Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Crystal Structure of a Human Alkylbase-DNA Repair Enzyme Complexed to DNA
1998
Structure of a Voltage-Dependent K+ Channel β Subunit
1999 StandoutNobel
Cation–π interactions in ligand recognition and catalysis
2002
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Evidence on close packing and cavities in proteins
1995
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation
1998
Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core
2012
Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control
2018
Stochastic Sensing of TNT with a Genetically Engineered Pore
2005
Crystallographic Refinement by Knowledge-Based Exploration of Complex Energy Landscapes
2005
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Testing homology modeling on mutant proteins: predicting structural and thermodynamic effects in the Ala98→Val mutants of T4 lysozyme
1996
Directed Evolution of ATP Binding Proteins from a Zinc Finger Domain by Using mRNA Display
2006 StandoutNobel
Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution
2001 StandoutNatureNobel
Crystal structure refinement withSHELXL
2014 Standout
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
1998
An mRNA m7G Cap Binding-like Motif within Human Ago2 Represses Translation
2007
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Transient water wires mediate selective proton transport in designed channel proteins
2023
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Designed Armadillo Repeat Proteins as General Peptide-Binding Scaffolds: Consensus Design and Computational Optimization of the Hydrophobic Core
2008
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
The Structural Basis of Hammerhead Ribozyme Self-Cleavage
1998
A short history ofSHELX
2007 Standout
An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate
1994
Viral and cellular mRNA capping: Past and prospects
2000
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Structure, mechanism, and evolution of the mRNA capping apparatus
2000
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
1993 StandoutNature
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Six Classes of Nuclear Localization Signals Specific to Different Binding Grooves of Importin α
2008
Super-resolution biomolecular crystallography with low-resolution data
2010 StandoutNatureNobel
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange
1996
Nucleocytoplasmic transport enters the atomic age
2001
Modeling side-chain conformation
1996
Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates
1998 StandoutNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Modular peptide binding: From a comparison of natural binders to designed armadillo repeat proteins
2013
Prediction of amino acid sequence from structure
2000
Designed Armadillo Repeat Proteins: Library Generation, Characterization and Selection of Peptide Binders with High Specificity
2012
Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
2006
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
Biophysical Studies of eIF4E Cap-binding Protein: Recognition of mRNA 5′ Cap Structure and Synthetic Fragments of eIF4G and 4E-BP1 Proteins
2002
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
Torsion angle dynamics: Reduced variable conformational sampling enhances crystallographic structure refinement
1994
Real-space refinement in PHENIX for cryo-EM and crystallography
2018 Standout
Substructure solution withSHELXD
2002 Standout
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Physical‐chemical determinants of turn conformations in globular proteins
2007
Coupling backbone flexibility and amino acid sequence selection in protein design
1997
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Core-packing constraints, hydrophobicity and protein design
1994
Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution
2000
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
How glutaminyl-tRNA synthetase selects glutamine
1998 StandoutNobel
Crystal structure of a paired domain-DNA complex at 2.5 å resolution reveals structural basis for pax developmental mutations
1995
Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1Aresolution
1998
De novo design of the hydrophobic cores of proteins
1995
PROTEIN FOLDING: The Endgame
1997 StandoutNobel
Structure at 2.7 Å resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody F V fragment
1997 Nobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
De NovoDesign of Helical Bundles as Models for Understanding Protein Folding and Function
2000
Repacking protein cores with backbone freedom: structure prediction for coiled coils.
1995
Phase Improvement by Multi-Start Simulated Annealing Refinement and Structure-Factor Averaging
1998
Quality Control by DNA Repair
1999 StandoutScienceNobel
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
1995
Crystal Structures of Three Misacylating Mutants of Escherichia coli Glutaminyl-tRNA Synthetase Complexed with tRNAGln and ATP
1996 StandoutNobel
Insights into Editing from an Ile-tRNA Synthetase Structure with tRNA Ile and Mupirocin
1999 StandoutScienceNobel
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors
2012 Science
COMPUTER-BASED DESIGN OF NOVEL PROTEIN STRUCTURES
2005
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
TAPping into mRNA Export
2001 StandoutScienceNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Structures of Normal Single-Stranded DNA and Deoxyribo-3‘-S-phosphorothiolates Bound to the 3‘-5‘ Exonucleolytic Active Site of DNA Polymerase I from Escherichia coli,
1998 StandoutNobel
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
Works of A.E. Hodel being referenced
Dissection of the Karyopherin α Nuclear Localization Signal (NLS)-binding Groove
2003
The 1.85 Å Structure of Vaccinia Protein VP39: A Bifunctional Enzyme That Participates in the Modification of Both mRNA Ends
1996
Evidence That the RNA Methylation and Poly(A) Polymerase Stimulatory Activities of Vaccinia Virus Protein VP39 Do Not Impinge upon One Another
1998
The importance of anchorage in determining a strained protein loop conformation
1994
Regulation of Nuclear Import by Phosphorylation Adjacent to Nuclear Localization Signals
2004
The Three-Dimensional Structure of the Autoproteolytic, Nuclear Pore-Targeting Domain of the Human Nucleoporin Nup98
2002
Nuclear Localization Signal Receptor Affinity Correlates with in Vivo Localization in Saccharomyces cerevisiae
2006
Dissection of a Nuclear Localization Signal
2001
Structural Basis for Sequence-Nonspecific Recognition of 5′-Capped mRNA by a Cap-Modifying Enzyme
1998
Conformational substrates and uncertainty in macromolecular free energy calculations
1993
Model bias in macromolecular crystal structures
1992
Structural Requirements for the Specific Recognition of an m7G mRNA Cap
2000
Recognition of Capped RNA Substrates by VP39, the Vaccinia Virus-Encoded mRNA Cap-Specific 2‘-O-Methyltransferase
1998
mRNA cap recognition: Dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains
1999
The crystal structure of a mutant protein with altered but improved hydrophobic core packing.
1994