Standout Papers
Citation Impact
Citing Papers
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses
2006
Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target
2011
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Mitochondrial double-stranded RNA triggers antiviral signalling in humans
2018 Nature
RNAi screening comes of age: improved techniques and complementary approaches
2014
The F-box protein TIR1 is an auxin receptor
2005 StandoutNature
The NEDD8 Pathway Is Essential for SCFβ-TrCP-mediated Ubiquitination and Processing of the NF-κB Precursor p105
2002 StandoutNobel
A view on drug resistance in cancer
2019 StandoutNature
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
RIG-I-like receptors: their regulation and roles in RNA sensing
2020
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2
2007
Shared Principles in NF-κB Signaling
2008 Standout
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
β-TrCP Mediates the Signal-induced Ubiquitination of IκBβ
1999
A Dominant-negative UBC12 Mutant Sequesters NEDD8 and Inhibits NEDD8 Conjugation in Vivo
2000
A selectable, plasmid-based system to generate CRISPR/Cas9 gene edited and knock-in mosquito cell lines
2021 Nobel
Three Different Binding Sites of Cks1 Are Required for p27-Ubiquitin Ligation
2002 StandoutNobel
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
2007 StandoutNature
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Selective Degradation of Host MicroRNAs by an Intergenic HCMV Noncoding RNA Accelerates Virus Production
2013
The Nuclear Ubiquitin-Proteasome System Degrades MyoD
2001 StandoutNobel
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
2018 Standout
Homodimer of Two F-box Proteins βTrCP1 or βTrCP2 Binds to IκBα for Signal-dependent Ubiquitination
2000
Missing Pieces in the NF-κB Puzzle
2002 Standout
Control of Meiotic and Mitotic Progression by the F Box Protein β-Trcp1 In Vivo
2003
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Metazoan MicroRNAs
2018 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration
2016 StandoutNobel
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase
2000 StandoutNobel
Regulatory functions of ubiquitination in the immune system
2002
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Ubiquitylation and Destruction of Endogenous c-MycS by the Proteasome: Are Myc Boxes Dispensable?
2000 StandoutNobel
Oncogenic aberrations of cullin-dependent ubiquitin ligases
2004
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Signaling to NF-κB
2004 Standout
Common Pathway for the Ubiquitination of IκBα, IκBβ, and IκBε Mediated by the F-Box Protein FWD1
1999
PKR Transduces MDA5-Dependent Signals for Type I IFN Induction
2016
Degradation of the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) by the Ubiquitin-Proteasome Pathway
2000 StandoutNobel
The NF- B Family of Transcription Factors and Its Regulation
2009 Standout
Degradation of Cellular miR-27 by a Novel, Highly Abundant Viral Transcript Is Important for Efficient Virus Replication In Vivo
2012
Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells
1999
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Molecular Biology of Rift Valley Fever Virus~!2009-11-04~!2009-11-25~!2010-04-22~!
2010
Modes of regulation of ubiquitin-mediated protein degradation
2000 StandoutNobel
Reciprocal Inhibition between Intracellular Antiviral Signaling and the RNAi Machinery in Mammalian Cells
2013
Inducible NF-κB Activation Is Permitted by Simultaneous Degradation of Nuclear IκBα
2000
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Molecular Biology of Rift Valley Fever Virus
2010
Regulation of transcription factors by protein degradation
2000
The evolution of RNAi as a defence against viruses and transposable elements
2008
Transcriptional Activation of Alpha/Beta Interferon Genes: Interference by Nonsegmented Negative-Strand RNA Viruses
2005
SCF and Cullin/RING H2-Based Ubiquitin Ligases
1999
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
ATF4 Degradation Relies on a Phosphorylation-Dependent Interaction with the SCFβTrCPUbiquitin Ligase
2001
Nedd8 Modification of Cul-1 Activates SCFβTrCP-Dependent Ubiquitination of IκBα
2000
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Introduction, Spread, and Establishment of West Nile Virus in the Americas
2019
Visualizing the Replication Cycle of Bunyamwera Orthobunyavirus Expressing Fluorescent Protein-Tagged Gc Glycoprotein
2010
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20
2018 StandoutNobel
Wortmannin-Sensitive Pathway Is Required for Insulin-Stimulated Phosphorylation of Inhibitor κBα
2002
The Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors
2002
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates
2006 StandoutScience
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 Standout
The Use of In Vitro Peptide-Library Screens in the Analysis of Phosphoserine/Threonine-Binding Domain Structure and Function
2004
Impaired degradation of inhibitory subunit of NF-κB (IκB) and β-catenin as a result of targeted disruption of the β- TrCP1 gene
2003
Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation
2006
Works of Alain Kohl being referenced
Homotypic Interaction of Bunyamwera Virus Nucleocapsid Protein
2005
Inducible Degradation of IκBα by the Proteasome Requires Interaction with the F-box Protein h-βTrCP
1999
Characterization of the Zika virus induced small RNA response in Aedes aegypti cells
2017
Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection
2016
Optineurin Negatively Regulates the Induction of IFNβ in Response to RNA Virus Infection
2010
Combined agonist–antagonist genome-wide functional screening identifies broadly active antiviral microRNAs
2010
Non-Structural Proteins of Arthropod-Borne Bunyaviruses: Roles and Functions
2013
Bunyamwera Virus Nonstructural Protein NSs Counteracts Interferon Regulatory Factor 3-Mediated Induction of Early Cell Death
2003
La Crosse Bunyavirus Nonstructural Protein NSs Serves To Suppress the Type I Interferon System of Mammalian Hosts
2007
Role of the Cytoplasmic Tail Domains of Bunyamwera Orthobunyavirus Glycoproteins Gn and Gc in Virus Assembly and Morphogenesis
2007
Requirement of the N-Terminal Region of Orthobunyavirus Nonstructural Protein NSm for Virus Assembly and Morphogenesis
2006
Antiviral RNA Interference Responses Induced by Semliki Forest Virus Infection of Mosquito Cells: Characterization, Origin, and Frequency-Dependent Functions of Virus-Derived Small Interfering RNAs
2010
Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling
2018
Noncoding Flavivirus RNA Displays RNA Interference Suppressor Activity in Insect and Mammalian Cells
2012
NSs Protein of Rift Valley Fever Virus Blocks Interferon Production by Inhibiting Host Gene Transcription
2004
PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response
2009
Fighting Arbovirus Transmission: Natural and Engineered Control of Vector Competence in Aedes Mosquitoes
2015
Aedes aegypti Piwi4 Is a Noncanonical PIWI Protein Involved in Antiviral Responses
2017