Citation Impact
Citing Papers
Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Biological Mechanism Profiling Using an Annotated Compound Library
2003
Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: Determination of efficacy and possible mechanisms of resistance
2002
A temporary stereocentre approach for the asymmetric synthesis of chiral cyclopropane-carboxaldehydes
2009
Erlotinib Plus Gemcitabine Compared With Gemcitabine Alone in Patients With Advanced Pancreatic Cancer: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group
2007 Standout
Recent progress in the chemistry of the monoterpenoid indole alkaloids
1995
Pancreatic cancer
2004 Standout
Ferroptosis: Death by Lipid Peroxidation
2015 Standout
Chemistry and biology of monoterpene indole alkaloid biosynthesis
2006 Standout
The biological action of saponins in animal systems: a review
2002 Standout
Organocatalytic cascade reactions as a new tool in total synthesis
2010 Standout
Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
2012 StandoutNobel
Plants as a source of anti-cancer agents
2005 Standout
Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists
2005
Synthesis of Biomolecule‐Modified Mesoporous Silica Nanoparticles for Targeted Hydrophobic Drug Delivery to Cancer Cells
2011 StandoutNobel
DE‐310, a novel macromolecular carrier system for the camptothecin analog DX‐8951f: Potent antitumor activities in various murine tumor models
2004
Branched-chain fatty acid requirement for avermectin production by a mutant of Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity.
1991
Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents
1997
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
2013 Standout
Marine natural products
1990 Standout
Immunoconjugates and long circulating systems: Origins, current state of the art and future directions
2012
Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs
2002
Induction of apoptosis in estrogen dependent and independent breast cancer cells by the marine terpenoid dehydrothyrsiferol
2003
Stepwise aromatic nucleophilic substitution in continuous flow. Synthesis of an unsymmetrically substituted 3,5-diamino-benzonitrile library
2010
Recent developments in biochemistry of the plant lipoxygenase pathway
1998
Visible light photocatalysis as a greener approach to photochemical synthesis
2010 Standout
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
2010 StandoutNobel
The complex microbiota of raw milk
2013 Standout
Medicinal plants: Traditions of yesterday and drugs of tomorrow
2005 Standout
Polymer conjugates as anticancer nanomedicines
2006 Standout
Targeting multidrug resistance in cancer
2006 Standout
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads
2016
Camptothecin and its analogues: a review on their chemotherapeutic potential
2005
DX‐8951f: Summary of Phase I Clinical Trials
2000
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
Asymmetric Total Synthesis of Solandelactone E: Stereocontrolled Synthesis of the 2‐ene‐1,4‐diol Core through a Lithiation–Borylation–Allylation Sequence
2010
Gimatecan, a novel camptothecin with a promising preclinical profile
2004
Camptothecin and Its Analogs
1996
Natural products to drugs: natural product derived compounds in clinical trials
2005
Camptothecin: current perspectives
2004
Biological activities and distribution of plant saponins
2004 Standout
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Natural products in drug discovery
2008 Standout
DJ‐927, a novel oral taxane, overcomes P‐glycoprotein‐mediated multidrug resistance in vitro and in vivo
2003
Camptothecins
2002
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
2003
Carbohydrate–steroid conjugation by Ugi reaction: one-pot synthesis of triple sugar/pseudo-peptide/spirostane hybrids
2012
Regulation of bovine kidney branched-chain 2-oxoacid dehydrogenase complex by reversible phosphorylation
1984 StandoutNobel
Stereoselective Synthesis and Antifungal Activities of (E)-α-(Methoxyimino)benzeneacetate Derivatives Containing 1,3,5-Substituted Pyrazole Ring
2006
A short and efficient general synthesis of luotonin A, B and E
2004
Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions
2011 Standout
Discovery and development of antimitotic agents that inhibit tubulin polymerisation for the treatment of cancer
2002
Antitubulin agents for the treatment of cancer – a medicinal chemistry update
2006
The chemistry of recently isolated naturally occurring quinazolinone alkaloids
2006 Standout
AGROACTIVE COMPOUNDS OF MICROBIAL ORIGIN
1993 StandoutNobel
Antioxidative Properties of Phenolic Antioxidants Isolated from Corn Steep Liquor
2000
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects – A review
2015 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Homocamptothecin, an E-Ring-Modified Camptothecin Analogue, Generates New Topoisomerase I-Mediated DNA Breaks
1999
Marine natural products
2015 Standout
The Latest Research and Development into the Antibody–Drug Conjugate, [fam-] Trastuzumab Deruxtecan (DS-8201a), for HER2 Cancer Therapy
2019
Recent synthetic developments in a powerful imino Diels–Alder reaction (Povarov reaction): application to the synthesis of N-polyheterocycles and related alkaloids
2008 Standout
Towards new anticancer drugs: a decade of advances in synthesis of camptothecins and related alkaloids
2003
Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2
2005
Phase I study of topoisomerase I inhibitor exatecan mesylate (DX-8951f) given as weekly 24-hour infusions three of every four weeks.
