisiae
1992
SH3 — an abundant protein domain in search of a function
1992
The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
1988 StandoutNobel
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway
1991
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae
1989
The Faciogenital Dysplasia Gene Product FGD1 Functions as a Cdc42Hs-specific Guanine-Nucleotide Exchange Factor
1996
CRYSTAL STRUCTURE OF THE SH3 DOMAIN IN HUMAN FYN; COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SH3 DOMAINS IN TYROSINE KINASES AND SPECTRIN
1993
Conjugation in Saccharomyces cerevisiae
1988 StandoutNobel
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.
1988
Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.
1991
Nucleocytoplasmic transport of macromolecules
1997
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
Pheromone Response in Yeast: Association of Bem1p with Proteins of the MAP Kinase Cascade and Actin
1995 Science
Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p.
1994
Small GTP-Binding Proteins
2001 Standout
Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p.
1995 StandoutNobel
Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast.
1996
Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.
1995 StandoutNobel
Components required for cytokinesis are important for bud site selection in yeast
1993
Bee1, a Yeast Protein with Homology to Wiscott-Aldrich Syndrome Protein, Is Critical for the Assembly of Cortical Actin Cytoskeleton
1997
Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction.
1990
High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A
1997
Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring
1996 StandoutNobel
Pheromonal Regulation and Sequence of the Saccharomyces cerevisiae SST2 Gene: A Model for Desensitization to Pheromone
1987
The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast.
1991
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Specification of sites for polarized growth in Saccharomyces cerevisiae and the influence of external factors on site selection.
1992
The yeast STE12 protein binds to the DNA sequence mediating pheromone induction.
1989
FAR1 is required for oriented polarization of yeast cells in response to mating pheromones.
1995
Secretion in yeast: structural features influencing the post-translational translocation of prepro-alpha-factor in vitro.
1987
Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast.
1995
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
An arf1Δ Synthetic Lethal Screen Identifies a New Clathrin Heavy Chain Conditional Allele That Perturbs Vacuolar Protein Transport in Saccharomyces cerevisiae
1998
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Transcriptional Regulation in the Yeast Life Cycle
1987 Science
Correction: Identification of a Gl-type cyclin puc+ in the fission yeast Schizosaccharomyces pombe
1991 StandoutNatureNobel
STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes.
1989
DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray
2003
Independent Photoreceptive Circadian Clocks Throughout Drosophila
1997 StandoutScienceNobel
DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.
1988
AFR1Promotes Polarized Apical Morphogenesis inSaccharomyces cerevisiae
1995
Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum
1993 StandoutScienceNobel
Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants.
1989
A new subclass of nucleoporins that functionally interact with nuclear pore protein NSP1.
1992
Requirement for Three Novel Protein Complexes in the Absence of the Sgs1 DNA Helicase in Saccharomyces cerevisiae
2001
Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily
1991
Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: a model for desensitization to pheromone.
1987
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.
1992
Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.
1990
Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor.
1986
Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients.
1995 StandoutNobel
Life cycle of the budding yeast Saccharomyces cerevisiae
1988
Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity
1997
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
A Synthetic Lethal Screen Identifies SLK1, a Novel Protein Kinase Homolog Implicated in Yeast Cell Morphogenesis and Cell Growth
1992
Regulation of the yeast pheromone response pathway by G protein subunits.
1990
The SH3-Domain Protein Bem1 Coordinates Mitogen-Activated Protein Kinase Cascade Activation with Cell Cycle Control in Saccharomyces cerevisiae
1996
STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast.
1990
The Cellular Functions of Small GTP-Binding Proteins
1990 Science
A resetting signal between Drosophila pacemakers synchronizes morning and evening activity
2005 StandoutNatureNobel
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction
1987
Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation.
1991
The carboxyl terminus of Scg1, the G alpha subunit involved in yeast mating, is implicated in interactions with the pheromone receptors.
1991
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.
1994
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
1993 StandoutNatureNobel
Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.
1991
Mutations in a gene encoding the alpha subunit of a Saccharomyces cerevisiae G protein indicate a role in mating pheromone signaling.
1988
Yeast Pheromone Response Pathway: Characterization of a Suppressor That Restores Mating to Receptorless Mutants
1989
RAP1 protein activates and silences transcription of mating-type genes in yeast.
1991
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
1993
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway
1987
Mutations in a Gene Encoding the α Subunit of a Saccharomyces cerevisiae G Protein Indicate a Role in Mating Pheromone Signaling
1988
Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.
1987
Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src.
1993
Identification and Regulation of a Gene Required for Cell Fusion during Mating of the Yeast Saccharomyces cerevisiae
1987
Inhibition of Adenylyl Cyclase by G iα
1993 StandoutScienceNobel
Control of Yeast Mating Signal Transduction by a Mammalian β 2 -adrenergic Receptor and G s α Subunit
1990 StandoutScienceNobel
A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.
1992
The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog.
1988
Role of Bud3p in producing the axial budding pattern of yeast.
1995
Principles for the Buffering of Genetic Variation
2001 Science
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Cell polarization directed by extracellular cues in yeast.
1994
A modular misexpression screen in Drosophila detecting tissue-specific phenotypes.
1996
Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase.
1992 StandoutNobel
BET1, BOS1, and SEC22 Are Members of a Group of Interacting Yeast Genes Required for Transport from the Endoplasmic Reticulum to the Golgi Complex
1990
Regulation of Cell Polarity by Microtubules in Fission Yeast
1998 StandoutNobel
CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.
1990
Works of Alan Bender being referenced
A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains
1992 Nature
Pheromones and pheromone receptors are the primary determinants of mating specificity in the yeast Saccharomyces cerevisiae.
1989
Interactions among Proteins Involved in Bud-site Selection and Bud-site Assembly in Saccharomyces cerevisiae
1995
Interactions between the Ankyrin Repeat-Containing Protein Akr1p and the Pheromone Response Pathway inSaccharomyces cerevisiae
1996
Genetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeast.
1993
Control of yeast alpha-specific genes: evidence for two blocks to expression in MATa/MAT alpha diploids.
1985
Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast.
1994
Identification of the Bud Emergence Gene BEM4 and Its Interactions with Rho-Type GTPases in Saccharomyces cerevisiae
1996
Yeast peptide pheromones, a-factor and α-factor, activate a common response mechanism in their target cells
1986
Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae.
1991
Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3.
1994
Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.
1993
Use of a Screen for Synthetic Lethal and Multicopy Suppressee Mutants To Identify Two New Genes Involved in Morphogenesis in Saccharomyces cerevisiae
1991
Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.
1989
Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in Yeast.
1996
MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes
1987
RSR1, a ras-Like Gene Homologous to Krev-1 (smg21A/rap1A): Role in the Development of Cell Polarity and Interactions with the Ras Pathway in Saccharomyces cerevisiae
1992