Citation Impact
Citing Papers
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
2005
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Circulating Interleukin (IL)-8, IL-2R, IL-12, and IL-15 Levels Are Independently Prognostic in Primary Myelofibrosis: A Comprehensive Cytokine Profiling Study
2011
Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA double mutant AML as a distinctive disease entity
2010
The Stability of the Ternary Interferon-Receptor Complex Rather than the Affinity to the Individual Subunits Dictates Differential Biological Activities
2008
Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
2013 StandoutNobel
Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial
2009 Standout
TPM3-ALK and TPM4-ALK Oncogenes in Inflammatory Myofibroblastic Tumors
2000 Standout
Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis
2009
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa
2001
Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells
2009 StandoutNobel
Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor
2001 Standout
RUNX1 gene mutation in primary myelodysplastic syndrome – the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome
2007
Chromatin regulation by AML1 complex
2007
Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia
2010
Crizotinib inALK-Rearranged Inflammatory Myofibroblastic Tumor
2010 Standout
Acquired resistance to tyrosine kinase inhibitors during cancer therapy
2008
Activity of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, against human FIP1L1-PDGFR-α-expressing cells
2006
Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations
2002
IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis
2010
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
c‐kit proto‐oncogene exon 8 in‐frame deletion plus insertion mutations in acute myeloid leukaemia
1999
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Cancer genes and the pathways they control
2004 Standout
Regulation of PDGF and its receptors in fibrotic diseases
2004
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
2002 StandoutNobel
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Pathogenetic mechanisms of polycythemia vera and congenital polycythemic disorders
2001
Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals
2007
Angiogenesis in life, disease and medicine
2005 StandoutNature
c‐kit Gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors
2003
KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors
2000
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Molecular genetics in acute myeloid leukemia
2010
Diabetic foot ulcers
2003 Standout
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
1990
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
Biology of Gastrointestinal Stromal Tumors:KITMutations and Beyond
2004
Autophagy and Aging
2011 Standout
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Mutations in Exons 9 and 13 of KIT Gene Are Rare Events in Gastrointestinal Stromal Tumors
2000
Somatic point mutations in RUNX1/CBFA2/AML1 are common in high‐risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia
2004
Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias
2010
Role of KIT and platelet-derived growth factor receptors as oncoproteins
2004
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Transforming Growth Factor β in Tissue Fibrosis
1994 Standout
Bone metastasis: the importance of the neighbourhood
2016
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Genetics of therapy-related myelodysplasia and acute myeloid leukemia
2008
Molecular basis for polycythemia
1999
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Glycosylation in cancer: mechanisms and clinical implications
2015 Standout
PLATELET-DERIVED GROWTH FACTOR
1989
TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
1990 Standout
PDGF AA homodimers are potent chemoattractants for fibroblasts and neutrophils, and for monocytes activated by lymphocytes or cytokines
1992
Adipocytic cells cultured from marrow have osteogenic potential
1991
Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes
2011
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development
2010 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Acute Myeloid Leukemia
2015 Standout
Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells
2002
Platelet-derived growth factor concentrations in platelet-poor plasma and urine from patients with myeloproliferative disorders
1989
Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset
2011 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Biology of Gastrointestinal Stromal Tumors
2004 Standout
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
2003 Standout
RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis
2010
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.
2001
Adhesion Receptors as Regulators of the Hematopoietic Process
1998
Normal and Oncogenic Forms of the Receptor Tyrosine Kinase Kit
2005
AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations
2009
Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo
2000 Standout
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Adult hematopoietic stem cells lacking Hif-1α self-renew normally
2016 StandoutNobel
IFN-α–Induced Apoptosis in Hepatocellular Carcinoma Involves Promyelocytic Leukemia Protein and TRAIL Independently of p53
2009
RUNX1Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group
2011
New mutations and pathogenesis of myeloproliferative neoplasms
2011
Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex.
1989
Human dendritic cell subsets in NOD/SCID mice engrafted with CD34+ hematopoietic progenitors
2003
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
2011
Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: Variations in yield, growth, and differentiation
1999
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice
2011 StandoutNobel
Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment
2011
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Plasma elevation of stromal cell–derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
2001 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Works of Akiro Kimura being referenced
Platelet Derived Growth Factor Expression, Myelofibrosis and Chronic Myelogenous Leukemia
1995
Transforming growth factor‐β regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts
1989
Platelet‐derived growth factor is decreased in patients with myeloproliferative disorders
1988
Initial expression of interferon alpha receptor 2 (IFNAR2) on CD34‐positive cells and its down‐regulation correlate with clinical response to interferon therapy in chronic myelogenous leukemia
2004
Decreased L‐selectin expression in CD34‐positive cells from patients with chronic myelocytic leukaemia
1996
Effects of platelet derived growth factor, epidermal growth factor and transforming growth factor‐β on the growth of human marrow fibroblasts
1988
Establishment of the acute myeloid leukemia cell line Kasumi‐6 from a patient with a dominant‐negative mutation in the DNA‐binding region of the C/EBPα gene
2002
A possible role for the loss of CD27–CD70 interaction in myelomagenesis
2003
Treatment with IFNαin vivo up‐regulates serum‐soluble TNF‐related apoptosis inducing ligand (sTRAIL) levels and TRAIL mRNA expressions in neutrophils in chronic myelogenous leukemia patients
2007
c‐kit point mutation of extracellular domain in patients with myeloproliferative disorders
1995
c-Kit Point mutation in patients with myeloproliferative disorders
1997
Establishment and characterization of a novel imatinib‐sensitive chronic myeloid leukemia cell line MYL, and an imatinib‐resistant subline MYL‐R showing overexpression of Lyn
2007
Acute Myelogenous Leukemia WithPIG-A Gene Mutation Evolved from Aplastic Anemia—Paroxysmal Nocturnal Hemoglobinuria Syndrome
2001
Platelet derived growth factor messenger RNA is increased in bone marrow megakaryocytes in patients with myeloproliferative disorders
1990
Platelet‐derived growth factor expression in accelerated and blastic phase of chronic myelogenous leukaemia with myelofibrosis
1994
High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia
2003
Pyridoxine Refractory X-Linked Sideroblastic Anemia Caused by a Point Mutation in the Erythroid 5-Aminolevulinate Synthase Gene
1997
Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia
2002
Pyridoxine Refractory X-Linked Sideroblastic Anemia Caused by a Point Mutation in the Erythroid 5-Aminolevulinate Synthase Gene
1997
AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasms
2009
Arrest of human dendritic cells at the CD34−/CD4+/HLA-DR+ stage in the bone marrow of NOD/SCID-human chimeric mice
2001
[20] Platelet α-granule protein-induced chemotaxis of inflammatory cells and fibroblasts
1989
Osteoprogenitor differentiation is not affected by immunomodulatory thalidomide analogs but is promoted by low bortezomib concentration, while both agents suppress osteoclast differentiation
2008