Citation Impact
Citing Papers
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
2006
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
2007 Standout
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
2007 Standout
Obesity alters gut microbial ecology
2005 Standout
Metagenomic Analysis of the Human Distal Gut Microbiome
2006 StandoutScience
Hormonal regulation of cholesterol 7alpha-hydroxylase specific activity, mRNA levels, and transcriptional activity in vivo in the rat
1997
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Structural alterations in lecithin-cholesterol vesicles following interactions with monomeric and micellar bile salts: physical-chemical basis for subselection of biliary lecithin species and aggregative states of biliary lipids during bile formation.
1990
A placebo-controlled study on the efficacy of aspirin and doxycycline in preventing clogging of biliary endoprostheses
1989
Kidney stones: pathophysiology and medical management
2006 Standout
Lipid flow in bile formation
1992
Formation of iso-ursodeoxycholic acid during administration of ursodeoxycholic acid in man
1991
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
1994 Standout
Changes of Intestinal Functions in Liver Cirrhosis
2016 Standout
Bowel Disorders
2016 Standout
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
REGULATION OF BILE ACID BIOSYNTHESIS
1999
Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease
2011
Bowel Functions, Fecal Unconjugated Primary and Secondary Bile Acids, and Colonic Transit in Patients With Irritable Bowel Syndrome
2013
Microbial tryptophan catabolites in health and disease
2018 Standout
The Negative Effects of Bile Acids and Tumor Necrosis Factor-α on the Transcription of Cholesterol 7α-Hydroxylase Gene (CYP7A1) Converge to Hepatic Nuclear Factor-4
2001
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
2006 StandoutNature
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
The role of the gut microbiota in nonalcoholic fatty liver disease
2010
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine
2007
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Enteric neurones modulate the colonic permeability response to luminal bile acids in rat colon in vivo
2004
Regulation of sterol 12α-hydroxylase and cholic acid biosynthesis in the rat
2000
Unlocking the potential of bile acids in synthesis, supramolecular/materials chemistry and nanoscience
2007
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
2017 Standout
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis
2000 Standout
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
2009
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Pathological bacterial translocation in liver cirrhosis
2013
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Down-regulation of the rat hepatic sterol 27-hydroxylase
1999
Insulin-like growth factor I improves intestinal barrier function in cirrhotic rats
2006
Obesity, Weight Gain, and the Risk of Kidney Stones
2005 Standout
Targeting multidrug resistance in cancer
2006 Standout
Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
2019 Standout
Effects of A3309, an Ileal Bile Acid Transporter Inhibitor, on Colonic Transit and Symptoms in Females With Functional Constipation
2011
Chenodeoxycholate in Females With Irritable Bowel Syndrome-Constipation: A Pharmacodynamic and Pharmacogenetic Analysis
2010
Coated Oral 5-Aminosalicylic Acid Therapy for Mildly to Moderately Active Ulcerative Colitis
1987 Standout
Structural Aspects of Bile Acids Involved in the Regulation of Cholesterol 7α‐Hydroxylase and Sterol 27‐Hydroxylase
1995
Gut-liver axis in liver cirrhosis: How to manage leaky gut and endotoxemia
2015
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver
1998
Human cecal bile acids: concentration and spectrum
2007
Randomised trial of self-expanding metal stents versus polyethylene stents for distal malignant biliary obstruction
1992 Standout
Dependence of Oxalate Absorption on the Daily Calcium Intake
2004
Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes Is Mediated by the c-Jun N-terminal Kinase Pathway
2001
A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation
2011
The Human Microbiome Project
2007 StandoutNature
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
2016 Standout
Stimulation of ATP secretion in the liver by therapeutic bile acids
2001
Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport
2006
Biliopancreatic diversion for obesity at eighteen years
1996
Bile Secretion and Liver Regeneration in Partially Hepatectomized Rats
1993
Tauro-β-muricholate preserves choleresis and prevents taurocholate-induced cholestasis in colchicine-treated rat liver
1992
Cystic Fibrosis Transmembrane Conductance Regulator Mediates the Cyclic Adenosine Monophosphate–Induced Fluid Secretion But Not the Inhibition of Resorption in Mouse Gallbladder Epithelium
1997 StandoutNobel
Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats
2015
Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.
