Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Survivors of out-of-hospital cardiac arrest with apparently normal heart: Need for definition and standardized clinical evaluation
1997
MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia
1999 Standout
Ion channels: Function unravelled by dysfunction
2004
Molecular mechanism for an inherited cardiac arrhythmia
1995 Nature
hERG potassium channels and cardiac arrhythmia
2006 Nature
Optical Imaging of Calcium Transients in Neurons and Pharyngeal Muscle of C. elegans
2000 StandoutNobel
First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
2014 Standout
Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus
1998 StandoutNobel
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
1995 Standout
Drug-Induced Hepatotoxicity
2003 Standout
β2‐Adrenergic receptor overexpression in the developing mouse heart: evidence for targeted modulation of ion channels
1999 StandoutNobel
Cardiac-Resynchronization Therapy for the Prevention of Heart-Failure Events
2009 Standout
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels
2008 StandoutNobel
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
2008 Standout
A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism
2009
Circadian Pacemakers Blowing Hot and Cold—But They're Clocks, Not Thermometers
1997 StandoutNobel
Inflammation, stress, and diabetes
2005 Standout
An SCN9A channelopathy causes congenital inability to experience pain
2006 StandoutNature
Interaction between the sodium channel inactivation linker and domain III S4-S5
1997
Mutations in the alpha 1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegans
1997
Clinical Management of Patients with the Long QT Syndrome: Drugs, Devices, and Gene‐Specific Therapy
1997
The long QT syndrome
1997
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
1996
A myocardial lineage derives from Tbx18 epicardial cells
2008 StandoutNature
Are patients with asthma at increased risk of coronary heart disease?
2004
The QT Interval and Torsade de Pointes
1999
Myocarditis
2011 Standout
From Ionic Currents to Molecular Mechanisms
2000 Standout
IsK and KvLQT1: Mutation in Either of the Two Subunits of the Slow Component of the Delayed Rectifier Potassium Channel Can Cause Jervell and Lange-Nielsen Syndrome
1997
Interaction between Fast and Ultra-slow Inactivation in the Voltage-gated Sodium Channel
2002
Genomic Structure of Three Long QT Syndrome Genes:KVLQT1, HERG,andKCNE1
1998
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs
1993
Neural Science: A Century of Progress and the Mysteries that Remain
2000 StandoutNobel
A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel
1995 Standout
Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A
2011 StandoutNobel
β-adrenergic action on wild-type and KPQ mutant human cardiac Na+ channels: shift in gating but no change in Ca2+: Na+ selectivity
1999
A constitutively open potassium channel formed by KCNQ1 and KCNE3
2000 StandoutNature
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: Executive Summary
2008
Hypertrophic Cardiomyopathy
2002 Standout
Structure and function of voltage‐gated sodium channels
1998
Genetics in rhythm
1997
Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
2008 Standout
Pathophysiological Mechanisms of Dominant and Recessive KvLQT1 K+ Channel Mutations Found in Inherited Cardiac Arrhythmias
1997
Novel KCNQ1 and HERG missense mutations in Dutch long-QT families
1999
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
1998 Nature
Specific Role of the Truncated βIV-Spectrin Σ6 in Sodium Channel Clustering at Axon Initial Segments and Nodes of Ranvier
2006 StandoutNobel
Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families
2008
Acquired QT interval prolongation and HERG: implications for drug discovery and development
2004
A decade of discoveries in cardiac biology
2004
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Channelopathies: ion channel disorders of muscle as a paradigm for paroxysmal disorders of the nervous system
1997
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
2009 StandoutNobel
Myocarditis
2009 Standout
Cardiac excitation–contraction coupling
2002 StandoutNature
Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.
1996
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a
2002
Fluorine in medicinal chemistry
2007 Standout
KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias
1997
Gain of Function Mutants: Ion Channels and G Protein-Coupled Receptors
2000
Mutation of the Gene for I sK Associated With Both Jervell and Lange-Nielsen and Romano-Ward Forms of Long-QT Syndrome
1998
Essential Ca 2+ -Binding Motif for Ca 2+ -Sensitive Inactivation of L-Type Ca 2+ Channels
1995 Science
ADrosophilaCalcium Channel α1 Subunit Gene Maps to a Genetic Locus Associated with Behavioral and Visual Defects
1996 StandoutNobel
Cardiac Sodium Channel Gene Variants and Sudden Cardiac Death in Women
2007
Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels
2013
Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents
2001
2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy
2011 Standout
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
2006
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
PKD2 , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
1996 StandoutScience
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease)
2000 Standout
Randomization-based methods for correcting for treatment changes: examples from the Concorde trial
1999
Neural Science
2000 StandoutNobel
Sudden Cardiac Death
1998 Standout
Spectrum of Mutations in Long-QT Syndrome Genes
2000
Artificial Molecular Machines
2015 Standout
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
2008 Standout
Some aspects of cardiac heterogeneity
1994
Sodium Channel Inactivation Is Altered by Substitution of Voltage Sensor Positive Charges
1997
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment
2007 StandoutNobel
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
A novel connexin46 (GJA3) mutation in autosomal dominant congenital nuclear pulverulent cataract.
2004
Sodium channel Na v 1.6 is localized at nodes of Ranvier, dendrites, and synapses
2000
Molecular Analysis of the Putative Inactivation Particle in the Inactivation Gate of Brain Type IIA Na+ Channels
1997
Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases: hypertrophic cardiomyopathy, long-QT syndrome, and marfan syndrome : A statement for healthcare professionals from the councils on clinical cardiology, cardiovascular disease in the young, and basic science, american heart association
1998
Developmental Changes in Ionic Channel Activity in the Embryonic Murine Heart
1996
Part 14: Pediatric Advanced Life Support
2010 Standout
2012 ACCF/AHA/HRS Focused Update Incorporated Into the ACCF/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
2012
Hypoxia in the thymus: role of oxygen tension in thymocyte survival
2002
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis
2006 StandoutNobel
Cellular Basis for the ECG Features of the LQT1 Form of the Long-QT Syndrome
1998
Molecular Analysis of Potential Hinge Residues in the Inactivation Gate of Brain Type IIA Na+ Channels
1997
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of A.J. Moss being referenced
Effects of lipids and lipid‐lowering therapy on hemostatic factors in patients with myocardial infarction
2004
Asthma and the risk of cardiac events in the long QT syndrome
1999
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
1995 Standout
Clinical features of the idiopathic long QT syndrome.
1992
Use of Compliance Measures in an Analysis of the Effect of Diltiazem on Mortality and Reinfarction After Myocardial Infarction
1993
Intramyocardial Oxygen Tension
1968