Citation Impact
Citing Papers
Renal dopamine and the tubular handling of sodium
1995
The hERG potassium channel and hERG screening for drug-induced torsades de pointes
2008
Effects of Fluorine Substitution on Drug Metabolism: Pharmacological and Toxicological Implications
1994
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Natural products: An evolving role in future drug discovery
2011 Standout
Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products
2010
Role of Endogenous Dopamine in the Natriuretic Response to Various Degrees of Iso-Osmotic Volume Expansion in Rats
1991
hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds
2011
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
<b>Methylnaltrexone Methobromide: The First Peripherally Active, Centrally Inactive Opioid Receptor-Antagonist Clinical Review</b>
2009
Opioid-induced Delay in Gastric Emptying
1997
Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
2014 Standout
Muscle on a chip: In vitro contractility assays for smooth and striated muscle
2012
Microfluidic organs-on-chips
2014 Standout
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
2009 StandoutNobel
The use of spirocyclic scaffolds in drug discovery
2014 Standout
Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure
2007
Evaluation of Drugs With Specific Organ Toxicities in Organ-Specific Cell Lines
2011
Assessing the proarrhythmic potential of drugs: Current status of models and surrogate parameters of torsades de pointes arrhythmias
2006
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
2012
An analysis of the attrition of drug candidates from four major pharmaceutical companies
2015 Standout
Magnesium in Man: Implications for Health and Disease
2014 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Test article concentrations in the hERG assay: Losses through the perfusion, solubility and stability
2008
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
2011 StandoutNobel
The renal dopamine receptors.
1992
Methylnaltrexone Mechanisms of Action and Effects on Opioid Bowel Dysfunction and Other Opioid Adverse Effects
2007
Natural product and natural product derived drugs in clinical trials
2014 Standout
Calcitonin Gene‐Related Peptide ( CGRP ) and Migraine Current Understanding and State of Development
2013
Diabetic Neuropathy: A Position Statement by the American Diabetes Association
2016 Standout
Opioid Complications and Side Effects
2008 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Dopamine Receptors: From Structure to Function
1998 Standout
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Nature Inspired Small Molecules for Chemical Biology
2018
Methylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effects
2006
Works of Alan Bass being referenced
Origins, practices and future of safety pharmacology
2004
Selective Role of Dopamine in the Natriuresis Produced by Iso-Osmotic Saline Infusion
1991
Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1)
2012
Non-clinical evaluation of ventricular repolarization (ICH S7B): Results of an interim survey of international pharmaceutical companies
2005
Dose‐Related Antagonism of the Emetic Effect of Morphine by Methylnaltrexone in Dogs
1993
Role of Endogenous Dopamine in the Natriuresis Accompanying Various Sodium Challenges
1990
Drugs effects on ventricular repolarization: A critical evaluation of the strengths and weaknesses of current methodologies and regulatory practices
2005
Exploratory drug safety: A discovery strategy to reduce attrition in development
2009
ILSI-HESI cardiovascular safety subcommittee initiative: Evaluation of three non-clinical models of QT prolongation
2006
Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics
2008
Effect of ring fluorination of epinephrine on its cardiovascular adrenoceptor activities
1990