1997
Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics
2008
Bile Acid Induction of Cytokine Expression by Macrophages Correlates with Repression of Hepatic Cholesterol 7α-Hydroxylase
2000
Interactions Between the Intestinal Microbiome and Liver Diseases
2014
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice
2012
Twenty-four–hour urine chemistries and the risk of kidney stones among women and men
2001
Bacterial translocation (BT) in cirrhosis†
2005
The human microbiome: at the interface of health and disease
2012 Standout
Regulation of bile acid synthesis
1998
Irritable Bowel Syndrome
2015 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Gut Microbiota in Health and Disease
2010 Standout
CPF: An orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7α-hydroxylase gene
1999
A Distinct Thyroid Hormone Response Element Mediates Repression of the Human Cholesterol 7α-Hydroxylase (CYP7A1) Gene Promoter
2002
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
2001 Standout
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
Microbial Translocation in Chronic Liver Diseases
2012
Vasoactive Intestinal Peptide and Secretin: Effects of Combined and Separate Intravenous Infusions on Bile Secretion in Man
1991
Theory and applications of ion-selective electrodes
1986
Bile Salt Transporters: Molecular Characterization, Function, and Regulation
2003
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
2008 Standout
Effects of calcium and pH on the mucosal damage produced by deoxycholic acid in the rat colon.
1986
First Chemical Synthesis, Aggregation Behavior and Cholesterol Solubilization Properties of Pythocholic Acid and 16α‐Hydroxycholic Acid
2007
Thyroid Hormone Regulation of Metabolism
2014 Standout
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
Liver Regeneration
1997 StandoutScience
How bile acids confer gut mucosal protection against bacteria
2006
Reverse-phase h.p.l.c. separation, quantification and preparation of bilirubin and its conjugates from native bile. Quantitative analysis of the intact tetrapyrroles based on h.p.l.c. of their ethyl anthranilate azo derivatives
1985
Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity
1987
Pathological bacterial translocation in cirrhosis: pathophysiology, diagnosis and clinical implications
2012
Clogging of biliary endoprostheses: a new perspective.
1990
The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxylase gene
2000
Lipopolysaccharide Endotoxins
2002 Standout
Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats.
1992
A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model
2007
Alcoholic Liver Disease: The Gut Microbiome and Liver Cross Talk
2015
A Novel Liver X Receptor Agonist Establishes Species Differences in the Regulation of Cholesterol 7α-Hydroxylase (CYP7a)
2002
Epimerization of the 7-hydroxy group of bile acids by the combination of two kinds of microorganisms with 7 alpha- and 7 beta-hydroxysteroid dehydrogenase activity, respectively.
1981
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Carrier-Based Ion-Selective Electrodes and Bulk Optodes. 2. Ionophores for Potentiometric and Optical Sensors
1998 Standout
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Alcohol and Gut-Derived Inflammation
2017
Gut Microbiota and Host Reaction in Liver Diseases
2015
27-Hydroxycholesterol: production rates in normal human subjects
1999
Works of A.F. Hofmann being referenced
Enzymatic measurement of choline-containing phospholipids in bile.
1981
Cholestatic liver disease: pathophysiology and therapeutic options
2002
Validation of [22,23-3H]cholic acid as a stable tracer through conversion to deoxycholic acid in human subjects
1996
Oral Bile Acids Reduce Bacterial Overgrowth, Bacterial Translocation, and Endotoxemia in Cirrhotic Rats
2003
Basal and bile salt-stimulated bile flow and biliary lipid excretion in ponies
1989
Pharmacologic effect of somatostatin on bile formation in the dog. Enhanced ductular reabsorption as the major mechanism of anticholeresis.
1983
Influence of bile acid structure on bile flow and biliary lipid secretion in the hamster
1984
A novel primary bile acid in the Shoebill stork and herons and its phylogenetic significance
2002
Hyperoxaluria associated with intestinal bypass surgery for morbid obesity: occurrence, pathogenesis and approaches to treatment.
1981
Effect of molecular structure on bile acid-induced alterations in absorptive function, permeability, and morphology in the perfused rabbit colon.
1979
Hypercholeresis induced by norchenodeoxycholate in biliary fistula rodent
1987
Bile acid secretion, bile flow and biliary lipid secretion in humans.
1990
Calcium oxalate-phosphate gallstones, a unique chemical type of gallstone.
1982
Pharmacologic Effect of Somatostatin on Bile Formation in the Dog
1983
Assay of urinary oxalate: six methodologies compared.
1983
Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids
1980
Transcriptional regulation of cholesterol 7 alpha-hydroxylase mRNA by conjugated bile acids in primary cultures of rat hepatocytes
1993
Simulation of the metabolism and enterohepatic circulation of endogenous chenodeoxycholic acid in man using a physiological pharmacokinetic model
1986
Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions
1991
Carrier-mediated transport of conjugated bile acids across the basolateral membrane of biliary epithelial cells
1997