Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
RNA tertiary interactions in the large ribosomal subunit: The A-minor motif
2001 StandoutNobel
Consistent blind protein structure generation from NMR chemical shift data
2008 StandoutNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Infectious enveloped RNA virus antigenic chimeras.
1992 StandoutNobel
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Ribosome-inactivating proteins from plants
1993
Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors against A. fumigatus, Human, and Bacterial Chitinases
2005
A Fast Flexible Docking Method using an Incremental Construction Algorithm
1996 Standout
Crystal structures of hevamine, a plant defence protein with chitinase and lysozyme activity, and its complex with an inhibitor
1994
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Exploring steric constraints on protein mutations using MAGE/PROBE
2000
Low-barrier hydrogen bonds and low fractionation factor bases in enzymic reactions
1992
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
2000 StandoutNobel
Predicting Deleterious Amino Acid Substitutions
2001 Standout
Structure and function of SNARE and SNARE-interacting proteins
2005
SURFNET: A program for visualizing molecular surfaces, cavities, and intermolecular interactions
1995
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin
1996
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
The 1.8 Å Resolution Structure of Hevamine, a Plant Chitinase/Lysozyme, and Analysis of the Conserved Sequence and Structure Motifs of Glycosyl Hydrolase Family 18
1996
Towards predicting Ca2+‐binding sites with different coordination numbers in proteins with atomic resolution
2008
An equivalent metal ion in one- and two-metal-ion catalysis
2008
UCSF Chimera—A visualization system for exploratory research and analysis
2004 Standout
Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit
1999 StandoutNatureNobel
Searching protein structure databases has come of age
1994
A fast and efficient method to generate biologically relevant conformations
1994
Mutation of active site residues of the puromycin-sensitive aminopeptidase: conversion of the enzyme into a catalytically inactive binding protein
2003
Structure of ricin B‐chain at 2.5 Å resolution
1991
π-π interactions: the geometry and energetics of phenylalanine-phenylalanine interactions in proteins
1991
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Structure of Human Chitotriosidase
2002
Psammaplin A, a chitinase inhibitor isolated from the fijian marine sponge Aplysinella rhax
2002
Structures and mechanisms of glycosyl hydrolases
1995 Standout
DOCK 4.0: Search strategies for automated molecular docking of flexible molecule databases
2001
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Analysis of zinc binding sites in protein crystal structures
1998
The Sarcin/Ricin Loop, a Modular RNA
1995
Nucleases: diversity of structure, function and mechanism
2010
Knowledge‐based protein secondary structure assignment
1995 Standout
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Protein clefts in molecular recognition and function.
1996
The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay.
1995 StandoutNobel
A general two-metal-ion mechanism for catalytic RNA.
1993 StandoutNobel
Structural basis of the action of thermolysin and related zinc peptidases
1988
Synthesis ofN-Acetylglucosaminyl and Diacetylchitobiosyl Amides of Heterocyclic Carboxylic Acids as Potential Chitinase Inhibitors
1999
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases
2003 Standout
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
How many catalytic RNAs? Ions and the Cheshire cat conjecture.
1993
The conformation of the sarcin/ricin loop from 28S ribosomal RNA.
1993
Simulations of RNA base pairs in a nanodroplet reveal solvation-dependent stability
2007 StandoutNobel
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
2020 StandoutNobel
Site-directed mutagenesis shows that tyrosine 248 of carboxypeptidase A does not play a crucial role in catalysis
1985 Nature
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
A structural view of evolutionary divergence
1999 StandoutNobel
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
Docking flexible molecules: A case study of three proteins
1995
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Catalytic Antibodies
1986 Science
Crystal structure of the ribosomal RNA domain essential for binding elongation factors
1998 StandoutNobel
Computer simulations of enzyme catalysis: Finding out what has been optimized by evolution
1998 StandoutNobel
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
Towards an integrated model of bacterial conjugation
2014
Ricin: structure, mode of action, and some current applications
1994
On Low-Barrier Hydrogen Bonds and Enzyme Catalysis
1995 StandoutScienceNobel
Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
1993
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: Mimicry of carbohydrate substrate
2002 StandoutNobel
Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system
1998 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Energy considerations show that low-barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds
1996 StandoutNobel
A Detailed View of a Ribosomal Active Site
1999 StandoutNobel
Structural insights into the catalytic mechanism of a family 18 exo-chitinase
2001
Redesigning Nature's Poisons to Create Anti-Tumor Reagents
1987 Science
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Low-Barrier Hydrogen Bonds and Enzymic Catalysis
1994 StandoutScience
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of A.F. Monzingo being referenced
The Structure of an Allosamidin Complex with the Coccidioides immitis Chitinase Defines a Role for a Second Acid Residue in Substrate-assisted Mechanism
2002
The structure and action of chitinases
1999
Structure of recombinant ricin A chain at 2.3 Å
1993
Chitinases, chitosanases, and lysozymes can be divided into procaryotic and eucaryotic families sharing a conserved core
1996
Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogs
1987
X-ray analysis of substrate analogs in the ricin A-chain active site
1992
The 2·5 Å Structure of Pokeweed Antiviral Protein
1993
Crystal Structure of an Endochitinase from Hordeum vulgare L. Seeds
1993
The Structure of the Minimal Relaxase Domain of MobA at 2.1 Å Resolution
2006
The X‐ray structure of a chitinase from the pathogenic fungus Coccidioides immitis
2000
Structure of a ricin mutant showing rescue of activity by a noncatalytic residue
1992
The three-dimensional structure of ricin at 2.8 A.
1987
Preliminary X-ray diffraction studies on an anti-viral protein
1977
Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin
1986
Structure of a mercaptan-thermolysin complex illustrates mode of inhibition of zinc proteases by substrate-analog mercaptans
1982
The refined crystal structure of an endochitinasefrom Hordeum vulgare L. seeds at 1.8 Å resolution
1995
Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography: a novel class of transition-state analogs for zinc peptidases
1984
An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides
1984