Citation Impact
Citing Papers
hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer
2008
Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
2009 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Adaptive Therapy
2009
Genetic evidence for a tumor suppressor role of HIF-2α
2005
Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
2015
Two transactivation mechanisms cooperate for the bulk of HIF‐1‐responsive gene expression
2005
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance
2008
Role of hypoxia-inducible factor in cell survival during myocardial ischemia–reperfusion
2008
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α
2007
Role of monocarboxylate transporters in human cancers: state of the art
2012
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Role of Carcinoma-Associated Fibroblasts and Hypoxia in Tumor Progression
2010
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Hypoxia-inducible factors in the kidney
2006
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
2006 Standout
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Fetal Growth Plate
2007
Cancer Metastasis: Building a Framework
2006 Standout
SWI/SNF Regulates the Cellular Response to Hypoxia
2008
Tumor hypoxia and cancer progression
2005
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Viral vectors: from virology to transgene expression
2008
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
2006 StandoutNobel
Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia
2006
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
2006
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia
2006
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Cooperativity of Stress-Responsive Transcription Factors in Core Hypoxia-Inducible Factor Binding Regions
2012
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Mitochondria in cancer cells: what is so special about them?
2008
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue
2008
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia
2008
Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia
2009
Clonal evolution in cancer
2012 StandoutNature
The Hallmarks of Aging
2013 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Harnessing the hypoxia-inducible factor in cancer and ischemic disease
2006
Roxadustat (FG-4592)
2015
FOXO3a Is Activated in Response to Hypoxic Stress and Inhibits HIF1-Induced Apoptosis via Regulation of CITED2
2007
Genome-wide expression analysis using microarray identified complex signaling pathways modulated by hypoxia in nasopharyngeal carcinoma
2007
Phosphatidylinositol 3-kinase pathway regulates hypoxia-inducible factor-1 to protect from intestinal injury during necrotizing enterocolitis
2007
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation
2007
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Life with Oxygen
2007 StandoutScienceNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Hif-1α regulates differentiation of limb bud mesenchyme and joint development
2007
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Enhanced Bone Regeneration Associated With Decreased Apoptosis in Mice With Partial HIF-1α Deficiency
2006 StandoutNobel
Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment
2018
HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
2010 StandoutNobel
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Stabilized HIF‐1α is superior to VEGF for angiogenesis in skeletal muscle via adeno‐associated virus gene transfer
2005
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Works of A.E. Greijer being referenced
Up‐regulation of gene expression by hypoxia is mediated predominantly by hypoxia‐inducible factor 1 (HIF‐1)
2005
Hypoxia‐Induced Acidification Causes Mitoxantrone Resistance Not Mediated by Drug Transporters in Human Breast Cancer Cells
2005
Optimized conditions for the production of recombinant amphotropic retroviral vector preparations
1997
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis: Figure 1
2004