2001
Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues
1998
7-Silylcamptothecins (silatecans): A new family of camptothecin antitumor agents
1997
THE LIPOXYGENASE PATHWAY
2002 Standout
Total Synthesis of Camptothecin and Related Natural Products by a Flexible Strategy
2016
Asymmetric Total Synthesis of Solandelactone E: Stereocontrolled Synthesis of the 2‐ene‐1,4‐diol Core through a Lithiation–Borylation–Allylation Sequence
2010
The Photochemical Synthesis of Fine Chemicals with Sunlight
1994
Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates
2015
Regioselective acylation of 1-hydroxypyrazoles via metalated intermediates
2002
Topoisomerase I-Mediated Antiproliferative Activity of Enantiomerically Pure Fluorinated Homocamptothecins
2000
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Hydrogen Autotransfer in the N-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles
2009 Standout
Multicomponent reactions: advanced tools for sustainable organic synthesis
2014 Standout
Purification and characterization of branched chain α-keto acid dehydrogenase complex of bovine kidney
1978
Die photochemische Synthese von Feinchemikalien mit Sonnenlicht
1994
Cytotoxic Oxylipins from a Marine Sponge Topsentia sp.
2006
Photosensitized singlet oxygen and its applications
2002 Standout
Avermectin Biosynthesis
1997 StandoutNobel
Total Synthesis of Camptothecin and Related Natural Products by a Flexible Strategy
2016
Cytotoxic Activities and Structure-Cytotoxic Relationships of Steroidal Saponins.
2001
Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
1999
Regioselective Functionalization of the Imidazole Ring via Transition Metal‐Catalyzed CN and CC Bond Forming Reactions
2010
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
A Practical Six-Step Synthesis of (S)-Camptothecin
2001
Recent Advances in the Friedländer Reaction
2009
Flavour formation by lactic acid bacteria and biochemical flavour profiling of cheese products
2005
Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application
2018 Standout
The Traditional Medicine and Modern Medicine from Natural Products
2016 Standout
Total synthesis of (+)-camptothecin
2002
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Randomized Phase III Study of Exatecan and Gemcitabine Compared With Gemcitabine Alone in Untreated Advanced Pancreatic Cancer
2006
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model.
2003
The Ehrlich Pathway for Fusel Alcohol Production: a Century of Research on Saccharomyces cerevisiae Metabolism
2008 Standout
Determination of the absolute configuration of marine oxylipin topsentolide A1 by the synthesis of the enantiomer of the natural product
2010
DNA Topoisomerases: Structure, Function, and Mechanism
2001 Standout
Works of Akio Ejima being referenced
Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives.
1999
Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist
2004
Antitumor Agents. VII. Synthesis and Antitumor Activity of Novel Hexacyclic Camptothecin Analogs
1994
Antitumor Agents. V. Synthesis and Antileukemic Activity of E-Ring-Modified (RS)-Camptothecin Analogues.
1992
Isolation and Characterization of Cytotoxic Compounds from Corn
1993
Cytotoxic Activities of Solanum Steroidal Glycosides.
1996
A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors in vitro and in vivo
1995
Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6
2000
Antiproliferative activity and mechanism of action of DZ-3358, a novel pyrimidinyl pyrazole derivative.
2000
Antitumour agents. Part 2. Asymmetric synthesis of (S)-camptothecin
1990
Synthesis and antileukemic activity of (.+-.)-20-deoxyaminocamptothecin analogues.
1989
Antitumor agents. III. A novel procedure for inversion of the configuration of a tertiary alcohol related to camptothecin.
1989
Synthesis and Antitumor Activity of Ring A- and F-Modified Hexacyclic Camptothecin Analogues
1998
Solid-Phase Synthesis of 2-(4-Carbamoylpyrazolyl)-4-alkylamino-6-aminopyrimidine Derivatives
2002
Synthesis and antimicrobial activity of cephalosporins with a 1-pyridinium substituent carrying a 5-membered heterocycle at the C-3 position.
1987
Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. II. Optimization of the Phenylpiperazine Moiety of 1-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes.
2002
Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. III. Synthesis and Antitumor Activity of 3-Phenylpiperazinyl-1-trans-propenes
2005
Asymmetric synthesis of (S)-camptothecin
1989
Antitumor Agents. VI. Synthesis and Antitumor Activity of Ring A-, Ring B-, and Ring C-Modified Derivatives of Camptothecin
1994
Coenzyme A- and Nicotinamide Adenine Dinucleotide-dependent Branched Chain α-Keto Acid Dehydrogenase
1969