Standout Papers
- Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509 (2008)
- A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium (2010)
- ChemInform Abstract: Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01‐0509. Part 1. Taxonomy, Fermentation, Isolation and Biological Properties. (2008)
- Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509 (2008)
Citation Impact
Citing Papers
Prolonged Impact of Antibiotics on Intestinal Microbial Ecology and Susceptibility to Enteric Salmonella Infection
2009
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
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The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
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Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
2010 StandoutScience
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
2004
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Sequence conservation in theSaccharomycesandKluveromycesGAL11 transcription acvivators suggests functional domains
1991
Total Synthesis and Determination of the Absolute Configuration of Guadinomines B and C2
2008 StandoutNobel
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
2009
Complete Genome Sequences of Rat and Mouse Segmented Filamentous Bacteria, a Potent Inducer of Th17 Cell Differentiation
2011
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Nomenclature for Factors of the HLA system, 1990
1991
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Common West African HLA antigens are associated with protection from severe malaria
1991 StandoutNature
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretion
2005
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Microbiotal influence on T cell subset development
2011
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
2005
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
Structural characterization of the molecular platform for type III secretion system assembly
2005 Nature
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
The type III secretion injectisome
2006
New structural insights into the bacterial type III secretion system
2006
Salmonella typhi uses CFTR to enter intestinal epithelial cells
1998 StandoutNatureNobel
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Intestinal Commensal Microbes as Immune Modulators
2012
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
2007
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
The bacterial injection kit: Type III secretion systems
2005
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
1994 StandoutNobel
Histone acetylation in chromatin structure and transcription
1997 StandoutNature
Protein delivery into eukaryotic cells by type III secretion machines
2006 Nature
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
2013 StandoutNature
Regulation of transcription and cell identity by POU domain proteins
1991 StandoutNobel
Genetic evidence for the interaction of the yeast transcriptional co-activator proteins GCN5 and ADA2
1995
Implication of Virulence Factors inEscherichia coliO157:H7 Pathogenesis
2003
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system
2009 StandoutNobel
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
The Saccharomyces cerevisiae SPT14 gene is essential for normal expression of the yeast transposon, Ty, as well as for expression of the HIS4 gene and several genes in the mating pathway
1991
Innate immune recognition of infected apoptotic cells directs TH17 cell differentiation
2009 Nature
The Shigella OspC3 Effector Inhibits Caspase-4, Antagonizes Inflammatory Cell Death, and Promotes Epithelial Infection
2013
Structural organization of yeast and mammalian mediator complexes
2000 StandoutNobel
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
Gut Microbiota in Health and Disease
2010 Standout
Enteropathogenic and EnterohemorrhagicEscherichia coliInfections: Translocation, Translocation, Translocation
2005
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest.
1992
The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function.
1996 StandoutNobel
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Structure and Total Synthesis of Fungal Calpinactam, A New Antimycobacterial Agent
2009 StandoutNobel
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
2004 StandoutNobel
Central Role for B Lymphocytes and CD4 + T Cells in Immunity to Infection by the Attaching and Effacing Pathogen Citrobacter rodentium
2003
Microbial metabolites: 45 years of wandering, wondering and discovering
2011 StandoutNobel
Synthesis and biological properties of tensyuic acids B, C, and E, and investigation of the optical purity of natural tensyuic acid B
2008 StandoutNobel
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.
1995 StandoutNobel
Evidence for a mediator cycle at the initiation of transcription
1997 StandoutNobel
Yeast Gal11 protein mediates the transcriptional activation signal of two different transacting factors, Gal4 and general regulatory factor I/repressor/activator site binding protein 1/translation upstream factor.
1990
Process of Protein Transport by the Type III Secretion System
2004
Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: exploiting the host cell cytoskeleton from the outside
2000
Conserved Structures of Mediator and RNA Polymerase II Holoenzyme
1999 StandoutScienceNobel
Yeast GAL11 protein is a distinctive type transcription factor that enhances basal transcription in vitro.
1993
Perturbation of the Small Intestine Microbial Ecology by Streptomycin Alters Pathology in a Salmonella enterica Serovar Typhimurium Murine Model of Infection
2009
Evidence that the Elongation Factor TFIIS Plays a Role in Transcription Initiation at GAL1 in Saccharomyces cerevisiae
2005
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Involvement of the SIN4 Global Transcriptional Regulator in the Chromatin Structure of Saccharomyces cerevisiae
1992
Azithromycin Inhibits the Formation of Flagellar Filaments without Suppressing Flagellin Synthesis in Salmonella enterica Serovar Typhimurium
2005 StandoutNobel
Mediator protein mutations that selectively abolish activated transcription
1999 StandoutNobel
The StcE Protease Contributes to Intimate Adherence of EnterohemorrhagicEscherichia coliO157:H7 to Host Cells
2005
Transmission Electron Microscopic Demonstration of Phagocytosis and Intracellular Processing of Segmented Filamentous Bacteria by Intestinal Epithelial Cells of the Chick Ileum
2000
Structure and Electrophysiological Properties of the YscC Secretin from the Type III Secretion System of Yersinia enterocolitica
2004
Segmented Filamentous Bacteria Interact with Intraepithelial Mononuclear Cells
2002
The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.
1990
Critical Role of T Cell-Dependent Serum Antibody, but Not the Gut-Associated Lymphoid Tissue, for Surviving Acute Mucosal Infection with Citrobacter rodentium, an Attaching and Effacing Pathogen
2004
Association of the Mediator complex with enhancers of active genes
2003 StandoutNobel
SALMONELLOSIS: Host Immune Responses and Bacterial Virulence Determinants1
1996
Works of Akio Abe being referenced
Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure
2001
Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion
1999
Targeting of Enteropathogenic Escherichia coli EspF to Host Mitochondria Is Essential for Bacterial Pathogenesis
2004
Segmented Filamentous Bacteria Prevent Colonization of EnteropathogenicEscherichia coliO103 in Rabbits
2000
Two distinct subtypes of theHLA-DRw12 haplotypes in the Japanese population detected by nucleotide sequence analysis and oligonucleotide genotyping
1989
Molecular mechanism of the regulation of expression of plasmid-encoded mouse bacteremia (mba) genes in Salmonella serovar Choleraesuis
1993
Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509
2008 StandoutNobel
In vivo interactions of rabbit enteropathogenic O103 with its host: an electron microscopic and histopathologic study
2000
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF‐H1
2004
Positive regulator for the expression of Mba protein of the virulence plasmid, pKDSC50, of Salmonella choleraesuis
1991
Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509
2008 StandoutNobel
Sequence analysis and oligonucleotide genotyping of HLA-DR“JX6”, a DR“blank” haplotype found in the Japanese population
1990
A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium
2010 StandoutNobel
Enterohemorrhagic Escherichia coli O157:H7 Produces Tir, Which Is Translocated to the Host Cell Membrane but Is Not Tyrosine Phosphorylated
1999
Two Enteropathogenic Escherichia coli Type III Secreted Proteins, EspA and EspB, Are Virulence Factors
1998
Assembly of the Type III Secretion Apparatus of Enteropathogenic Escherichia coli
2006
Role of EspB in Experimental Human Enteropathogenic Escherichia coli Infection
2000
GAL11 Protein, an Auxiliary Transcription Activator for Genes Encoding Galactose-Metabolizing Enzymes in Saccharomyces cerevisiae
1988