Citation Impact
Citing Papers
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Combinatorial computational method gives new picomolar ligands for a known enzyme
2002
IDconverter and IDClight: Conversion and annotation of gene and protein IDs
2007
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
Navigating chemical space for biology and medicine
2004 Nature
Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen
1997 Standout
Dynamic personalities of proteins
2007 StandoutNature
The evolving role of natural products in drug discovery
2005 Standout
Fragment-based lead discovery
2004
Further development and validation of empirical scoring functions for structure-based binding affinity prediction
2002
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
2005 StandoutNature
Rethinking amide bond synthesis
2011 StandoutNature
NMR-based screening technologies
2003
Structure-based screening of low-affinity compounds
2002
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Discovering novel ligands for macromolecules using X-ray crystallographic screening
2000
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Pharmacological inhibitors of MAPK pathways
2002
High-throughput crystallography for lead discovery in drug design
2002
The consequences of translational and rotational entropy lost by small molecules on binding to proteins
2002
Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
2004 StandoutNobel
Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists
2005 StandoutNobel
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
2008 Standout
Global Proteome Analysis of the NCI-60 Cell Line Panel
2013
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Deciphering common failures in molecular docking of ligand-protein complexes
2000
Drug research: myths, hype and reality
2003
Empirical potentials and functions for protein folding and binding
1997
Structure-based virtual screening: an overview
2002
Significance, detection and markers of disseminated breast cancer cells
2006
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
UCSF Chimera—A visualization system for exploratory research and analysis
2004 Standout
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
2008 Standout
Breast cancer genomes — form and function
2010
Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes
1997
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
2012 Standout
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Antagonists of protein–protein interactions
2000
Drug-like properties and the causes of poor solubility and poor permeability
2000 Standout
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
A review of protein-small molecule docking methods
2002
Chemistry challenges in lead optimization: silicon isosteres in drug discovery
2003
GoMiner: a resource for biological interpretation of genomic and proteomic data
2003
Features and development of Coot
2010 Standout
DOCK 4.0: Search strategies for automated molecular docking of flexible molecule databases
2001
Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water*
2000
Protein–ligand docking: Current status and future challenges
2006
A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase
2018 StandoutNobel
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
2006 Standout
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
2009 Standout
Molecular docking to ensembles of protein structures 1 1Edited by B. Honig
1997
The statistical-thermodynamic basis for computation of binding affinities: a critical review
1997
A miRNA Signature of Prion Induced Neurodegeneration
2008
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
2009 Standout
Improved protein–ligand docking using GOLD
2003 Standout
Fragment-based lead discovery: leads by design
2005
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Nmr in drug discovery
2002 StandoutNobel
Docking: Successes and Challenges
2005
Rings in Drugs
2014 Standout
Close agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculations
2004 StandoutNobel
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
What Do Medicinal Chemists Actually Make? A 50-Year Retrospective
2011
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
In Situ Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications
2004 StandoutNobel
Is There a Difference between Leads and Drugs? A Historical Perspective
2001
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Babel's tower revisited: a universal resource for cross-referencing across annotation databases
2006
Integrating Fragment Assembly and Biophysical Methods in the Chemical Advancement of Small-Molecule Antagonists of IL-2: An Approach for Inhibiting Protein−Protein Interactions
2004
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Development of a Knowledge-Based Potential for Crystals of Small Organic Molecules: Calculation of Energy Surfaces for C=0···H−N Hydrogen Bonds
2000
DAVID gene ID conversion tool
2008
New Approach to Molecular Docking and Its Application to Virtual Screening of Chemical Databases
2000
Molecular Dynamics: Survey of Methods for Simulating the Activity of Proteins
2006
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Automated flexible ligand docking method and its application for database search
1997
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
Consensus Scoring: A Method for Obtaining Improved Hit Rates from Docking Databases of Three-Dimensional Structures into Proteins
1999
Property Distributions: Differences between Drugs, Natural Products, and Molecules from Combinatorial Chemistry
2002
The maximal affinity of ligands
1999
Flexible docking using tabu search and an empirical estimate of binding affinity
1998
Distinguishing between Natural Products and Synthetic Molecules by Descriptor Shannon Entropy Analysis and Binary QSAR Calculations
2000
Cancer Genome Landscapes
2013 StandoutScience
Diverse Viewpoints on Computational Aspects of Molecular Diversity
2001
Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays
2003
Charting biologically relevant chemical space: A structural classification of natural products (SCONP)
2005
High-Throughput Screening in Drug Metabolism and Pharmacokinetic Support of Drug Discovery
2000
Second-Site NMR Screening with a Spin-Labeled First Ligand
2000
Scaffold Architecture and Pharmacophoric Properties of Natural Products and Trade Drugs: Application in the Design of Natural Product-Based Combinatorial Libraries
2001
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Clustering of low-energy conformations near the native structures of small proteins
1998 StandoutNobel
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Ajay being referenced
MatchMiner: a tool for batch navigation among gene and gene product identifiers
2003
The SHAPES strategy: an NMR-based approach for lead generation in drug discovery
1999
Designing Libraries with CNS Activity
1999
Can We Learn To Distinguish between “Drug-like” and “Nondrug-like” Molecules?
1998
Flexible ligand docking without parameter adjustment across four ligand–receptor complexes
1995
Computational Methods to Predict Binding Free Energy in Ligand-Receptor Complexes
1995
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel
2006
Kinase Patent Space Visualization Using Chemical Replacements
2006